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Article: Na+,K+-ATPase inhibitors and the adrenergic neuroeffector interaction in the blood vessel wall

TitleNa+,K+-ATPase inhibitors and the adrenergic neuroeffector interaction in the blood vessel wall
Authors
Vanhoutte, PMLorenz, RR
KeywordsAcetylstrophanthidin
Cardenolides
Endothelium
Exocytotic release
Monoamine oxidase
Na+, K +-ATPase
Neuronal uptake
Norepinephrine
Ouabain
Postjunctional α-adrenoceptors
Issue Date1984
PublisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.cardiovascularpharm.com/
Citation
Journal Of Cardiovascular Pharmacology, 1984, v. 6 SUPPL. 1, p. S88-S94 How to Cite?
DOI: http://dx.doi.org/10.1097/00005344-198400061-00016
AbstractAugmentation of the constrictor response of blood vessels to sympathetic nerve stimulation caused by inhibitors of Na+,K+-ATPase can be explained by (a) inhibition of neuronal uptake, (b) displacement of stored norepinephrine, (c) facilitation of exocytotic release of the adrenergic transmitter, (d) diminution in intraneuronal deamination, (e) reduction in extraneuronal uptake, (f) facilitation of postjunctional α2-adrenoceptors, (g) inhibition of poststimulation relaxation, and, possibly, (h) prevention of endothelium-dependent relaxation.
Persistent Identifierhttp://hdl.handle.net/10722/170739
ISSN
0160-2446
2021 Impact Factor: 3.271
2020 SCImago Journal Rankings: 0.762
ISI Accession Number ID
WOS:A1984SW38000015

 

DC FieldValueLanguage
dc.contributor.authorVanhoutte, PMen_US
dc.contributor.authorLorenz, RRen_US
dc.date.accessioned2012-10-30T06:10:39Z-
dc.date.available2012-10-30T06:10:39Z-
dc.date.issued1984en_US
dc.identifier.citationJournal Of Cardiovascular Pharmacology, 1984, v. 6 SUPPL. 1, p. S88-S94en_US
dc.identifier.issn0160-2446en_US
dc.identifier.urihttp://hdl.handle.net/10722/170739-
dc.description.abstractAugmentation of the constrictor response of blood vessels to sympathetic nerve stimulation caused by inhibitors of Na+,K+-ATPase can be explained by (a) inhibition of neuronal uptake, (b) displacement of stored norepinephrine, (c) facilitation of exocytotic release of the adrenergic transmitter, (d) diminution in intraneuronal deamination, (e) reduction in extraneuronal uptake, (f) facilitation of postjunctional α2-adrenoceptors, (g) inhibition of poststimulation relaxation, and, possibly, (h) prevention of endothelium-dependent relaxation.en_US
dc.languageengen_US
dc.publisherLippincott Williams & Wilkins. The Journal's web site is located at http://www.cardiovascularpharm.com/en_US
dc.relation.ispartofJournal of Cardiovascular Pharmacologyen_US
dc.subjectAcetylstrophanthidin-
dc.subjectCardenolides-
dc.subjectEndothelium-
dc.subjectExocytotic release-
dc.subjectMonoamine oxidase-
dc.subjectNa+, K +-ATPase-
dc.subjectNeuronal uptake-
dc.subjectNorepinephrine-
dc.subjectOuabain-
dc.subjectPostjunctional α-adrenoceptors-
dc.subject.meshAnimalsen_US
dc.subject.meshDinoprosten_US
dc.subject.meshDogsen_US
dc.subject.meshEndothelium - Drug Effectsen_US
dc.subject.meshHydroxydopamines - Pharmacologyen_US
dc.subject.meshMuscle Relaxation - Drug Effectsen_US
dc.subject.meshMuscle, Smooth, Vascular - Innervation - Physiologyen_US
dc.subject.meshNeuroeffector Junction - Drug Effectsen_US
dc.subject.meshNeurons - Metabolismen_US
dc.subject.meshNeurotransmitter Agents - Physiologyen_US
dc.subject.meshNorepinephrine - Metabolismen_US
dc.subject.meshOuabain - Pharmacologyen_US
dc.subject.meshOxidopamineen_US
dc.subject.meshProstaglandins F - Pharmacologyen_US
dc.subject.meshReceptors, Adrenergic, Alpha - Drug Effectsen_US
dc.subject.meshSodium-Potassium-Exchanging Atpase - Antagonists & Inhibitorsen_US
dc.subject.meshStrophanthidin - Analogs & Derivatives - Pharmacologyen_US
dc.subject.meshSympathectomy, Chemicalen_US
dc.subject.meshSympathetic Nervous System - Drug Effectsen_US
dc.titleNa+,K+-ATPase inhibitors and the adrenergic neuroeffector interaction in the blood vessel wallen_US
dc.typeArticleen_US
dc.identifier.emailVanhoutte, PM:vanhoutt@hku.hken_US
dc.identifier.authorityVanhoutte, PM=rp00238en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.doi10.1097/00005344-198400061-00016-
dc.identifier.pmid6204164-
dc.identifier.scopuseid_2-s2.0-0021253503en_US
dc.identifier.volume6en_US
dc.identifier.issueSUPPL. 1en_US
dc.identifier.spageS88en_US
dc.identifier.epageS94en_US
dc.identifier.isiWOS:A1984SW38000015-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridVanhoutte, PM=7202304247en_US
dc.identifier.scopusauthoridLorenz, RR=7402095192en_US
dc.identifier.issnl0160-2446-

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