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Showing results 1 to 18 of 18

	Title	Author(s)	Issue Date	Views
	A global scientific strategy to cure hepatitis B Journal:The Lancet Gastroenterology & Hepatology	Revill, PA Chisari, FV Block, JM Dandr, M Gehring, AJ Guo, H Hu, J Kramvis, A Lampertico, P Janssen, HLA Levrero, M Li, W Liang, TJ Lim, SG Lu, F Penicaud, MC Tavis, JE Thimme, R Arbuthnot, P Boonstra, A Chang, KM Chen, PJ Glebe, D Guidotti, LG Fellay, J Ferrari, C Jansen, L Lau, DTY Lok, AS Maini, MK Mason, W Matthews, G Paraskevis, D Peterse, J Rehermann, B Shin, EC Thompson, A van Bömmel, F Wang, FS Watashi, K Yang, HC Yuan, Z Yuen, MF Block, T Miller, V Protzer, U Bréchot, C Locarnini, S Peters, MG Schinazi, RF Zoulim, F	2019	60
	A phase 1 study to evaluate safety and tolerability of escalating single doses of the hepatitis B virus RNA interference drug ARC-521 in a healthy volunteer population Proceeding/Conference:Journal of Hepatology	Gane, E Schwabe, C Given, B Schluep, T Hamilton, J Lai, CL Locarnini, S Lau, J Ferrari, C Gish, R	2017	65
	Differential reductions in viral antigens expressed from cccDNAVS integrated DNA in treatment naïve HBeAg positive and negative patients with chronic HBV after RNA interference therapy with ARC-520 Proceeding/Conference:Journal of Hepatology	Yuen, RMF Chan, HLY Liu, K Given, BD Schluep, T Hamilton, J Lai, CL Locarnini, SA Lau, JYN Ferrari, C Gish, RG	2016	88
	Dose response with the RNA interference (RNAi) therapy JNJ-3989 combined with nucleos(t)ide analogue (NA) treatment in expanded cohorts of patients (pts) with chronic hepatitis B (CHB) Proceeding/Conference:Hepatology	Gane, EJ Locarnini, S Lim, TH Strasser, SI Sievert, W Cheng, W Thompson, A Given, BD Schluep, T Hamilton, J Biermer, M Kalmeijer, R Beumont-Mauviel, M Lenz, O Cloherty, G Wong, DKH Schwabe, C Jackson, K Ferrari, C Lai, CL Gish, RG Yuen, RMF	2019	41
	Effective inhibition of cccDNA derived mRNA/viral antigens and tolerability with ARC-520 Proceeding/Conference:Hepatology International	Yuen, RMF Chan, HLY Liu, SHK Given, BD Schluep, T Hamilton, J Lai, CL Locarnini, SA Lau, JYN Ferrari, C Gish, RG	2016	61
	First clinical experience with RNA interference [RNAI]-based triple combination therapy in chronic hepatitis B (CHB): JNJ-73763989 (JNJ-3989), JNJ-56136379 (JNJ-6379) and a nucleos(t)ide analogue (NA) Proceeding/Conference:Hepatology	Yuen, RMF Locarnini, S Given, B Schluep, T Hamilton, J Biermer, M Kalmeijer, R Beumont-Mauviel, M Lenz, O Cloherty, G Jackson, K Ferrari, C Lai, CL Liu, SHK Mak, LY Wong, DKH To, WP Ko, KL Gish, RG	2019	112
	First results with RNA interference (RNAi) in chronic hepatitis b (CHB) using ARO-HBV Proceeding/Conference:Hepatology	Gane, EJ Locarnini, S Lim, TH Strasser, S Sievert, W Cheng, W Thompson, A Given, B Schluep, T Hamilton, J Li, Z Cloherty, G Wong, DKH Schwabe, C Jackson, K Ferrari, C Lai, CL Gish, RG Yuen, RMF	2018	83
	Long-term serological, virological and histological responses to RNA inhibition by ARC-520 in Chinese chronic hepatitis B patients on entecavir treatment Journal:Gut	Yuen, MF Wong, DKH Schluep, T Lai, CL Ferrari, C Locarnini, S Lo, RCL Gish, R Hamilton, J Wooddell, CI Mak, LY Given, BD	2021	16
	Predicting HBsAg clearance responses during ARC-520 RNA interference (RNAi) therapy based on HBsAg epitope profile analysis Proceeding/Conference:Journal of Hepatology	Walsh, R Yuen, L Hammond, R Deerain, J Given, B Schluep, T Yuen, MF Chan, HLY Lai, CL Hamilton, J Lau, JY Ferrari, C Gish, RG Locarnini, SA	2016	69
