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Article: Insights into the ecological roles and evolution of methyl-coenzyme M reductase-containing hot spring Archaea

TitleInsights into the ecological roles and evolution of methyl-coenzyme M reductase-containing hot spring Archaea
Authors
Keywordsalkane
ammonia
archaeal protein
methane
methyl coenzyme M reductase
Issue Date2019
PublisherNature Research (part of Springer Nature): Fully open access journals. The Journal's web site is located at http://www.nature.com/ncomms/index.html
Citation
Nature Communications, 2019, v. 10 n. 1, p. article no. 4574 How to Cite?
AbstractSeveral recent studies have shown the presence of genes for the key enzyme associated with archaeal methane/alkane metabolism, methyl-coenzyme M reductase (Mcr), in metagenome-assembled genomes (MAGs) divergent to existing archaeal lineages. Here, we study the mcr-containing archaeal MAGs from several hot springs, which reveal further expansion in the diversity of archaeal organisms performing methane/alkane metabolism. Significantly, an MAG basal to organisms from the phylum Thaumarchaeota that contains mcr genes, but not those for ammonia oxidation or aerobic metabolism, is identified. Together, our phylogenetic analyses and ancestral state reconstructions suggest a mostly vertical evolution of mcrABG genes among methanogens and methanotrophs, along with frequent horizontal gene transfer of mcr genes between alkanotrophs. Analysis of all mcr-containing archaeal MAGs/genomes suggests a hydrothermal origin for these microorganisms based on optimal growth temperature predictions. These results also suggest methane/alkane oxidation or methanogenesis at high temperature likely existed in a common archaeal ancestor.
Persistent Identifierhttp://hdl.handle.net/10722/286045
ISSN
2019 Impact Factor: 12.121
2015 SCImago Journal Rankings: 6.539
PubMed Central ID

 

DC FieldValueLanguage
dc.contributor.authorHua, ZS-
dc.contributor.authorWang, YL-
dc.contributor.authorEvans, PN-
dc.contributor.authorQu, YN-
dc.contributor.authorGoh, KM-
dc.contributor.authorRao, Y-
dc.contributor.authorQi, YZ-
dc.contributor.authorLi, YL-
dc.contributor.authorHuang, MJ-
dc.contributor.authorJiao, JY-
dc.contributor.authorChen, YT-
dc.contributor.authorMao, YP-
dc.contributor.authorShu, WS-
dc.contributor.authorWael, H-
dc.contributor.authorHedlund, BP-
dc.contributor.authorTyson, GW-
dc.contributor.authorZhang, T-
dc.contributor.authorLi, WJ-
dc.date.accessioned2020-08-31T06:58:18Z-
dc.date.available2020-08-31T06:58:18Z-
dc.date.issued2019-
dc.identifier.citationNature Communications, 2019, v. 10 n. 1, p. article no. 4574-
dc.identifier.issn2041-1723-
dc.identifier.urihttp://hdl.handle.net/10722/286045-
dc.description.abstractSeveral recent studies have shown the presence of genes for the key enzyme associated with archaeal methane/alkane metabolism, methyl-coenzyme M reductase (Mcr), in metagenome-assembled genomes (MAGs) divergent to existing archaeal lineages. Here, we study the mcr-containing archaeal MAGs from several hot springs, which reveal further expansion in the diversity of archaeal organisms performing methane/alkane metabolism. Significantly, an MAG basal to organisms from the phylum Thaumarchaeota that contains mcr genes, but not those for ammonia oxidation or aerobic metabolism, is identified. Together, our phylogenetic analyses and ancestral state reconstructions suggest a mostly vertical evolution of mcrABG genes among methanogens and methanotrophs, along with frequent horizontal gene transfer of mcr genes between alkanotrophs. Analysis of all mcr-containing archaeal MAGs/genomes suggests a hydrothermal origin for these microorganisms based on optimal growth temperature predictions. These results also suggest methane/alkane oxidation or methanogenesis at high temperature likely existed in a common archaeal ancestor.-
dc.languageeng-
dc.publisherNature Research (part of Springer Nature): Fully open access journals. The Journal's web site is located at http://www.nature.com/ncomms/index.html-
dc.relation.ispartofNature Communications-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectalkane-
dc.subjectammonia-
dc.subjectarchaeal protein-
dc.subjectmethane-
dc.subjectmethyl coenzyme M reductase-
dc.titleInsights into the ecological roles and evolution of methyl-coenzyme M reductase-containing hot spring Archaea-
dc.typeArticle-
dc.identifier.emailWang, YL: wangyl01@hku.hk-
dc.identifier.emailZhang, T: zhangt@hkucc.hku.hk-
dc.identifier.authorityZhang, T=rp00211-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.1038/s41467-019-12574-y-
dc.identifier.pmid31594929-
dc.identifier.pmcidPMC6783470-
dc.identifier.scopuseid_2-s2.0-85073073609-
dc.identifier.hkuros313161-
dc.identifier.volume10-
dc.identifier.issue1-
dc.identifier.spagearticle no. 4574-
dc.identifier.epagearticle no. 4574-
dc.publisher.placeUnited Kingdom-

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