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Article: Toxicity outcome of endorectal brachytherapy boost in medically inoperable patients

TitleToxicity outcome of endorectal brachytherapy boost in medically inoperable patients
Authors
KeywordsHigh dose rate endorectal brachytherapy
Rectal cancer
Medically inoperable
Toxicity
Rectal brachytherapy
Issue Date2020
PublisherSpringer Medizin. The Journal's web site is located at http://www.springer.com/medicine/radiology/journal/66
Citation
Strahlentherapie und Onkologie: Zeitschrift fuer Radiologie, Strahlenbiologie, Strahlenphysik, 2020, Epub on 2020-04-20 How to Cite?
AbstractAim: This communication reviews results and toxicity of image-guided high-dose-rate endorectal brachytherapy (HDREBT) boost after external beam radiotherapy (ERT) in medically inoperable patients with rectal cancer. Materials and methods: A total of 18 patients with rectal cancer and clinical stage T2-4N0‑2 treated with HDREBT boost after ERT were retrospectively reviewed. Results: Following treatment with a median total dose (EQD2, α/β = 10) of 66 Gy (range 48–92 Gy), the incidence of early and late rectal grade 3 toxicity was 11% and 19%, respectively. There was no correlation between the occurrence of acute and late toxicity. Conclusion: With proper technique, a combined approach using EBRT and HDREBT was associated with acceptable toxicity in medically inoperable rectal cancer patients.
Persistent Identifierhttp://hdl.handle.net/10722/282523
ISSN
2019 Impact Factor: 2.899
2015 SCImago Journal Rankings: 1.069
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorChiang, CL-
dc.contributor.authorLee, SF-
dc.contributor.authorLee, VWY-
dc.contributor.authorYeung, CSY-
dc.contributor.authorCheung, SKT-
dc.contributor.authorPoon, MCM-
dc.contributor.authorFoo, DCC-
dc.contributor.authorLo, SH-
dc.contributor.authorLam, KO-
dc.contributor.authorLee, FAS-
dc.contributor.authorWong, FCS-
dc.contributor.authorChan, MKH-
dc.date.accessioned2020-05-15T05:29:13Z-
dc.date.available2020-05-15T05:29:13Z-
dc.date.issued2020-
dc.identifier.citationStrahlentherapie und Onkologie: Zeitschrift fuer Radiologie, Strahlenbiologie, Strahlenphysik, 2020, Epub on 2020-04-20-
dc.identifier.issn0179-7158-
dc.identifier.urihttp://hdl.handle.net/10722/282523-
dc.description.abstractAim: This communication reviews results and toxicity of image-guided high-dose-rate endorectal brachytherapy (HDREBT) boost after external beam radiotherapy (ERT) in medically inoperable patients with rectal cancer. Materials and methods: A total of 18 patients with rectal cancer and clinical stage T2-4N0‑2 treated with HDREBT boost after ERT were retrospectively reviewed. Results: Following treatment with a median total dose (EQD2, α/β = 10) of 66 Gy (range 48–92 Gy), the incidence of early and late rectal grade 3 toxicity was 11% and 19%, respectively. There was no correlation between the occurrence of acute and late toxicity. Conclusion: With proper technique, a combined approach using EBRT and HDREBT was associated with acceptable toxicity in medically inoperable rectal cancer patients.-
dc.languageeng-
dc.publisherSpringer Medizin. The Journal's web site is located at http://www.springer.com/medicine/radiology/journal/66-
dc.relation.ispartofStrahlentherapie und Onkologie: Zeitschrift fuer Radiologie, Strahlenbiologie, Strahlenphysik-
dc.rightsThis is a post-peer-review, pre-copyedit version of an article published in [insert journal title]. The final authenticated version is available online at: http://dx.doi.org/[insert DOI]-
dc.subjectHigh dose rate endorectal brachytherapy-
dc.subjectRectal cancer-
dc.subjectMedically inoperable-
dc.subjectToxicity-
dc.subjectRectal brachytherapy-
dc.titleToxicity outcome of endorectal brachytherapy boost in medically inoperable patients-
dc.typeArticle-
dc.identifier.emailChiang, CL: chiangcl@hku.hk-
dc.identifier.emailFoo, DCC: ccfoo@hku.hk-
dc.identifier.emailLo, SH: oswens@hku.hk-
dc.identifier.emailLam, KO: lamkaon@hku.hk-
dc.identifier.authorityChiang, CL=rp02241-
dc.identifier.authorityFoo, DCC=rp01899-
dc.identifier.authorityLam, KO=rp01501-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1007/s00066-020-01612-0-
dc.identifier.pmid32313964-
dc.identifier.scopuseid_2-s2.0-85084066116-
dc.identifier.hkuros309881-
dc.identifier.volumeEpub on 2020-04-20-
dc.identifier.isiWOS:000527457200001-
dc.publisher.placeGermany-

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