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Article: Little girl who conquered the 'ALPPS'
Title | Little girl who conquered the 'ALPPS' |
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Authors | |
Keywords | Hepatoblastoma In-situ split Associating liver partition and portal vein ligation for stage hepatectomy Portal vein Hepatectomy |
Issue Date | 2014 |
Publisher | Baishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htm |
Citation | World Journal of Gastroenterology, 2014, v. 20 n. 29, p. 10208-10211 How to Cite? |
Abstract | © 2014 Baishideng Publishing Group Inc. All rights reserved. An insufficient future liver remnant (FLR) is associated with post-hepatectomy liver failure. Associating liver partition and portal vein ligation for stage hepatectomy (ALPPS) has been shown to be effective for the induction of rapid FLR hypertrophy so as to improve the resectability in patients with insufficient FLR. We hereby report our experience of this novel approach for a 6-year-old patient with hepatoblastoma. Computed tomography showed a hepatoblastoma measuring 12.5 cm x 9.9 cm x 11.7 cm in the right liver (Couinaud segment IV, V and VIII). Volumetric assessment of the FLR i.e., left lateral section was 112.6 mL i.e., 21.2% of the estimated total liver volume. In view of the small-for-size FLR, ALPPS was contemplated. An anterior approach was adopted for the in-situ parenchymal split without mobilisation of the right liver. FLR volumetry on the seventh postoperative day was 160.7 mL, which represented a 46.1% gain in volume, and a FLR/ESLV ratio of 30.2%. A right trisectionectomy was performed on the eighth postoperative day. Postoperative recovery was uneventful. Patient was discharged on day 16 after the first operation. To our knowledge, this was the first report that showed the applicability of ALPPS to a paediatric patient. |
Persistent Identifier | http://hdl.handle.net/10722/205971 |
ISSN | 2021 Impact Factor: 5.374 2020 SCImago Journal Rankings: 1.427 |
PubMed Central ID | |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Chan, ACY | en_US |
dc.contributor.author | Chung, HY | en_US |
dc.contributor.author | Poon, RTP | en_US |
dc.date.accessioned | 2014-10-20T10:37:59Z | - |
dc.date.available | 2014-10-20T10:37:59Z | - |
dc.date.issued | 2014 | en_US |
dc.identifier.citation | World Journal of Gastroenterology, 2014, v. 20 n. 29, p. 10208-10211 | en_US |
dc.identifier.issn | 1007-9327 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/205971 | - |
dc.description.abstract | © 2014 Baishideng Publishing Group Inc. All rights reserved. An insufficient future liver remnant (FLR) is associated with post-hepatectomy liver failure. Associating liver partition and portal vein ligation for stage hepatectomy (ALPPS) has been shown to be effective for the induction of rapid FLR hypertrophy so as to improve the resectability in patients with insufficient FLR. We hereby report our experience of this novel approach for a 6-year-old patient with hepatoblastoma. Computed tomography showed a hepatoblastoma measuring 12.5 cm x 9.9 cm x 11.7 cm in the right liver (Couinaud segment IV, V and VIII). Volumetric assessment of the FLR i.e., left lateral section was 112.6 mL i.e., 21.2% of the estimated total liver volume. In view of the small-for-size FLR, ALPPS was contemplated. An anterior approach was adopted for the in-situ parenchymal split without mobilisation of the right liver. FLR volumetry on the seventh postoperative day was 160.7 mL, which represented a 46.1% gain in volume, and a FLR/ESLV ratio of 30.2%. A right trisectionectomy was performed on the eighth postoperative day. Postoperative recovery was uneventful. Patient was discharged on day 16 after the first operation. To our knowledge, this was the first report that showed the applicability of ALPPS to a paediatric patient. | - |
dc.language | eng | en_US |
dc.publisher | Baishideng Publishing Group. The Journal's web site is located at http://www.wjgnet.com/1007-9327/index.htm | en_US |
dc.relation.ispartof | World Journal of Gastroenterology | en_US |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. | - |
dc.subject | Hepatoblastoma | - |
dc.subject | In-situ split | - |
dc.subject | Associating liver partition and portal vein ligation for stage hepatectomy | - |
dc.subject | Portal vein | - |
dc.subject | Hepatectomy | - |
dc.title | Little girl who conquered the 'ALPPS' | en_US |
dc.type | Article | en_US |
dc.identifier.email | Chan, ACY: acchan@hku.hk | en_US |
dc.identifier.email | Poon, RTP: poontp@hku.hk | en_US |
dc.identifier.authority | Chan, ACY=rp00310 | en_US |
dc.identifier.authority | Chung, HY=rp02002 | en_US |
dc.description.nature | published_or_final_version | - |
dc.identifier.doi | 10.3748/wjg.v20.i29.10208 | - |
dc.identifier.pmid | 25110450 | - |
dc.identifier.pmcid | PMC4123352 | - |
dc.identifier.scopus | eid_2-s2.0-84905845193 | - |
dc.identifier.hkuros | 240827 | en_US |
dc.identifier.volume | 20 | en_US |
dc.identifier.issue | 29 | en_US |
dc.identifier.spage | 10208 | en_US |
dc.identifier.epage | 10211 | en_US |
dc.identifier.isi | WOS:000340730300047 | - |
dc.publisher.place | China | en_US |
dc.identifier.issnl | 1007-9327 | - |