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Article: Efficacy of surgical masks or cloth masks in the prevention of viral transmission: systematic review, meta‐analysis, and proposal for future trial

TitleEfficacy of surgical masks or cloth masks in the prevention of viral transmission: systematic review, meta‐analysis, and proposal for future trial
Authors
KeywordsCOVID-19
face masks
SARS-CoV-2
systematic review
trial proposal
Issue Date2021
PublisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1756-5391
Citation
Journal of Evidence-Based Medicine, 2021, v. 14 n. 2, p. 97-111 How to Cite?
AbstractObjective: Recommendations for widespread use of face mask, including suggested type, should reflect the current published evidence and concurrently be studied. This review evaluates the preclinical and clinical evidence on use of cloth and surgical face masks in SARS-CoV-2 transmission and proposes a trial to gather further evidence. Methods: PubMed, EMbase, and the Cochrane Library were searched. Studies of SARS-CoV-2 and face masks and randomized controlled trials (RCTs) of n ≥ 50 for other respiratory illnesses were included. Results: Fourteen studies were included in this study. One preclinical and 1 observational cohort clinical study found significant benefit of masks in limiting SARS-CoV-2 transmission. Eleven RCTs in a meta-analysis studying other respiratory illnesses found no significant benefit of masks (±hand hygiene) for influenza-like-illness symptoms nor laboratory confirmed viruses. One RCT found a significant benefit of surgical masks compared with cloth masks. Conclusion: There is limited available preclinical and clinical evidence for face mask benefit in SARS-CoV-2. RCT evidence for other respiratory viral illnesses shows no significant benefit of masks in limiting transmission but is of poor quality and not SARS-CoV-2 specific. There is an urgent need for evidence from randomized controlled trials to investigate the efficacy of surgical and cloth masks on transmission of SARS-CoV-2 and user reported outcomes such as comfort and compliance.
DescriptionBronze open access
Persistent Identifierhttp://hdl.handle.net/10722/297681
ISSN
2020 SCImago Journal Rankings: 0.885
ISI Accession Number ID

 

DC FieldValueLanguage
dc.contributor.authorNanda, A-
dc.contributor.authorHung, I-
dc.contributor.authorKwong, A-
dc.contributor.authorMan, VCM-
dc.contributor.authorRoy, P-
dc.contributor.authorDavies, L-
dc.contributor.authorDouek, M-
dc.date.accessioned2021-03-23T04:20:13Z-
dc.date.available2021-03-23T04:20:13Z-
dc.date.issued2021-
dc.identifier.citationJournal of Evidence-Based Medicine, 2021, v. 14 n. 2, p. 97-111-
dc.identifier.issn1756-5383-
dc.identifier.urihttp://hdl.handle.net/10722/297681-
dc.descriptionBronze open access-
dc.description.abstractObjective: Recommendations for widespread use of face mask, including suggested type, should reflect the current published evidence and concurrently be studied. This review evaluates the preclinical and clinical evidence on use of cloth and surgical face masks in SARS-CoV-2 transmission and proposes a trial to gather further evidence. Methods: PubMed, EMbase, and the Cochrane Library were searched. Studies of SARS-CoV-2 and face masks and randomized controlled trials (RCTs) of n ≥ 50 for other respiratory illnesses were included. Results: Fourteen studies were included in this study. One preclinical and 1 observational cohort clinical study found significant benefit of masks in limiting SARS-CoV-2 transmission. Eleven RCTs in a meta-analysis studying other respiratory illnesses found no significant benefit of masks (±hand hygiene) for influenza-like-illness symptoms nor laboratory confirmed viruses. One RCT found a significant benefit of surgical masks compared with cloth masks. Conclusion: There is limited available preclinical and clinical evidence for face mask benefit in SARS-CoV-2. RCT evidence for other respiratory viral illnesses shows no significant benefit of masks in limiting transmission but is of poor quality and not SARS-CoV-2 specific. There is an urgent need for evidence from randomized controlled trials to investigate the efficacy of surgical and cloth masks on transmission of SARS-CoV-2 and user reported outcomes such as comfort and compliance.-
dc.languageeng-
dc.publisherWiley-Blackwell Publishing Asia. The Journal's web site is located at http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1756-5391-
dc.relation.ispartofJournal of Evidence-Based Medicine-
dc.rightsSubmitted (preprint) Version This is the pre-peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article using the DOI]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Accepted (peer-reviewed) Version This is the peer reviewed version of the following article: [FULL CITE], which has been published in final form at [Link to final article using the DOI]. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.-
dc.subjectCOVID-19-
dc.subjectface masks-
dc.subjectSARS-CoV-2-
dc.subjectsystematic review-
dc.subjecttrial proposal-
dc.titleEfficacy of surgical masks or cloth masks in the prevention of viral transmission: systematic review, meta‐analysis, and proposal for future trial-
dc.typeArticle-
dc.identifier.emailHung, I: ivanhung@hkucc.hku.hk-
dc.identifier.emailKwong, A: avakwong@hku.hk-
dc.identifier.authorityHung, I=rp00508-
dc.identifier.authorityKwong, A=rp01734-
dc.description.naturelink_to_OA_fulltext-
dc.identifier.doi10.1111/jebm.12424-
dc.identifier.scopuseid_2-s2.0-85100756471-
dc.identifier.hkuros321763-
dc.identifier.volume14-
dc.identifier.issue2-
dc.identifier.spage97-
dc.identifier.epage111-
dc.identifier.isiWOS:000658532100004-
dc.publisher.placeAustralia-

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