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Conference Paper: Differential long non-coding RNA expressions in gliomas with EGFR alteration

TitleDifferential long non-coding RNA expressions in gliomas with EGFR alteration
Authors
Kiang, KMYZhang, XLeung, GKK
Issue Date2015
Citation
The 2015 Conjoint Annual Scientific Meeting (ASM) of the Hong Kong Neurosurgical Society (HKNS), Hong Kong, 20-21 November 2015. How to Cite?
AbstractBACKGROUND: Epidermal growth factor receptor (EGFR) is frequently overexpressed and mutated in various types of malignancies. In glioblastoma multiforme (GBM), the most aggressive form of brain tumor, EGFRvIII is the most common deletion mutant of EGFR that leads to its constant activation. Both EGFR amplification and EGFRvIII mutation have been associated with poorer prognosis in GBM patients, however, the downstream effects of this EGFR over-activity remains incompletely understood. Long non-coding RNAs (lncRNAs) are emerging as important regulators in different types of cancers. Given that we have previously ...
DescriptionConference Theme: Brain Attack: A New Era
Posters: no. P-13
Persistent Identifierhttp://hdl.handle.net/10722/222051

 

DC FieldValueLanguage
dc.contributor.authorKiang, KMY-
dc.contributor.authorZhang, X-
dc.contributor.authorLeung, GKK-
dc.date.accessioned2015-12-21T05:53:57Z-
dc.date.available2015-12-21T05:53:57Z-
dc.date.issued2015-
dc.identifier.citationThe 2015 Conjoint Annual Scientific Meeting (ASM) of the Hong Kong Neurosurgical Society (HKNS), Hong Kong, 20-21 November 2015.-
dc.identifier.urihttp://hdl.handle.net/10722/222051-
dc.descriptionConference Theme: Brain Attack: A New Era-
dc.descriptionPosters: no. P-13-
dc.description.abstractBACKGROUND: Epidermal growth factor receptor (EGFR) is frequently overexpressed and mutated in various types of malignancies. In glioblastoma multiforme (GBM), the most aggressive form of brain tumor, EGFRvIII is the most common deletion mutant of EGFR that leads to its constant activation. Both EGFR amplification and EGFRvIII mutation have been associated with poorer prognosis in GBM patients, however, the downstream effects of this EGFR over-activity remains incompletely understood. Long non-coding RNAs (lncRNAs) are emerging as important regulators in different types of cancers. Given that we have previously ...-
dc.languageeng-
dc.relation.ispartofHKNS Conjoint Annual Scientific Meeting, ASM 2015-
dc.titleDifferential long non-coding RNA expressions in gliomas with EGFR alteration-
dc.typeConference_Paper-
dc.identifier.emailLeung, GKK: gkkleung@hku.hk-
dc.identifier.authorityLeung, GKK=rp00522-
dc.description.naturepostprint-
dc.identifier.hkuros256334-

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