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Conference Paper: Pharmacological Inactivation of Dorsal Hippocampus Enhances Responses and Induces Adaptation to Sound in Midbrain.
| Title | Pharmacological Inactivation of Dorsal Hippocampus Enhances Responses and Induces Adaptation to Sound in Midbrain. |
|---|---|
| Authors | |
| Issue Date | 2017 |
| Publisher | The International Society for Magnetic Resonance in Medicine. |
| Citation | The International Society of Magnetic Resonance in Medicine (ISMRM) 25th Annual Meeting & Exhibition, Honolulu, HI, USA, 22-27 April 2017 How to Cite? |
| Abstract | The hippocampus is associated with the memory and learning, meanwhile, receives signal from all sensory system indirectly. However, whether and how the hippocampus influences sound processing in the auditory system remains unclear. Our recent study showed that optogenetic stimulation of hippocampus enhances the brain bilateral auditory cortex connectivity. This fMRI study investigated the influence of hippocampus on auditory processing in the inferior colliculus (IC) by using tetrodotoxin (TTX) to pharmacologically deactivate the dorsal hippocampus. For the first time, our results revealed that the dorsal hippocampus plays a dynamic role in shaping the IC auditory response. |
| Description | Electronic Poster Session: fMRI - Physiology - abstract no. 5310 |
| Persistent Identifier | http://hdl.handle.net/10722/247801 |
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Dong, CM | - |
| dc.contributor.author | Chan, RW | - |
| dc.contributor.author | Ho, LCC | - |
| dc.contributor.author | Leong, ATL | - |
| dc.contributor.author | Wong, ECS | - |
| dc.contributor.author | Wang, L | - |
| dc.contributor.author | Chen, FF | - |
| dc.contributor.author | Lau, C | - |
| dc.contributor.author | Wu, EX | - |
| dc.date.accessioned | 2017-10-18T08:32:53Z | - |
| dc.date.available | 2017-10-18T08:32:53Z | - |
| dc.date.issued | 2017 | - |
| dc.identifier.citation | The International Society of Magnetic Resonance in Medicine (ISMRM) 25th Annual Meeting & Exhibition, Honolulu, HI, USA, 22-27 April 2017 | - |
| dc.identifier.uri | http://hdl.handle.net/10722/247801 | - |
| dc.description | Electronic Poster Session: fMRI - Physiology - abstract no. 5310 | - |
| dc.description.abstract | The hippocampus is associated with the memory and learning, meanwhile, receives signal from all sensory system indirectly. However, whether and how the hippocampus influences sound processing in the auditory system remains unclear. Our recent study showed that optogenetic stimulation of hippocampus enhances the brain bilateral auditory cortex connectivity. This fMRI study investigated the influence of hippocampus on auditory processing in the inferior colliculus (IC) by using tetrodotoxin (TTX) to pharmacologically deactivate the dorsal hippocampus. For the first time, our results revealed that the dorsal hippocampus plays a dynamic role in shaping the IC auditory response. | - |
| dc.language | eng | - |
| dc.publisher | The International Society for Magnetic Resonance in Medicine. | - |
| dc.relation.ispartof | ISMRM 2017 Annual Meeting & Exhibition | - |
| dc.title | Pharmacological Inactivation of Dorsal Hippocampus Enhances Responses and Induces Adaptation to Sound in Midbrain. | - |
| dc.type | Conference_Paper | - |
| dc.identifier.email | Chan, RW: russchan@connect.hku.hk | - |
| dc.identifier.email | Leong, ATL: tlleong@hku.hk | - |
| dc.identifier.email | Wu, EX: ewu@eee.hku.hk | - |
| dc.identifier.authority | Wu, EX=rp00193 | - |
| dc.identifier.hkuros | 280421 | - |
| dc.publisher.place | United States | - |