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Article: Isolated lymph node T lymphoblastic transformation of chronic myeloid leukemia during interferon treatment

TitleIsolated lymph node T lymphoblastic transformation of chronic myeloid leukemia during interferon treatment
Authors
Au, WYChan, ACLKwong, YL
KeywordsChronic myeloid leukemia
T lymphoblastic lymphoma
Issue Date1999
PublisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35105
Citation
American Journal Of Hematology, 1999, v. 62 n. 4, p. 256-258 How to Cite?
DOI: http://dx.doi.org/10.1002/(SICI)1096-8652(199912)62:4<256::AID-AJH12>3.0.CO;2-B
AbstractIsolated nodal T lymphoblastic transformation of chronic myeloid leukemia (CML) with the marrow still in chronic phase is rare. A case of CML treated by α-interferon developed this unusual complication. However, after successful treatment of the blastic transformation, the patient remained responsive to interferon and maintained a major cytogenetic response for over 2 years. This case illustrated a rare clinical progression of CML on interferon treatment to isolated nodal T lymphoblastic transformation. This unusual form of blastic transformation may have a better prognosis than other forms of blastic crisis.
Persistent Identifierhttp://hdl.handle.net/10722/162287
ISSN
0361-8609
2021 Impact Factor: 13.265
2020 SCImago Journal Rankings: 2.456
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorAu, WYen_US
dc.contributor.authorChan, ACLen_US
dc.contributor.authorKwong, YLen_US
dc.date.accessioned2012-09-05T05:18:41Z-
dc.date.available2012-09-05T05:18:41Z-
dc.date.issued1999en_US
dc.identifier.citationAmerican Journal Of Hematology, 1999, v. 62 n. 4, p. 256-258en_US
dc.identifier.issn0361-8609en_US
dc.identifier.urihttp://hdl.handle.net/10722/162287-
dc.description.abstractIsolated nodal T lymphoblastic transformation of chronic myeloid leukemia (CML) with the marrow still in chronic phase is rare. A case of CML treated by α-interferon developed this unusual complication. However, after successful treatment of the blastic transformation, the patient remained responsive to interferon and maintained a major cytogenetic response for over 2 years. This case illustrated a rare clinical progression of CML on interferon treatment to isolated nodal T lymphoblastic transformation. This unusual form of blastic transformation may have a better prognosis than other forms of blastic crisis.en_US
dc.languageengen_US
dc.publisherJohn Wiley & Sons, Inc. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/35105en_US
dc.relation.ispartofAmerican Journal of Hematologyen_US
dc.rightsAmerican Journal of Hematology. Copyright © John Wiley & Sons, Inc.-
dc.subjectChronic myeloid leukemia-
dc.subjectT lymphoblastic lymphoma-
dc.subject.meshAntineoplastic Combined Chemotherapy Protocols - Therapeutic Useen_US
dc.subject.meshBone Marrow - Pathologyen_US
dc.subject.meshChromosomes, Human, Pair 22en_US
dc.subject.meshChromosomes, Human, Pair 9en_US
dc.subject.meshFusion Proteins, Bcr-Abl - Geneticsen_US
dc.subject.meshHumansen_US
dc.subject.meshImmunophenotypingen_US
dc.subject.meshIn Situ Hybridization, Fluorescenceen_US
dc.subject.meshInterferon-Alpha - Therapeutic Useen_US
dc.subject.meshLeukemia, Myelogenous, Chronic, Bcr-Abl Positive - Genetics - Pathology - Therapyen_US
dc.subject.meshLymph Nodes - Pathologyen_US
dc.subject.meshLymphocyte Activationen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshRemission Inductionen_US
dc.subject.meshT-Lymphocytes - Pathologyen_US
dc.subject.meshTranslocation, Geneticen_US
dc.titleIsolated lymph node T lymphoblastic transformation of chronic myeloid leukemia during interferon treatmenten_US
dc.typeArticleen_US
dc.identifier.emailKwong, YL:ylkwong@hku.hken_US
dc.identifier.authorityKwong, YL=rp00358en_US
dc.description.naturelink_to_OA_fulltexten_US
dc.identifier.doi10.1002/(SICI)1096-8652(199912)62:4<256::AID-AJH12>3.0.CO;2-Ben_US
dc.identifier.pmid10589085-
dc.identifier.scopuseid_2-s2.0-0032735921en_US
dc.identifier.hkuros49590-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0032735921&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume62en_US
dc.identifier.issue4en_US
dc.identifier.spage256en_US
dc.identifier.epage258en_US
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridAu, WY=7202383089en_US
dc.identifier.scopusauthoridChan, ACL=16047349300en_US
dc.identifier.scopusauthoridKwong, YL=7102818954en_US
dc.identifier.issnl0361-8609-

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