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Article: Restoration of chemosensitivity by bortezomib: Implications for refractory myeloma

TitleRestoration of chemosensitivity by bortezomib: Implications for refractory myeloma
Authors
Chim, CSHwang, YYPang, CShek, TW
Issue Date2009
PublisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/nrclinonc/index.html
Citation
Nature Reviews Clinical Oncology, 2009, v. 6 n. 4, p. 237-240 How to Cite?
DOI: http://dx.doi.org/10.1038/nrclinonc.2009.15
AbstractBackground. A 59-year-old woman presented to the emergency department with a left rib fracture and was diagnosed with IgA multiple myeloma. The patient underwent autologous bone-marrow transplantation, and 14 months later she developed obstructive jaundice. Investigations. Serum protein electrophoresis, contrast CT of thorax and abdomen, endoscopic retrograde cholangiopancreatography with endoscopic biopsy and pleural biopsy. Diagnosis. Extramedullary plasmacytomas at pancreatic head and pleura. Management. Salvage chemotherapy regimens including bortezomib plus steroid, alkylators plus steroid, bortezomib plus anthracycline and radiotherapy, and combined bortezomib, cyclophosphamide, melphalan and steroid therapy.
Persistent Identifierhttp://hdl.handle.net/10722/59167
ISSN
1759-4774
2021 Impact Factor: 65.011
2020 SCImago Journal Rankings: 12.214
ISI Accession Number ID
WOS:000265853700012
References
References in Scopus

 

DC FieldValueLanguage
dc.contributor.authorChim, CSen_HK
dc.contributor.authorHwang, YYen_HK
dc.contributor.authorPang, Cen_HK
dc.contributor.authorShek, TWen_HK
dc.date.accessioned2010-05-31T03:44:11Z-
dc.date.available2010-05-31T03:44:11Z-
dc.date.issued2009en_HK
dc.identifier.citationNature Reviews Clinical Oncology, 2009, v. 6 n. 4, p. 237-240en_HK
dc.identifier.issn1759-4774en_HK
dc.identifier.urihttp://hdl.handle.net/10722/59167-
dc.description.abstractBackground. A 59-year-old woman presented to the emergency department with a left rib fracture and was diagnosed with IgA multiple myeloma. The patient underwent autologous bone-marrow transplantation, and 14 months later she developed obstructive jaundice. Investigations. Serum protein electrophoresis, contrast CT of thorax and abdomen, endoscopic retrograde cholangiopancreatography with endoscopic biopsy and pleural biopsy. Diagnosis. Extramedullary plasmacytomas at pancreatic head and pleura. Management. Salvage chemotherapy regimens including bortezomib plus steroid, alkylators plus steroid, bortezomib plus anthracycline and radiotherapy, and combined bortezomib, cyclophosphamide, melphalan and steroid therapy.en_HK
dc.languageengen_HK
dc.publisherNature Publishing Group. The Journal's web site is located at http://www.nature.com/nrclinonc/index.htmlen_HK
dc.relation.ispartofNature Reviews Clinical Oncologyen_HK
dc.subject.meshAntineoplastic Agents - administration & dosageen_HK
dc.subject.meshBoronic Acids - administration & dosageen_HK
dc.subject.meshDose-Response Relationship, Drugen_HK
dc.subject.meshDrug Resistance, Neoplasmen_HK
dc.subject.meshFemaleen_HK
dc.subject.meshHumansen_HK
dc.subject.meshMiddle Ageden_HK
dc.subject.meshMultiple Myeloma - drug therapy - pathologyen_HK
dc.subject.meshPancreatic Neoplasms - drug therapyen_HK
dc.subject.meshPleural Neoplasms - drug therapyen_HK
dc.subject.meshProtease Inhibitors - administration & dosageen_HK
dc.subject.meshPyrazines - administration & dosageen_HK
dc.subject.meshTreatment Outcomeen_HK
dc.titleRestoration of chemosensitivity by bortezomib: Implications for refractory myelomaen_HK
dc.typeArticleen_HK
dc.identifier.emailChim, CS:jcschim@hku.hken_HK
dc.identifier.authorityChim, CS=rp00408en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1038/nrclinonc.2009.15en_HK
dc.identifier.pmid19333230en_HK
dc.identifier.scopuseid_2-s2.0-67650189466en_HK
dc.identifier.hkuros158560en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-67650189466&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume6en_HK
dc.identifier.issue4en_HK
dc.identifier.spage237en_HK
dc.identifier.epage240en_HK
dc.identifier.isiWOS:000265853700012-
dc.publisher.placeUnited Kingdomen_HK
dc.identifier.scopusauthoridChim, CS=7004597253en_HK
dc.identifier.scopusauthoridHwang, YY=26532944100en_HK
dc.identifier.scopusauthoridPang, C=25641666400en_HK
dc.identifier.scopusauthoridShek, TW=7005479861en_HK
dc.identifier.issnl1759-4774-

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