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- Publisher Website: 10.1177/0310057X9602400104
- Scopus: eid_2-s2.0-0030057644
- PMID: 8669648
- WOS: WOS:A1996TW75000004
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Article: The development of hypercoagulability state, as measured by thrombelastography, associated with intraoperative surgical blood loss
Title | The development of hypercoagulability state, as measured by thrombelastography, associated with intraoperative surgical blood loss |
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Authors | |
Keywords | Blood loss, hypercoagulability Thrombelastography |
Issue Date | 1996 |
Publisher | Australian Society of Anaesthetists. The Journal's web site is located at http://www.aaic.net.au |
Citation | Anaesthesia And Intensive Care, 1996, v. 24 n. 1, p. 20-25 How to Cite? |
Abstract | Thrombelastographic evidence of hypercoagulability, including shortening of r-time (P<0.01); shortening of k-time (P<0.01); and widening of trace angle (P<0.01) were observed in a group of 21 Chinese surgical patients when (a) the amount of blood loss was at an estimated 10% of total blood volume and (b) the amount of blood loss was at an estimated 15% of blood volume. The amount of blood loss was documented by haemoglobin measurements. No evidence of hypercoagulability,vas observed at around one hour into the operation in the absence of bleeding. We conclude that a mild to moderate degree of surgical blood loss with haemodilution is associated with the development of hypercoagulability as measured by thrombelastography. Further studies looking at the thrombebolic outcome in such groups of patients is warranted. It is also suggested that caution should be exercised in the use of intraoperative isovolaemic haemoldilution until the phenomenon is further investigated. |
Persistent Identifier | http://hdl.handle.net/10722/67305 |
ISSN | 2021 Impact Factor: 1.512 2020 SCImago Journal Rankings: 0.494 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ng, KFJ | en_HK |
dc.contributor.author | Lo, JWR | en_HK |
dc.date.accessioned | 2010-09-06T05:53:48Z | - |
dc.date.available | 2010-09-06T05:53:48Z | - |
dc.date.issued | 1996 | en_HK |
dc.identifier.citation | Anaesthesia And Intensive Care, 1996, v. 24 n. 1, p. 20-25 | en_HK |
dc.identifier.issn | 0310-057X | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/67305 | - |
dc.description.abstract | Thrombelastographic evidence of hypercoagulability, including shortening of r-time (P<0.01); shortening of k-time (P<0.01); and widening of trace angle (P<0.01) were observed in a group of 21 Chinese surgical patients when (a) the amount of blood loss was at an estimated 10% of total blood volume and (b) the amount of blood loss was at an estimated 15% of blood volume. The amount of blood loss was documented by haemoglobin measurements. No evidence of hypercoagulability,vas observed at around one hour into the operation in the absence of bleeding. We conclude that a mild to moderate degree of surgical blood loss with haemodilution is associated with the development of hypercoagulability as measured by thrombelastography. Further studies looking at the thrombebolic outcome in such groups of patients is warranted. It is also suggested that caution should be exercised in the use of intraoperative isovolaemic haemoldilution until the phenomenon is further investigated. | en_HK |
dc.language | eng | en_HK |
dc.publisher | Australian Society of Anaesthetists. The Journal's web site is located at http://www.aaic.net.au | en_HK |
dc.relation.ispartof | Anaesthesia and Intensive Care | en_HK |
dc.subject | Blood loss, hypercoagulability | - |
dc.subject | Thrombelastography | - |
dc.subject.mesh | Adult | en_HK |
dc.subject.mesh | Aged | en_HK |
dc.subject.mesh | Blood Coagulation Disorders - diagnosis - etiology | en_HK |
dc.subject.mesh | Blood Loss, Surgical | en_HK |
dc.subject.mesh | Female | en_HK |
dc.subject.mesh | Hemodilution - adverse effects | en_HK |
dc.subject.mesh | Humans | en_HK |
dc.subject.mesh | Intraoperative Period | en_HK |
dc.subject.mesh | Male | en_HK |
dc.subject.mesh | Middle Aged | en_HK |
dc.subject.mesh | Thrombelastography - methods | en_HK |
dc.title | The development of hypercoagulability state, as measured by thrombelastography, associated with intraoperative surgical blood loss | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0310-057X&volume=24&spage=20&epage=25&date=1996&atitle=The+development+of+hypercoagulability+state,+as+measured+by+thrombelastography,+associated+with+intraoperative+surgical+blood+loss | en_HK |
dc.identifier.email | Ng, KFJ:jkfng@hkucc.hku.hk | en_HK |
dc.identifier.authority | Ng, KFJ=rp00544 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1177/0310057X9602400104 | - |
dc.identifier.pmid | 8669648 | - |
dc.identifier.scopus | eid_2-s2.0-0030057644 | en_HK |
dc.identifier.hkuros | 15301 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-0030057644&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 24 | en_HK |
dc.identifier.issue | 1 | en_HK |
dc.identifier.spage | 20 | en_HK |
dc.identifier.epage | 25 | en_HK |
dc.identifier.isi | WOS:A1996TW75000004 | - |
dc.publisher.place | Australia | en_HK |
dc.identifier.issnl | 0310-057X | - |