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Article: Herba Epimedii: Anti-oxidative properties and its medical implications

TitleHerba Epimedii: Anti-oxidative properties and its medical implications
Authors
Wing Sze, SCTong, YNg, TBYin Cheng, CLCheung, HP
KeywordsAnti-oxidant
Flavonoids
Herba Epimedii
Icarrin
Polysaccharides
Vitamin C
Issue Date2010
PublisherMolecular Diversity Preservation International. The Journal's web site is located at http://www.mdpi.org/molecules
Citation
Molecules, 2010, v. 15 n. 11, p. 7861-7870 How to Cite?
DOI: http://dx.doi.org/10.3390/molecules15117861
AbstractHerba Epimedii is a Chinese herbal medicine with proven efficacy in treating cardiovascular diseases and osteoporosis, and in improving sexual and neurological functions. This efficacy is found to be related to the potent anti-oxidative ability of Herba Epimedii and its flavonoid components, with icarrin as the main effective constituent, along with polysaccharides and vitamin C. These ingredients have been proven to be effective against oxidative-stress related pathologies (cardiovascular diseases, Alzheimer's disease and inflammation) in animal rodent models and in vitro studies. Their antioxidative properties are found to be related to an inductive effect on endogenous freeradical scavenging enzymes such as catalase and glutathione peroxidase and the inherent electron-donating ability of flavonoids. © 2010 licensee MDPI, Basel, Switzerland.
Persistent Identifierhttp://hdl.handle.net/10722/141042
ISSN
1420-3049
2021 Impact Factor: 4.927
2020 SCImago Journal Rankings: 0.782
ISI Accession Number ID
WOS:000284582100022
Funding AgencyGrant Number
University of Hong Kong200907160017
200802160025
Funding Information:

This research was supported in part by a grant from Seed Funding Programme for Applied Research (no. 200907160017 and 200802160025), the University of Hong Kong.

References
References in Scopus
Grants
Bioactive Components of Erxian Decoction as a Potential Drug Candidate for Peri-menopausal Syndrome
An Innovative Approach for Research and Development of Novel Scientific Chinese Medicine Formula: Erxian Decoction for Relieving Menopause Syndrome as a Study Model

 

DC FieldValueLanguage
dc.contributor.authorWing Sze, SCen_HK
dc.contributor.authorTong, Yen_HK
dc.contributor.authorNg, TBen_HK
dc.contributor.authorYin Cheng, CLen_HK
dc.contributor.authorCheung, HPen_HK
dc.date.accessioned2011-09-23T06:24:14Z-
dc.date.available2011-09-23T06:24:14Z-
dc.date.issued2010en_HK
dc.identifier.citationMolecules, 2010, v. 15 n. 11, p. 7861-7870en_HK
dc.identifier.issn1420-3049en_HK
dc.identifier.urihttp://hdl.handle.net/10722/141042-
dc.description.abstractHerba Epimedii is a Chinese herbal medicine with proven efficacy in treating cardiovascular diseases and osteoporosis, and in improving sexual and neurological functions. This efficacy is found to be related to the potent anti-oxidative ability of Herba Epimedii and its flavonoid components, with icarrin as the main effective constituent, along with polysaccharides and vitamin C. These ingredients have been proven to be effective against oxidative-stress related pathologies (cardiovascular diseases, Alzheimer's disease and inflammation) in animal rodent models and in vitro studies. Their antioxidative properties are found to be related to an inductive effect on endogenous freeradical scavenging enzymes such as catalase and glutathione peroxidase and the inherent electron-donating ability of flavonoids. © 2010 licensee MDPI, Basel, Switzerland.en_HK
dc.languageengen_US
dc.publisherMolecular Diversity Preservation International. The Journal's web site is located at http://www.mdpi.org/moleculesen_HK
dc.relation.ispartofMoleculesen_HK
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectAnti-oxidanten_HK
dc.subjectFlavonoidsen_HK
dc.subjectHerba Epimediien_HK
dc.subjectIcarrinen_HK
dc.subjectPolysaccharidesen_HK
dc.subjectVitamin Cen_HK
dc.subject.meshAntioxidants - chemistry - pharmacology-
dc.subject.meshAscorbic Acid - chemistry - pharmacology-
dc.subject.meshCells - drug effects-
dc.subject.meshDrugs, Chinese Herbal - pharmacology-
dc.subject.meshEpimedium - chemistry-
dc.titleHerba Epimedii: Anti-oxidative properties and its medical implicationsen_HK
dc.typeArticleen_HK
dc.identifier.emailWing Sze, SC: stephens@hku.hken_HK
dc.identifier.emailTong, Y: tongyao@hku.hken_HK
dc.identifier.authorityWing Sze, SC=rp00514en_HK
dc.identifier.authorityTong, Y=rp00509en_HK
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3390/molecules15117861en_HK
dc.identifier.pmid21060294-
dc.identifier.scopuseid_2-s2.0-78649472934en_HK
dc.identifier.hkuros194476en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-78649472934&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume15en_HK
dc.identifier.issue11en_HK
dc.identifier.spage7861en_HK
dc.identifier.epage7870en_HK
dc.identifier.eissn1420-3049-
dc.identifier.isiWOS:000284582100022-
dc.publisher.placeSwitzerlanden_HK
dc.relation.projectBioactive Components of Erxian Decoction as a Potential Drug Candidate for Peri-menopausal Syndrome-
dc.relation.projectAn Innovative Approach for Research and Development of Novel Scientific Chinese Medicine Formula: Erxian Decoction for Relieving Menopause Syndrome as a Study Model-
dc.identifier.scopusauthoridWing Sze, SC=23482617000en_HK
dc.identifier.scopusauthoridTong, Y=9045384000en_HK
dc.identifier.scopusauthoridNg, TB=35311803300en_HK
dc.identifier.scopusauthoridYin Cheng, CL=36647102000en_HK
dc.identifier.scopusauthoridCheung, HP=37033470100en_HK
dc.identifier.issnl1420-3049-

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