	Prolonged RNA interference therapy with ARC-520 Injection in treatment naïve, HBeAg positive and negative patients with chronic HBV results in significant reductions of HBs antigen Proceeding/Conference:Journal of Hepatology	Yuen, RMF Liu, SHK Chan, HLY Given, BD Schluep, T Hamilton, J Lai, CL Locarnini, SA Lau, JY Ferrari, C Gish, RG	2017	63
	RNA interference therapy with ARC-520 Injection results in long term off-therapy antigen reductions in treatment naïve, HBeAg positive and negative patients with chronic HBV Proceeding/Conference:Journal of Hepatology	Yuen, RMF Liu, SHK Given, B Schluep, T Hamilton, J Lai, CL Locarnini, S Jackson, K Lai, JY Ferrari, C Gish, RG.	2018	88
	RNA Interference Therapy With ARC‐520 Results in Prolonged Hepatitis B Surface Antigen Response in Patients With Chronic Hepatitis B Infection Journal:Hepatology	Yuen, MF Schiefke, I Yoon, JH Ahn, SH Heo, J Kim, JH Chan, HLY Yoon, KT Klinker, H Manns, M Petersen, J Schluep, T Hamilton, J Given, BD Ferrari, C Lai, CL Locarnini, SA Gish, RG	2020	20
	RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg Journal:Science Translational Medicine	Wooddell, CI Yuen, RMF Chan, HLY Gish, RG Locarnini, SA Chavez, D Ferrari, C Given, BD Hamilton, J Kanner, SB Lai, CL Lai, JYN Schluep, T Xu, Z Lanford, RE Lewis, DL	2017	32
	Short interfering RNA JNJ-3989 combination therapy in chronic hepatitis B shows potent reduction of all viral markers but no correlate was identified for HBsAg reduction and baseline factors Proceeding/Conference:Journal of Hepatology	Gane, E Locarnini, S Lim, TH Strasser, S Sievert, W Cheng, W Thompson, A Given, B Schluep, T Hamilton, J Biermer, M Kalmeijer, R Beumont-Mauviel, M Lenz, O De Ridder, F Cloherty, G Wong, DKH Schwabe, C Jackson, K Ferrari, C Lai, CL Gish, RG Yuen, RMF	2021	44
	Short interfering RNA JNJ-3989 combination therapy in chronic hepatitis B (CHB) shows potent reduction of all viral markers but no correlate was identified for HBsAg reduction and baseline factors Proceeding/Conference:APASL 2022, Seoul, Korea, 30 Mar - 3 Apr 2022. Hepatology International	Gane, E Locarnini, S Lim, TH Strasser, SI Sievert, W Cheng, W Thompson, AJ Given, BD Schluep, T Hamilton, J Biermer, M Kalmeijer, R Beumont, M Lenz, O Ridder, FD Cloherty, G Wong, DKH Schwabe, C Jackson, K Ferrari, C Lai, CL Gish, R Yuen, RMF	2022
	Short term RNA interference therapy in chronic hepatitis B using JNJ-3989 brings majority of patients to HBsAg < 100 IU/ml threshold Proceeding/Conference:Journal of Hepatology	Yuen, RMF Locarnini, S Lim, TH Strasser, S Sievert, W Cheng, W Thompson, A Given, B Schluep, T Hamilton, J Cloherty, G Wong, DKH Schwabe, C Jackson, K Ferrari, C Lai, CL Gish, RG Gane, E	2019	73
	Short-term treatment with RNA interference therapy, JNJ-3989, results in sustained hepatitis B surface antigen suppression in patients with chronic hepatitis B receiving nucleos(t)ide analogue treatment Proceeding/Conference:Journal of Hepatology	Gane, E Locarnini, S Lim, TH Strasser, S Sievert, W Cheng, W Thompson, A Given, B Schluep, T Hamilton, J Biermer, M Kalmeijer, R Beumont-Mauviel, M Lenz, O Cloherty, G Wong, DKH Schwabe, C Jackson, K Ferrari, C Lai, CL Gish, RG Yuen, RMF	2020	78
	Update of the statements on biology and clinical impact of occult hepatitis B virus infection Journal:Journal of Hepatology	Raimondo, G Locarnini, S Pollicino, T Levrero, M Zoulim, F Lok, AS Allain, JP Berg, T Bertoletti, A Brunetto, MR Bruno, R Chen, DS Coppola, N Cornberg, M Craxì, A Dandri, M Di Marco, V Ferrari, C Gaeta, GB Glebe, D Guidotti, LG Kramvis, A Lampertico, P Li, C Liang, J Marzano, A Michalak, TI Pawlotsky, JM Prati, D Puoti, M Samuel, D Soriano, V Squadrito, G Sureau, C Trepo, C Yuen, MF	2019	51

Showing results 1 to 18 of 18