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Article: Congenital infections in Hong Kong: beyond TORCH

TitleCongenital infections in Hong Kong: beyond TORCH
Authors
Keywordscongenital heart disease
congenital infection
Cytomegalovirus
disease burden
disease surveillance
Issue Date2020
PublisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org/
Citation
Hong Kong Medical Journal, 2020, v. 26, p. 323-330 How to Cite?
AbstractCongenital infections refer to a group of perinatal infections that are caused by pathogens transmitted from mother to child during pregnancy (transplacentally) or delivery (peripartum) which may have similar clinical presentations, including rash and ocular findings. TORCH is the acronym that covers these infections (toxoplasmosis, other [syphilis], rubella, cytomegalovirus, herpes simplex virus). Other important causes of intrauterine/perinatal infection include human immunodeficiency virus, varicella-zoster virus, Treponema pallidum, Zika virus, and parvovirus B19. This overview aims to describe various congenital infections beyond TORCH with a Hong Kong perspective. Intrauterine and perinatal infections are a major cause of in utero death and neonatal mortality, and an important contributor to childhood morbidity. A high index of suspicion for congenital infections and awareness of the prominent features of the most common congenital infections can help to facilitate early diagnosis, tailor appropriate diagnostic evaluation, and initiate appropriate early treatment. Intrauterine infections should be suspected in newborns with clinical features including microcephaly, seizures, cataract, hearing loss, congenital heart disease, hepatosplenomegaly, small for gestational age, and/or rash. Primary prevention of maternal infections during pregnancy is key to the prevention of congenital infection, and resources (if available) should focus on public health promotion and pre-marital counselling.
Persistent Identifierhttp://hdl.handle.net/10722/289465
ISSN
2019 Impact Factor: 1.679
2015 SCImago Journal Rankings: 0.279

 

DC FieldValueLanguage
dc.contributor.authorHon, KL-
dc.contributor.authorLeung, KKY-
dc.contributor.authorLeung, AKC-
dc.contributor.authorMan, E-
dc.contributor.authorIp, P-
dc.date.accessioned2020-10-22T08:13:03Z-
dc.date.available2020-10-22T08:13:03Z-
dc.date.issued2020-
dc.identifier.citationHong Kong Medical Journal, 2020, v. 26, p. 323-330-
dc.identifier.issn1024-2708-
dc.identifier.urihttp://hdl.handle.net/10722/289465-
dc.description.abstractCongenital infections refer to a group of perinatal infections that are caused by pathogens transmitted from mother to child during pregnancy (transplacentally) or delivery (peripartum) which may have similar clinical presentations, including rash and ocular findings. TORCH is the acronym that covers these infections (toxoplasmosis, other [syphilis], rubella, cytomegalovirus, herpes simplex virus). Other important causes of intrauterine/perinatal infection include human immunodeficiency virus, varicella-zoster virus, Treponema pallidum, Zika virus, and parvovirus B19. This overview aims to describe various congenital infections beyond TORCH with a Hong Kong perspective. Intrauterine and perinatal infections are a major cause of in utero death and neonatal mortality, and an important contributor to childhood morbidity. A high index of suspicion for congenital infections and awareness of the prominent features of the most common congenital infections can help to facilitate early diagnosis, tailor appropriate diagnostic evaluation, and initiate appropriate early treatment. Intrauterine infections should be suspected in newborns with clinical features including microcephaly, seizures, cataract, hearing loss, congenital heart disease, hepatosplenomegaly, small for gestational age, and/or rash. Primary prevention of maternal infections during pregnancy is key to the prevention of congenital infection, and resources (if available) should focus on public health promotion and pre-marital counselling.-
dc.languageeng-
dc.publisherHong Kong Academy of Medicine Press. The Journal's web site is located at http://www.hkmj.org/-
dc.relation.ispartofHong Kong Medical Journal-
dc.rightsHong Kong Medical Journal. Copyright © Hong Kong Academy of Medicine Press.-
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.-
dc.subjectcongenital heart disease-
dc.subjectcongenital infection-
dc.subjectCytomegalovirus-
dc.subjectdisease burden-
dc.subjectdisease surveillance-
dc.titleCongenital infections in Hong Kong: beyond TORCH-
dc.typeArticle-
dc.identifier.emailHon, KL: hon@cuhk.edu.hk-
dc.identifier.emailLeung, KKY: kkyleung@hku.hk-
dc.identifier.emailMan, E: elimman@hku.hk-
dc.identifier.emailIp, P: patricip@hku.hk-
dc.identifier.authorityIp, P=rp01337-
dc.description.naturepublished_or_final_version-
dc.identifier.doi10.12809/hkmj208398-
dc.identifier.pmid32705996-
dc.identifier.scopuseid_2-s2.0-85089666665-
dc.identifier.hkuros316033-
dc.identifier.volume26-
dc.identifier.spage323-
dc.identifier.epage330-
dc.publisher.placeHong Kong-

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