File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Milk consumption and risk of mortality from all-cause, cardiovascular disease and cancer in older people

TitleMilk consumption and risk of mortality from all-cause, cardiovascular disease and cancer in older people
Authors
KeywordsMilk consumption
Cardiovascular disease
Cancer
Ischemic heart disease
Stroke
Issue Date2020
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/clnu
Citation
Clinical Nutrition, 2020, v. 39 n. 11, p. 3442-3451 How to Cite?
AbstractBackground: Milk as a common diet is recommended by many guidelines, but the results on the association of milk consumption with the risk of cardiovascular disease (CVD) or cancer were contradictory. Moreover, evidence regarding milk consumption and mortality risk in Chinese is scarce. Objective: We examined the associations of milk consumption with the risk of all-cause, CVD and cancer mortality in a low milk consumption population using data from the Guangzhou Biobank Cohort Study. Design: 18,214 participants aged 50+ years without CVD history at baseline (2003–6) were included. Causes of death were identified through record linkage. Cox proportional hazards regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). Results: Of the 18,214 participants, 12,670 (69.6%) did not consume milk, 2669 (14.7%) had moderate (1–3 portions/week; 1 portion = 250 ml) and 2875 (15.8%) had high (3+ portions/week) consumption. During an average follow-up of 11.5 (standard deviation = 2.3) years, 2697 deaths occurred, including 917 CVD and 1029 cancer deaths. Compared with no consumption, the adjusted HR (95% CIs) of all-cause, CVD, ischemic heart disease (IHD) and stroke mortality for moderate milk consumption was 0.92 (0.81–1.04), 0.72 (0.57–0.92), 0.57 (0.38–0.85) and 0.77 (0.63–0.94), respectively. High consumption was associated with a higher risk of total cancer and esophagus cancer mortality, with the adjusted HR (95% CIs) being 1.33 (1.12–1.57) and 3.20 (1.21–8.43) respectively. No significant association of high consumption with lung cancer, liver cancer, gastrointestinal cancer, or colorectal and anal cancer was found. Conclusions: In our sample of Chinese with much lower milk consumption than those in the West, compared with no consumption, moderate milk consumption showed a lower risk of CVD mortality, but high milk consumption showed a higher risk of total cancer mortality. Further studies are warranted to verify the differential effects of milk on CVD and cancer.
Persistent Identifierhttp://hdl.handle.net/10722/293652
ISSN
2020 Impact Factor: 7.324
2020 SCImago Journal Rankings: 1.915
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorWang, XJ-
dc.contributor.authorJiang, CQ-
dc.contributor.authorZhang, WS-
dc.contributor.authorZhu, F-
dc.contributor.authorJin, YL-
dc.contributor.authorWoo, J-
dc.contributor.authorCheng, KK-
dc.contributor.authorLam, TH-
dc.contributor.authorXu, L-
dc.date.accessioned2020-11-23T08:19:52Z-
dc.date.available2020-11-23T08:19:52Z-
dc.date.issued2020-
dc.identifier.citationClinical Nutrition, 2020, v. 39 n. 11, p. 3442-3451-
dc.identifier.issn0261-5614-
dc.identifier.urihttp://hdl.handle.net/10722/293652-
dc.description.abstractBackground: Milk as a common diet is recommended by many guidelines, but the results on the association of milk consumption with the risk of cardiovascular disease (CVD) or cancer were contradictory. Moreover, evidence regarding milk consumption and mortality risk in Chinese is scarce. Objective: We examined the associations of milk consumption with the risk of all-cause, CVD and cancer mortality in a low milk consumption population using data from the Guangzhou Biobank Cohort Study. Design: 18,214 participants aged 50+ years without CVD history at baseline (2003–6) were included. Causes of death were identified through record linkage. Cox proportional hazards regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). Results: Of the 18,214 participants, 12,670 (69.6%) did not consume milk, 2669 (14.7%) had moderate (1–3 portions/week; 1 portion = 250 ml) and 2875 (15.8%) had high (3+ portions/week) consumption. During an average follow-up of 11.5 (standard deviation = 2.3) years, 2697 deaths occurred, including 917 CVD and 1029 cancer deaths. Compared with no consumption, the adjusted HR (95% CIs) of all-cause, CVD, ischemic heart disease (IHD) and stroke mortality for moderate milk consumption was 0.92 (0.81–1.04), 0.72 (0.57–0.92), 0.57 (0.38–0.85) and 0.77 (0.63–0.94), respectively. High consumption was associated with a higher risk of total cancer and esophagus cancer mortality, with the adjusted HR (95% CIs) being 1.33 (1.12–1.57) and 3.20 (1.21–8.43) respectively. No significant association of high consumption with lung cancer, liver cancer, gastrointestinal cancer, or colorectal and anal cancer was found. Conclusions: In our sample of Chinese with much lower milk consumption than those in the West, compared with no consumption, moderate milk consumption showed a lower risk of CVD mortality, but high milk consumption showed a higher risk of total cancer mortality. Further studies are warranted to verify the differential effects of milk on CVD and cancer.-
dc.languageeng-
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/clnu-
dc.relation.ispartofClinical Nutrition-
dc.subjectMilk consumption-
dc.subjectCardiovascular disease-
dc.subjectCancer-
dc.subjectIschemic heart disease-
dc.subjectStroke-
dc.titleMilk consumption and risk of mortality from all-cause, cardiovascular disease and cancer in older people-
dc.typeArticle-
dc.identifier.emailJiang, CQ: cqjiang@hkucc.hku.hk-
dc.identifier.emailZhang, WS: zhangws9@hku.hk-
dc.identifier.emailCheng, KK: chengkk@hkucc.hku.hk-
dc.identifier.emailLam, TH: hrmrlth@hkucc.hku.hk-
dc.identifier.emailXu, L: linxu@hku.hk-
dc.identifier.authorityLam, TH=rp00326-
dc.identifier.authorityXu, L=rp02030-
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.clnu.2020.03.003-
dc.identifier.pmid32229169-
dc.identifier.scopuseid_2-s2.0-85082507694-
dc.identifier.hkuros318970-
dc.identifier.volume39-
dc.identifier.issue11-
dc.identifier.spage3442-
dc.identifier.epage3451-
dc.identifier.isiWOS:000583382200025-
dc.publisher.placeNetherlands-
dc.identifier.issnl0261-5614-

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats