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Article: Chemoenzymatic synthesis of macrocyclic polyamines

TitleChemoenzymatic synthesis of macrocyclic polyamines
Authors
Lu, WSih, CJ
Issue Date1999
PublisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/tetlet
Citation
Tetrahedron Letters, 1999, v. 40 n. 27, p. 4965-4968 How to Cite?
DOI: http://dx.doi.org/10.1016/S0040-4039(99)00954-5
Abstract(±)-Azamacrolides were synthesized via lipase-catalyzed intramolecular cyclization of (±)-hydroxy-azaesters. Further, the size of the macrocyclic lactones formed could be altered by the substituent on the nitrogen atom. This allows one to prepare a combinatorial library of azamacrolides from a small number of hydroxy-azaesters using this biocatalytic approach.
Persistent Identifierhttp://hdl.handle.net/10722/167622
ISSN
0040-4039
2021 Impact Factor: 2.032
2020 SCImago Journal Rankings: 0.541
ISI Accession Number ID
WOS:000081122400012
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorLu, Wen_US
dc.contributor.authorSih, CJen_US
dc.date.accessioned2012-10-08T03:09:08Z-
dc.date.available2012-10-08T03:09:08Z-
dc.date.issued1999en_US
dc.identifier.citationTetrahedron Letters, 1999, v. 40 n. 27, p. 4965-4968en_US
dc.identifier.issn0040-4039en_US
dc.identifier.urihttp://hdl.handle.net/10722/167622-
dc.description.abstract(±)-Azamacrolides were synthesized via lipase-catalyzed intramolecular cyclization of (±)-hydroxy-azaesters. Further, the size of the macrocyclic lactones formed could be altered by the substituent on the nitrogen atom. This allows one to prepare a combinatorial library of azamacrolides from a small number of hydroxy-azaesters using this biocatalytic approach.en_US
dc.languageengen_US
dc.publisherPergamon. The Journal's web site is located at http://www.elsevier.com/locate/tetleten_US
dc.relation.ispartofTetrahedron Lettersen_US
dc.titleChemoenzymatic synthesis of macrocyclic polyaminesen_US
dc.typeArticleen_US
dc.identifier.emailLu, W:luwei@hku.hken_US
dc.identifier.authorityLu, W=rp00754en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1016/S0040-4039(99)00954-5en_US
dc.identifier.scopuseid_2-s2.0-0033516518en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0033516518&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume40en_US
dc.identifier.issue27en_US
dc.identifier.spage4965en_US
dc.identifier.epage4968en_US
dc.identifier.isiWOS:000081122400012-
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridLu, W=27868087600en_US
dc.identifier.scopusauthoridSih, CJ=7006959021en_US
dc.identifier.issnl0040-4039-

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