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Article: Lutein Supplementation for Eye Diseases

TitleLutein Supplementation for Eye Diseases
Authors
Keywordsage-related macular degeneration
antioxidant
carotenoid
diabetic retinopathy
myopia
Issue Date2020
PublisherMDPI AG. The Journal's web site is located at http://www.mdpi.com/journal/nutrients/
Citation
Nutrients, 2020, v. 12 n. 6, p. article no. 1721 How to Cite?
AbstractLutein is one of the few xanthophyll carotenoids that is found in high concentration in the macula of human retina. As de novo synthesis of lutein within the human body is impossible, lutein can only be obtained from diet. It is a natural substance abundant in egg yolk and dark green leafy vegetables. Many basic and clinical studies have reported lutein’s anti-oxidative and anti-inflammatory properties in the eye, suggesting its beneficial effects on protection and alleviation of ocular diseases such as age-related macular degeneration, diabetic retinopathy, retinopathy of prematurity, myopia, and cataract. Most importantly, lutein is categorized as Generally Regarded as Safe (GRAS), posing minimal side-effects upon long term consumption. In this review, we will discuss the chemical structure and properties of lutein as well as its application and safety as a nutritional supplement. Finally, the effects of lutein consumption on the aforementioned eye diseases will be reviewed.
Persistent Identifierhttp://hdl.handle.net/10722/283242
ISSN
2018 Impact Factor: 4.171
2015 SCImago Journal Rankings: 2.275
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorLi, LH-
dc.contributor.authorLee, JCY-
dc.contributor.authorLEUNG, HH-
dc.contributor.authorLam, WC-
dc.contributor.authorFu, Z-
dc.contributor.authorLo, ACY-
dc.date.accessioned2020-06-22T02:54:01Z-
dc.date.available2020-06-22T02:54:01Z-
dc.date.issued2020-
dc.identifier.citationNutrients, 2020, v. 12 n. 6, p. article no. 1721-
dc.identifier.issn2072-6643-
dc.identifier.urihttp://hdl.handle.net/10722/283242-
dc.description.abstractLutein is one of the few xanthophyll carotenoids that is found in high concentration in the macula of human retina. As de novo synthesis of lutein within the human body is impossible, lutein can only be obtained from diet. It is a natural substance abundant in egg yolk and dark green leafy vegetables. Many basic and clinical studies have reported lutein’s anti-oxidative and anti-inflammatory properties in the eye, suggesting its beneficial effects on protection and alleviation of ocular diseases such as age-related macular degeneration, diabetic retinopathy, retinopathy of prematurity, myopia, and cataract. Most importantly, lutein is categorized as Generally Regarded as Safe (GRAS), posing minimal side-effects upon long term consumption. In this review, we will discuss the chemical structure and properties of lutein as well as its application and safety as a nutritional supplement. Finally, the effects of lutein consumption on the aforementioned eye diseases will be reviewed.-
dc.languageeng-
dc.publisherMDPI AG. The Journal's web site is located at http://www.mdpi.com/journal/nutrients/-
dc.relation.ispartofNutrients-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectage-related macular degeneration-
dc.subjectantioxidant-
dc.subjectcarotenoid-
dc.subjectdiabetic retinopathy-
dc.subjectmyopia-
dc.titleLutein Supplementation for Eye Diseases-
dc.typeArticle-
dc.identifier.emailLee, JCY: jettylee@hku.hk-
dc.identifier.emailLam, WC: waichlam@hku.hk-
dc.identifier.emailLo, ACY: amylo@hku.hk-
dc.identifier.authorityLee, JCY=rp01511-
dc.identifier.authorityLam, WC=rp02162-
dc.identifier.authorityLo, ACY=rp00425-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.3390/nu12061721-
dc.identifier.pmid32526861-
dc.identifier.scopuseid_2-s2.0-85086162134-
dc.identifier.hkuros310418-
dc.identifier.volume12-
dc.identifier.issue6-
dc.identifier.spagearticle no. 1721-
dc.identifier.epagearticle no. 1721-
dc.identifier.isiWOS:000549252200001-
dc.publisher.placeSwitzerland-
dc.identifier.issnl2072-6643-

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