Browsing by Author Schluep, T

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Showing results 10 to 22 of 22 < previous 
TitleAuthor(s)Issue DateViews
 
Long-term serological, virological and histological responses to RNA inhibition by ARC-520 in Chinese chronic hepatitis B patients on entecavir treatment
Journal:Gut
Yuen, MFWong, DKHSchluep, TLai, CLFerrari, CLocarnini, SLo, RCLGish, RHamilton, JWooddell, CIMak, LYGiven, BD
2021
16
 
Predicting HBsAg clearance responses during ARC-520 RNA interference (RNAi) therapy based on HBsAg epitope profile analysis
Proceeding/Conference:Journal of Hepatology
Walsh, RYuen, LHammond, RDeerain, JGiven, BSchluep, TYuen, MFChan, HLYLai, CLHamilton, JLau, JYFerrari, CGish, RGLocarnini, SA
2016
39
 
Prolonged RNA interference therapy with ARC-520 Injection in treatment naïve, HBeAg positive and negative patients with chronic HBV results in significant reductions of HBs antigen
Proceeding/Conference:Journal of Hepatology
Yuen, RMFLiu, SHKChan, HLYGiven, BDSchluep, THamilton, JLai, CLLocarnini, SALau, JYFerrari, CGish, RG
2017
 
RNA interference therapy with ARC-520 Injection results in long term off-therapy antigen reductions in treatment naïve, HBeAg positive and negative patients with chronic HBV
Proceeding/Conference:Journal of Hepatology
Yuen, RMFLiu, SHKGiven, BSchluep, THamilton, JLai, CLLocarnini, SJackson, KLai, JYFerrari, CGish, RG.
2018
 
RNA Interference Therapy With ARC‐520 Results in Prolonged Hepatitis B Surface Antigen Response in Patients With Chronic Hepatitis B Infection
Journal:Hepatology
Yuen, MFSchiefke, IYoon, JHAhn, SHHeo, JKim, JHChan, HLYYoon, KTKlinker, HManns, MPetersen, JSchluep, THamilton, JGiven, BDFerrari, CLai, CLLocarnini, SAGish, RG
2020
20
 
RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg
Journal:Science Translational Medicine
Wooddell, CIYuen, RMFChan, HLYGish, RGLocarnini, SAChavez, DFerrari, CGiven, BDHamilton, JKanner, SBLai, CLLai, JYNSchluep, TXu, ZLanford, RELewis, DL
2017
32
 
Safety, Tolerability, and Pharmacokinetics of ARC-520 Injection, an RNA Interference-Based Therapeutic for the Treatment of Chronic Hepatitis B Virus Infection, in Healthy Volunteers
Journal:Clinical Pharmacology in Drug Development
Schluep, TLickliter, JHamilton, JLewis, DLLai, CLLau, JYNLocarnini, SAGish, RGGiven, BD
2017
51
 
Short interfering RNA JNJ-3989 combination therapy in chronic hepatitis B shows potent reduction of all viral markers but no correlate was identified for HBsAg reduction and baseline factors
Proceeding/Conference:Journal of Hepatology
Gane, ELocarnini, SLim, THStrasser, SSievert, WCheng, WThompson, AGiven, BSchluep, THamilton, JBiermer, MKalmeijer, RBeumont-Mauviel, MLenz, ODe Ridder, FCloherty, GWong, DKHSchwabe, CJackson, KFerrari, CLai, CLGish, RGYuen, RMF
2021
1
 
Short interfering RNA JNJ-3989 combination therapy in chronic hepatitis B (CHB) shows potent reduction of all viral markers but no correlate was identified for HBsAg reduction and baseline factors
Proceeding/Conference:APASL 2022, Seoul, Korea, 30 Mar - 3 Apr 2022. Hepatology International
Gane, ELocarnini, SLim, THStrasser, SISievert, WCheng, WThompson, AJGiven, BDSchluep, THamilton, JBiermer, MKalmeijer, RBeumont, MLenz, ORidder, FDCloherty, GWong, DKHSchwabe, CJackson, KFerrari, CLai, CLGish, RYuen, RMF
2022
 
Short term RNA interference therapy in chronic hepatitis B using JNJ-3989 brings majority of patients to HBsAg < 100 IU/ml threshold
Proceeding/Conference:Journal of Hepatology
Yuen, RMFLocarnini, SLim, THStrasser, SSievert, WCheng, WThompson, AGiven, BSchluep, THamilton, JCloherty, GWong, DKHSchwabe, CJackson, KFerrari, CLai, CLGish, RGGane, E
2019
73
 
Short-term treatment with RNA interference therapy, JNJ-3989, results in sustained hepatitis B surface antigen suppression in patients with chronic hepatitis B receiving nucleos(t)ide analogue treatment
Proceeding/Conference:Journal of Hepatology
Gane, ELocarnini, SLim, THStrasser, SSievert, WCheng, WThompson, AGiven, BSchluep, THamilton, JBiermer, MKalmeijer, RBeumont-Mauviel, MLenz, OCloherty, GWong, DKHSchwabe, CJackson, KFerrari, CLai, CLGish, RGYuen, RMF
2020
3
 
Synthetic RNAi triggers and their use in chronic hepatitis B therapies with curative intent
Journal:Antiviral Research
Gish, RGYuen, RMFChan, HLYGiven, BDLai, CLLocarnini, SALau, JYNWooddell, CISchluep, TLewis, DL
2015
 
Utility of a new HBV RNA assay in HBeAg positive and negative CHB and following HBsAg seroclearance in patients treated with ARC‐520, an RNAi drug targeting cccDNA derived HBV mRNA
Proceeding/Conference:Journal of Viral Hepatitis
Buter, EKWong, DKHJackson, KSchluep, TGersch, JKuhns, MCloherty, GALocarnini, SYuen, RMF
2018
52
Showing results 10 to 22 of 22 < previous