Quercetin: total-scale literature landscape analysis of a valuable nutraceutical with numerous potential applications in the promotion of human and animal health - a review

Abstract

Numerous investigations on quercetin have revealed that it effectively treats and prevents different diseases, acting as an anti-inflammatory, anti-bacterial, anti-proliferative, anti-atherogenic, anticoagulative, antioxidant, antidiabetic agent, etc. This work aimed to analyze the present research literature on quercetin in the context of human and animal health. The Web of Science Core Collection electronic database was searched with (quercetin*) AND (health* OR illness* OR disease* OR medic* OR pharma* OR drug* OR therap*). The resulted 15685 papers were bibliometrically evaluated with the aid of VOSviewer software. Besides the United States, the quercetin papers received global contributions, particularly from Asian countries such as China, India, and South Korea. Examples of frequently mentioned chemicals/chemical classes were flavonoid, kaempferol, rutin, polyphenol, and catechin. Examples of frequently mentioned medical conditions were cancer, Alzheimer's disease, and atherosclerosis. There are numerous reported beneficial effects of quercetin on human and animal health, which warrants further research for corroboration, understanding mechanism of action, and practical application.