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Article: Gold(III) porphyrins as a new class of anticancer drugs: Cytotoxicity, DNA binding and induction of apoptosis in human cervix epitheloid cancer cells

TitleGold(III) porphyrins as a new class of anticancer drugs: Cytotoxicity, DNA binding and induction of apoptosis in human cervix epitheloid cancer cells
Authors
Che, CMSun, RWYYu, WYKo, CBZhu, NSun, H
Issue Date2003
PublisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp
Citation
Chemical Communications, 2003, v. 9 n. 14, p. 1718-1719 How to Cite?
DOI: http://dx.doi.org/10.1039/B303294A
AbstractA series of gold(III) tetraarylporphyrins are stable in the presence of glutathione and exert much higher potency than cisplatin in killing human cancer cells, including the drug-resistant variants; the gold-induced cytotoxicity occurs through an apoptotic pathway according to laser confocal microscopy and flow cytometric studies.
Persistent Identifierhttp://hdl.handle.net/10722/167802
ISSN
1359-7345
2021 Impact Factor: 6.065
2020 SCImago Journal Rankings: 1.837
ISI Accession Number ID
WOS:000183872700050
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorChe, CMen_HK
dc.contributor.authorSun, RWYen_HK
dc.contributor.authorYu, WYen_HK
dc.contributor.authorKo, CBen_HK
dc.contributor.authorZhu, Nen_HK
dc.contributor.authorSun, Hen_HK
dc.date.accessioned2012-10-08T03:11:47Z-
dc.date.available2012-10-08T03:11:47Z-
dc.date.issued2003en_HK
dc.identifier.citationChemical Communications, 2003, v. 9 n. 14, p. 1718-1719en_HK
dc.identifier.issn1359-7345en_HK
dc.identifier.urihttp://hdl.handle.net/10722/167802-
dc.description.abstractA series of gold(III) tetraarylporphyrins are stable in the presence of glutathione and exert much higher potency than cisplatin in killing human cancer cells, including the drug-resistant variants; the gold-induced cytotoxicity occurs through an apoptotic pathway according to laser confocal microscopy and flow cytometric studies.en_HK
dc.languageengen_US
dc.publisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.aspen_HK
dc.relation.ispartofChemical Communicationsen_HK
dc.titleGold(III) porphyrins as a new class of anticancer drugs: Cytotoxicity, DNA binding and induction of apoptosis in human cervix epitheloid cancer cellsen_HK
dc.typeArticleen_HK
dc.identifier.emailChe, CM: cmche@hku.hken_HK
dc.identifier.emailSun, RWY: rwysun@hku.hken_HK
dc.identifier.emailZhu, N: nzhu@hkucc.hku.hken_HK
dc.identifier.emailSun, H: hsun@hku.hken_HK
dc.identifier.authorityChe, CM=rp00670en_HK
dc.identifier.authoritySun, RWY=rp00781en_HK
dc.identifier.authorityZhu, N=rp00845en_HK
dc.identifier.authoritySun, H=rp00777en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1039/B303294A-
dc.identifier.pmid12877519-
dc.identifier.scopuseid_2-s2.0-0038639859en_HK
dc.identifier.hkuros90965-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-0038639859&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume9en_HK
dc.identifier.issue14en_HK
dc.identifier.spage1718en_HK
dc.identifier.epage1719en_HK
dc.identifier.isiWOS:000183872700050-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridChe, CM=7102442791en_HK
dc.identifier.scopusauthoridSun, RWY=26325835800en_HK
dc.identifier.scopusauthoridYu, WY=7403913673en_HK
dc.identifier.scopusauthoridKo, CB=7202596810en_HK
dc.identifier.scopusauthoridZhu, N=7201449530en_HK
dc.identifier.scopusauthoridSun, H=7404827446en_HK
dc.identifier.issnl1359-7345-

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