Collection View Count

Geo Map
Region#
AS - Asia45904
NA - North America39036
EU - Europe25233
AF - Africa6108
OC - Oceania2882
HKU - The University of Hong Kong546
SA - South America68
UND - Undefined1239
Total121016
Country#
US - United States38731
CN - China21123
GB - United Kingdom10785
SG - Singapore8181
IE - Ireland6870
KR - Republic of Korea6469
JP - Japan5436
ZA - South Africa5333
HK - Hong Kong3831
NL - Netherlands3565
OTH - Others10692
Total121016
City#
Ashburn16691
Singapore8113
Dublin6869
Beijing6650
Johannesburg5330
Tokyo4229
Fairfield3292
Sydney2789
Amsterdam2647
Des Moines2231
Others62175
Total121016
SAPI: A direct-methods program for finding heavy-atom sites with SAD or SIR data188
Alpha and beta receptors in the bronchial artery37
Differential induction of adrenomedullin, interleukins and tumour necrosis factor-α by lipopolysaccharide in rat tissues in vivo135
The influence of extracellular pH, sodium propionate and trimethylamine on excitation-contraction coupling in the rat tail artery100
Effect of reserpine on catecholamine contents and met-enkephalin and β-endorphin levels in the hypothalamus and the pituitary51
The cerebellar-hypothalamic circuits: Potential pathways underlying cerebellar involvement in somatic-visceral integration94
GDP-ribosyl cyclase activity as a measure of CD38 induction by retinoic acid in HL-60 cells177
Ear piercing: A review on the legislative regulations and potential health hazards; its relevance to family physicians195
Structures and activities of cyclic ADP-ribose, NAADP and their metabolic enzymes120
Lycium barbarum polysaccharides protect rat liver from non-alcoholic steatohepatitis-induced injury75
Comment on "the Arabiclopsis circadian clock incorporates a cADPR-based feedback loop"194
Appearance of adenosine in venous blood from the contracting gracilis muscle and its role in vasodilatation in the dog73
Down regulation of 2 125I iodomelatonin binding sites in the guinea pig spleen by melatonin but not by naltrexone treatment114
Derivation of clinically applicable schwann cells from bone marrow stromal cells for neural repair and regeneration153
Variations of mt1 melatonin receptor density in the rat uterus during decidualization, the estrous cycle and in response to exogenous steroid treatment51
Melatonin and melatonin receptors : Recent advances95
DNA-loaded chitosan oligosaccharide nanoparticles with enhanced permeability across Calu-3 cells139
LSCALE - The new normalization, scaling and absorption correction program in the Daresbury Laue software suite189
Structural basis of activation-dependent binding of ligand-mimetic antibody AL-57 to integrin LFA-1173
Differential localization of metabotropic glutamae receptors 1 and 2/3 in the rat striatum during early postnatal development81
Induced pluripotent stem cells as a disease model for studying inherited arrhythmias: promises and hurdles77
Dopaminergic and substantia nigral regulation of hippocampal epilepsy in kainic acid treated rats108
Changes in intracellular acidic compartments in sea urchin eggs after activation57
Use of preputial skin for the release of burn contractures in children126
Structural Insights into the Regulatory Mechanism of the Response Regulator RocR from Pseudomonas aeruginosa in Cyclic Di-GMP Signaling52
High throughput fluorescence-based assays for cyclic ADP-ribose, NAADP, and their metabolic enzymes151
An Improved Enzymatic Cycling Assay for NAADP83
Inhibitors of inducible nitric oxide (NO) synthase are more effective than an NO donor in reducing carbon-tetrachloride induced acute liver injury120
Rapid regulation of adrenomedullin in metabolically compromised vascular smooth muscle cells158
Protective effect of melatonin against hippocampal injury of rats with intermittent hypoxia189
Control of the mode of excitation-contraction coupling by Ca2+ stores in bovine trachealis muscle41
Specific binding of cyclic ADP-ribose to calcium-storing microsomes from sea urchin eggs46
Direct methods in superspace. I. Preliminary theory and test on the determination of incommensurate modulated structures194
