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Article: Recent advances in bioinorganic chemistry of bismuth

TitleRecent advances in bioinorganic chemistry of bismuth
Authors
Li, HSun, H
Issue Date2012
PublisherElsevier Ltd, Current Opinion Journals. The Journal's web site is located at http://www.elsevier.com/locate/cbi
Citation
Current Opinion in Chemical Biology, 2012, v. 16 n. 1-2, p. 74-83 How to Cite?
DOI: http://dx.doi.org/10.1016/j.cbpa.2012.01.006
AbstractBismuth has been used in medicine for over two centuries for the treatment of various diseases, in particular for gastrointestinal disorders, owing to its antimicrobial activity. Recent structural characterization of bismuth drugs provides an insight into assembly and pharmacokinetic pathway of the drugs. Mining potential protein targets inside the pathogen via metallomic/metalloproteomic approach and further characterization on the interactions of bismuth drugs with these targets laid foundation in understanding the mechanism of action of bismuth drugs. Such studies would be beneficial in rational design of new potential drugs.
Persistent Identifierhttp://hdl.handle.net/10722/159376
ISSN
1367-5931
2021 Impact Factor: 8.972
2020 SCImago Journal Rankings: 3.064
ISI Accession Number ID
WOS:000303640400011
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorLi, Hen_HK
dc.contributor.authorSun, Hen_HK
dc.date.accessioned2012-08-16T05:48:56Z-
dc.date.available2012-08-16T05:48:56Z-
dc.date.issued2012en_HK
dc.identifier.citationCurrent Opinion in Chemical Biology, 2012, v. 16 n. 1-2, p. 74-83en_HK
dc.identifier.issn1367-5931en_HK
dc.identifier.urihttp://hdl.handle.net/10722/159376-
dc.description.abstractBismuth has been used in medicine for over two centuries for the treatment of various diseases, in particular for gastrointestinal disorders, owing to its antimicrobial activity. Recent structural characterization of bismuth drugs provides an insight into assembly and pharmacokinetic pathway of the drugs. Mining potential protein targets inside the pathogen via metallomic/metalloproteomic approach and further characterization on the interactions of bismuth drugs with these targets laid foundation in understanding the mechanism of action of bismuth drugs. Such studies would be beneficial in rational design of new potential drugs.en_HK
dc.languageengen_US
dc.publisherElsevier Ltd, Current Opinion Journals. The Journal's web site is located at http://www.elsevier.com/locate/cbien_HK
dc.relation.ispartofCurrent Opinion in Chemical Biologyen_HK
dc.rightsNOTICE: this is the author’s version of a work that was accepted for publication in Current Opinion in Chemical Biology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Current Opinion in Chemical Biology, 2012, v. 16 n. 1-2, p. 74-83. DOI: 10.1016/j.cbpa.2012.01.006-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subject.meshBismuth - chemistry - metabolismen_HK
dc.subject.meshDrug Designen_HK
dc.subject.meshHumansen_HK
dc.subject.meshOrganic Chemistry Phenomenaen_HK
dc.subject.meshProteins - chemistry - metabolismen_HK
dc.titleRecent advances in bioinorganic chemistry of bismuthen_HK
dc.typeArticleen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1367-5931&volume=16&spage=74&epage=83&date=2012&atitle=Recent+advances+in+bioinorganic+chemistry+of+bismuthen_US
dc.identifier.emailLi, H: hylichem@hku.hken_HK
dc.identifier.emailSun, H: hsun@hku.hk-
dc.identifier.authoritySun, H=rp00777en_HK
dc.description.naturepostprint-
dc.identifier.doi10.1016/j.cbpa.2012.01.006en_HK
dc.identifier.pmid22322154-
dc.identifier.scopuseid_2-s2.0-84862813658en_HK
dc.identifier.hkuros205075en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84862813658&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume16en_HK
dc.identifier.issue1-2en_HK
dc.identifier.spage74en_HK
dc.identifier.epage83en_HK
dc.identifier.isiWOS:000303640400011-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridSun, H=7404827446en_HK
dc.identifier.scopusauthoridLi, H=37063577200en_HK
dc.identifier.citeulike10365682-
dc.identifier.issnl1367-5931-

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