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Article: Abnormal erythropoiesis in erythroleukemia: A fluorescence in situ hybridization study

TitleAbnormal erythropoiesis in erythroleukemia: A fluorescence in situ hybridization study
Authors
Wong, KFChu, YCKwong, YL
Issue Date1998
PublisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergene
Citation
Cancer Genetics And Cytogenetics, 1998, v. 105 n. 2, p. 187-189 How to Cite?
DOI: http://dx.doi.org/10.1016/S0165-4608(98)00008-9
AbstractErythroleukemia is an uncommon leukemia with heterogeneous morphologic and karyotypic features. Some cases might actually represent acute myeloid leukemia with a reactive erythroid hyperplasia. In this report, we described a 68-year-old woman with erythroleukemia and monosomy 7 and showed by fluorescence in situ hybridization that both myeloid and erythroid lineage were clonally involved and that both normal and abnormal erythroid populations coexisted, albeit indistinguishable by morphological examination. These findings may account for the variation in the erythropoietic activity observed in the clinical course of erythroleukemia.
Persistent Identifierhttp://hdl.handle.net/10722/162254
ISSN
0165-4608
2012 Impact Factor: 1.929
ISI Accession Number ID
WOS:000075452600018
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorWong, KFen_US
dc.contributor.authorChu, YCen_US
dc.contributor.authorKwong, YLen_US
dc.date.accessioned2012-09-05T05:18:26Z-
dc.date.available2012-09-05T05:18:26Z-
dc.date.issued1998en_US
dc.identifier.citationCancer Genetics And Cytogenetics, 1998, v. 105 n. 2, p. 187-189en_US
dc.identifier.issn0165-4608en_US
dc.identifier.urihttp://hdl.handle.net/10722/162254-
dc.description.abstractErythroleukemia is an uncommon leukemia with heterogeneous morphologic and karyotypic features. Some cases might actually represent acute myeloid leukemia with a reactive erythroid hyperplasia. In this report, we described a 68-year-old woman with erythroleukemia and monosomy 7 and showed by fluorescence in situ hybridization that both myeloid and erythroid lineage were clonally involved and that both normal and abnormal erythroid populations coexisted, albeit indistinguishable by morphological examination. These findings may account for the variation in the erythropoietic activity observed in the clinical course of erythroleukemia.en_US
dc.languageengen_US
dc.publisherElsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/cancergeneen_US
dc.relation.ispartofCancer Genetics and Cytogeneticsen_US
dc.rightsCancer Genetics and Cytogenetics. Copyright © Elsevier Inc.-
dc.subject.meshAgeden_US
dc.subject.meshChromosomes, Human, Pair 7en_US
dc.subject.meshErythropoiesis - Geneticsen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshIn Situ Hybridization, Fluorescenceen_US
dc.subject.meshLeukemia, Erythroblastic, Acute - Blood - Geneticsen_US
dc.subject.meshMonosomyen_US
dc.titleAbnormal erythropoiesis in erythroleukemia: A fluorescence in situ hybridization studyen_US
dc.typeArticleen_US
dc.identifier.emailKwong, YL:ylkwong@hku.hken_US
dc.identifier.authorityKwong, YL=rp00358en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0165-4608(98)00008-9en_US
dc.identifier.pmid9723040-
dc.identifier.scopuseid_2-s2.0-0032171478en_US
dc.identifier.hkuros41947-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032171478&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume105en_US
dc.identifier.issue2en_US
dc.identifier.spage187en_US
dc.identifier.epage189en_US
dc.identifier.isiWOS:000075452600018-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridWong, KF=7404759860en_US
dc.identifier.scopusauthoridChu, YC=55209144200en_US
dc.identifier.scopusauthoridKwong, YL=7102818954en_US
dc.identifier.issnl0165-4608-

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