Multiplicity of Ca2+ messengers and Ca2+ stores: A perspective from cyclic ADP-ribose and NAADP43
Acetylcholine Ca2+ stores refilling directly involves a dihydropyridine-sensitive channel in dog trachea52
Putative melatonin receptors in the male reproductive tissues176
Reversal of long-latency reflexes in first dorsal interosseous during a force-tracking task45
Medullary loci critical for expression of gasping in adult rats58
SKF-96365 strongly inhibits voltage-gated sodium current in rat ventricular myocytes45
Pathogenic roles of the carotid body inflammation in sleep apnea42
Jaw-opening reflex as pain response in rabbit: preliminary report.55
Intracerebroventricular atrial natriuretic factor (ANF) antiserum inhibits volume-induced ANF in sheep: Evidence for the brain's regulation of ANF secretion87
Intrathecal morphine preconditioning induces cardioprotection via activation of delta, kappa, and mu opioid receptors in rats112
Treatment with the 3-Ketoacyl-CoA Thiolase Inhibitor Trimetazidine Does Not Exacerbate Whole-Body Insulin Resistance in Obese Mice75
Functional expression of soluble forms of human CD38 in Escherichia coli and Pichia pastoris190
Regulation of human cardiac KCNQ1/KCNE1 channel by epidermal growth factor receptor kinase130
Increased adrenomedullin expression in the lung and the spleen by endotoxin76
Multiple calcium stores: separate but interacting.41
Relationship between muscarinic receptor reserve and mode of excitation-contraction coupling in airway smooth muscle23
Cyclic nucleotide-dependent protein kinase (PK) activity in the hypoxic isolated perfused rat heart87
Cobra cardiotoxin induced initial transient relaxation followed by contraction in rat aortic rings44
Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD3849
Molecular interaction of flagellar export chaperone FliS and cochaperone HP1076 in Helicobacter pylori173
Calcium homeostasis modulator 1 (CALHM1) is the pore-forming subunit of an ion channel that mediates extracellular Ca2+ regulation of neuronal excitability74
Therapeutic approaches to non-alcoholic fatty liver disease: past achievements and future chanllenges97
Anoxia-induced depolarization in CA1 hippocampal neurons: Role of Na+- dependent mechanisms173
Gs and Gi coupling of adrenomedullin in adult rat ventricular myocytes156
Vestibular afferent innervation in the vestibular efferent nucleus of rats115
Choleretic effects of acetophenone derivatives and analogues on rats36
β-Adrenoceptor activates endothelium-dependent release of nitric oxide in rat aorta35
Cyclic ADP-ribose links metabolism to multiple fission in the dinoflagellate Crypthecodinium cohnii203
Asymmetric labeling of amino lipids in liposomes56
LAUEGEN version 6.0 and INTLDM223
Structure solution of azurin II from Alcaligenes xylosoxidans using the Laue method: Possibility of studying in situ redox changes using X-rays175
Pharmacological characterization, molecular subtyping, and autoradiographic localization of putative melatonin receptors in uterine endometrium of estrous rats184
Elevation of arterial potassium during acute systemic hypoxia is abolished by alkalosis190
A membrane potential-sensitive Na+-H+ exchange system in flagella isolated from sea urchin spermatozoa36
Proteomic signatures of epidermal growth factor receptor and survival signal pathways correspond to gefitinib sensitivity in head and neck cancer47
An investigation of the vascular organisation of the canine submandibular gland39
Nasal venous drainage in the dog30
Chronic intermittent hypoxia induces local inflammation of the rat carotid body via functional upregulation of proinflammatory cytokine pathways177
Insulin-mediated upregulation of KCa3.1 channels promotes cell migration and proliferation in rat vascular smooth muscle194
Use of single isomorphous replacement data of proteins - Resolving the phase ambiguity and a new procedure for phase extension177
Cytosolic CD38 protein forms intact disulfides and is active in elevating intracellular cyclic ADP-ribose169
The Laue Data Module (LDM) - a software development for Laue X-ray diffraction data processing196
Telomerase activity is not related to apoptosis in leukemic cell lines211
