File Download
Supplementary
-
Citations:
- Appears in Collections:
Conference Paper: Nitric oxide/Caveolin-1/MMP pathway: a novel therapeutic strategy for drug discovery from herbal medicine targeting blood-brain-barrier disruption during cerebral Ischemia-reperfusion injury
| Title | Nitric oxide/Caveolin-1/MMP pathway: a novel therapeutic strategy for drug discovery from herbal medicine targeting blood-brain-barrier disruption during cerebral Ischemia-reperfusion injury |
|---|---|
| Authors | |
| Issue Date | 2013 |
| Publisher | International Joint Conference of ICM-PCMCAIM |
| Citation | The 2013 Joint Congress for International Conference for Microcirculation and the 13th Annual Conference of the Professional Committee for Microcirculation, Chinese Association of Integrative Medicine (ICM-PCMCAIM), Beijing, China, 6-8 September 2013. How to Cite? |
| Abstract | AIMS: Blood-brain-barrier (BBB) disruption is a crucial process in stroke, but no effective drug is available. Thus, drug discovery targeting BBB permeability becomes timely important. In this study, we hypothesized that Nitric oxide (NO)/Cav-1/Matrix metalloproteinase (MMP) pathway is important therapeutic targets in preventing BBB disruption. Following, we investigated the effects of CG, an active compound isolated from Astragali Radix on regulating this pathway and protecting BBB permeability and brain damage during cerebral ischemia-reperfusion injury. METHODS: SD rats were subject to ... |
| Description | Symposium 1 - Permeability: no. S1-2 |
| Persistent Identifier | http://hdl.handle.net/10722/201703 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Shen, J | en_US |
| dc.contributor.author | Gu, Y | - |
| dc.contributor.author | Liu, KJ | - |
| dc.date.accessioned | 2014-08-21T07:37:37Z | - |
| dc.date.available | 2014-08-21T07:37:37Z | - |
| dc.date.issued | 2013 | en_US |
| dc.identifier.citation | The 2013 Joint Congress for International Conference for Microcirculation and the 13th Annual Conference of the Professional Committee for Microcirculation, Chinese Association of Integrative Medicine (ICM-PCMCAIM), Beijing, China, 6-8 September 2013. | en_US |
| dc.identifier.uri | http://hdl.handle.net/10722/201703 | - |
| dc.description | Symposium 1 - Permeability: no. S1-2 | - |
| dc.description.abstract | AIMS: Blood-brain-barrier (BBB) disruption is a crucial process in stroke, but no effective drug is available. Thus, drug discovery targeting BBB permeability becomes timely important. In this study, we hypothesized that Nitric oxide (NO)/Cav-1/Matrix metalloproteinase (MMP) pathway is important therapeutic targets in preventing BBB disruption. Following, we investigated the effects of CG, an active compound isolated from Astragali Radix on regulating this pathway and protecting BBB permeability and brain damage during cerebral ischemia-reperfusion injury. METHODS: SD rats were subject to ... | - |
| dc.language | eng | en_US |
| dc.publisher | International Joint Conference of ICM-PCMCAIM | - |
| dc.relation.ispartof | ICM-PCMCAIM 2013 | en_US |
| dc.relation.ispartof | 2013微循环国际研讨会暨第十三届全国中西医结合微循环学术会议 | - |
| dc.title | Nitric oxide/Caveolin-1/MMP pathway: a novel therapeutic strategy for drug discovery from herbal medicine targeting blood-brain-barrier disruption during cerebral Ischemia-reperfusion injury | en_US |
| dc.type | Conference_Paper | en_US |
| dc.identifier.email | Shen, J: shenjg@hku.hk | en_US |
| dc.identifier.authority | Shen, J=rp00487 | en_US |
| dc.description.nature | postprint | - |
| dc.identifier.hkuros | 233605 | en_US |
| dc.publisher.place | China | - |