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Conference Paper: Dissecting the gender disparity of hepatocellular carcinoma: roles of HBV X protein and androgen receptor

TitleDissecting the gender disparity of hepatocellular carcinoma: roles of HBV X protein and androgen receptor
Authors
KeywordsMedical sciences
Oncology
Issue Date2013
PublisherAmerican Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/
Citation
The 104th Annual Meeting of the American Association for Cancer Research (AACR 2013), Washington, DC., 6-10 April 2013. In Cancer Research, 2013, v. 73 n. 8 suppl. 1, abstract no. 4778 How to Cite?
AbstractHepatocellular carcinoma (HCC) is a leading cancer worldwide and especially prevalent in Southeast Asia, due to prevalent hepatitis B virus (HBV) infection. HBV-associated HCC has a male predominance, with a male-to-female ratio of about 4-5:1. HBV is a partially double-stranded DNA virus containing four overlapping open reading frames. Among them, X gene is most frequently integrated into host genome naturally and plays an important role in hepatocarcinogenesis. In male HBV carriers, the risk of HCC development is significantly increased in those with higher serum androgen and androgen receptor (AR) activity. HBV infection may, therefore, particularly cooperate with male-specific AR signalling to accelerate hepatocarcinogenesis. In this study, we ...
DescriptionConference Theme: Personalizing Cancer Care Through Discovery Science
Poster Session 7 - Transformation and Promotion: abstract no. 4778
This journal suppl. entitled: Proceedings: AACR 104th Annual Meeting ... 2013
Persistent Identifierhttp://hdl.handle.net/10722/186892
ISSN
2021 Impact Factor: 13.312
2020 SCImago Journal Rankings: 4.103
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChiu, YTen_US
dc.contributor.authorNg, IOL-
dc.date.accessioned2013-08-20T12:23:36Z-
dc.date.available2013-08-20T12:23:36Z-
dc.date.issued2013en_US
dc.identifier.citationThe 104th Annual Meeting of the American Association for Cancer Research (AACR 2013), Washington, DC., 6-10 April 2013. In Cancer Research, 2013, v. 73 n. 8 suppl. 1, abstract no. 4778en_US
dc.identifier.issn0008-5472-
dc.identifier.urihttp://hdl.handle.net/10722/186892-
dc.descriptionConference Theme: Personalizing Cancer Care Through Discovery Science-
dc.descriptionPoster Session 7 - Transformation and Promotion: abstract no. 4778-
dc.descriptionThis journal suppl. entitled: Proceedings: AACR 104th Annual Meeting ... 2013-
dc.description.abstractHepatocellular carcinoma (HCC) is a leading cancer worldwide and especially prevalent in Southeast Asia, due to prevalent hepatitis B virus (HBV) infection. HBV-associated HCC has a male predominance, with a male-to-female ratio of about 4-5:1. HBV is a partially double-stranded DNA virus containing four overlapping open reading frames. Among them, X gene is most frequently integrated into host genome naturally and plays an important role in hepatocarcinogenesis. In male HBV carriers, the risk of HCC development is significantly increased in those with higher serum androgen and androgen receptor (AR) activity. HBV infection may, therefore, particularly cooperate with male-specific AR signalling to accelerate hepatocarcinogenesis. In this study, we ...-
dc.languageengen_US
dc.publisherAmerican Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/-
dc.relation.ispartofCancer Researchen_US
dc.subjectMedical sciences-
dc.subjectOncology-
dc.titleDissecting the gender disparity of hepatocellular carcinoma: roles of HBV X protein and androgen receptoren_US
dc.typeConference_Paperen_US
dc.identifier.emailChiu, YT: eytchiu@hku.hken_US
dc.identifier.emailNg, IOL: iolng@hku.hk-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1158/1538-7445.AM2013-4778-
dc.identifier.hkuros218413en_US
dc.identifier.volume73-
dc.identifier.issue8 suppl. 1-
dc.identifier.isiWOS:000331220604341-
dc.publisher.placeUnited States-
dc.identifier.issnl0008-5472-

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