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Article: A new chemical approach for proximity labelling of chromatin-associated RNAs and proteins with visible light irradiation

TitleA new chemical approach for proximity labelling of chromatin-associated RNAs and proteins with visible light irradiation
Authors
Issue Date2019
PublisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp
Citation
Chemical Communications, 2019, v. 55 n. 82, p. 12340-12343 How to Cite?
AbstractA new nucleus-localized singlet oxygen generator was designed and synthesized. Its capability to label nucleus-localized biomolecules through spatially-restricted oxidation under visible light was validated using fluorescence confocal microscopy. Western blot and RT-qPCR were performed to verify the desirable spatial resolution through enriching chromatin-associated RNAs and proteins.
Persistent Identifierhttp://hdl.handle.net/10722/279289
ISSN
2019 Impact Factor: 5.996
2015 SCImago Journal Rankings: 2.771

 

DC FieldValueLanguage
dc.contributor.authorLi, L-
dc.contributor.authorLiang, J-
dc.contributor.authorLuo, H-
dc.contributor.authorTam, KM-
dc.contributor.authorTse, CME-
dc.contributor.authorLi, Y-
dc.date.accessioned2019-10-25T01:51:07Z-
dc.date.available2019-10-25T01:51:07Z-
dc.date.issued2019-
dc.identifier.citationChemical Communications, 2019, v. 55 n. 82, p. 12340-12343-
dc.identifier.issn1359-7345-
dc.identifier.urihttp://hdl.handle.net/10722/279289-
dc.description.abstractA new nucleus-localized singlet oxygen generator was designed and synthesized. Its capability to label nucleus-localized biomolecules through spatially-restricted oxidation under visible light was validated using fluorescence confocal microscopy. Western blot and RT-qPCR were performed to verify the desirable spatial resolution through enriching chromatin-associated RNAs and proteins.-
dc.languageeng-
dc.publisherRoyal Society of Chemistry. The Journal's web site is located at http://www.rsc.org/Publishing/Journals/cc/index.asp-
dc.relation.ispartofChemical Communications-
dc.titleA new chemical approach for proximity labelling of chromatin-associated RNAs and proteins with visible light irradiation-
dc.typeArticle-
dc.identifier.emailLuo, H: lawhao@HKUCC.hku.hk-
dc.identifier.emailTse, CME: ecmtse@hku.hk-
dc.identifier.emailLi, Y: yingli0e@hku.hk-
dc.identifier.authorityTse, CME=rp02452-
dc.identifier.authorityLi, Y=rp02548-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1039/C9CC06251C-
dc.identifier.scopuseid_2-s2.0-85073125719-
dc.identifier.hkuros307324-
dc.identifier.volume55-
dc.identifier.issue82-
dc.identifier.spage12340-
dc.identifier.epage12343-
dc.publisher.placeUnited Kingdom-

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