Identification of ADP-ribosylation sites of CD38 mutants by precursor ion scanning mass spectrometry49
A volatile inhibitor immobilizes sea urchin sperm in semen by depressing the intracellular pH58
Properties of otolith-related vestibular nuclear neurons in neonatal rats105
Thio-NADP Is Not an Antagonist of NAADP42
OASIS: A computer program for breaking phase ambiguity in one-wavelength anomalous scattering or single isomorphous substitution (replacement) data225
Cdk5 regulates EphA4-mediated dendritic spine retraction through an ephexin1-dependent mechanism85
Endothelin-1-mediated coronary vasoconstriction deteriorates myocardial depression in hearts isolated from lipopolysaccharide-treated rats: Interaction with nitric oxide167
Adrenomedullin Increases the Short-Circuit Current in the Mouse Seminal Vesicle: Actions on Chloride Secretion65
Crossed sacculo ocular pathway via the Deiters' nucleus in cats66
Downregulation of glial glutamate transporters after dopamine denervation in the striatum of 6-hydroxydopamine-lesioned rats67
Significant up-regulation of nestin protein in the neostriatum of MPTP-treated mice: Are the striatal astrocytes regionally activated after systemic MPTP administration?131
NAADP: An emerging calcium signaling molecule60
Developmental distribution of vestibular nuclear neurons responsive to different speeds of horizontal translation181
Crystallographic data collection using a 0.22% bandwidth multilayer172
Adenosine triphosphate utilization rates and metabolic pool sizes in intact cells measured by transfer of 18O from water135
Neural Stem Cells Harvested from Live Brains by Antibody-Conjugated Magnetic Nanoparticles71
Potential application of induced pluripotent stem cells in cell replacement therapy for parkinson's disease137
Frequency tuning and firing pattern properties of auditory thalamic neurons: An in vivo intracellular recording from the guinea pig164
Cyclic ADP-ribose: A new member of a super family of signalling cyclic nucleotides60
The Social Costs in Communication Hiccups Between Native and Nonnative Speakers186
Renin-angiotensin system in the carotid body165
Paracrine-autocrine mechanisms in the carotid body function at high altitude and in disease29
The calmodulin inhibitor N-(6-aminohexyl)-5-chloro-1-naphthalene sulphonamide directly blocks human ether à-go-go-related gene potassium channels stably expressed in human embryonic kidney 293 cells140
Maturation of canal-related brainstem neurons in the detection of horizontal angular acceleration in rats228
Lithium attenuates the effects of dynorphin A(1-13) on inositol 1,4,5-trisphosphate and intracellular Ca2+ in rat ventricular myocytes164
Combining direct methods with isomorphous replacement or anomalous scattering data. VIII. Phasing experimental SIR data with the replacing atoms in a centrosymmetric arrangement249
囊性纖維化跨膜轉運調節體氯離子通道——跨上皮離子轉運的多功能引擎91
M 1and M 3 muscarinic receptors mediate relaxation and contraction in canine nasal veins147
Pinealectomy affects the diurnal varitations in 2[125I]iodomelatonin binding sites in chicken.104
A study of H+ transport in gastric microsomal vesicles using fluorescent probes67
Localization of the cyclic ADP-ribose-dependent calcium signaling pathway in hepatocyte nucleus48
Purification, characterization, crystallization and preliminary X-ray crystallographic analysis of two novel C-type lectin-like proteins: Aall-A and Aall-B from Deinagkistrodon acutus venom177
Protein expression and purification of integrin I domains and IgSF ligands for crystallography163
Cardiovascular effects of microinjection of sodium glutamate into the rostral and caudal ventrolateral medulla in spontaneously hypertensive rats104
Local hypoxia does not elevate adenosine output from isolated gracilis muscle in anaesthetized dogs19
Analysis of 5-methoxytryptamine at the femtomole level in the rat and quail brain by gas chromatography-electron-capture negative-ion chemical ionization mass spectrometry104
Selectively inhibition of oxalate-stimulated Ca2+ transport by cyclopiazonic acid and thapsigargin in smooth muscle microsomes125
ADP-ribosyl cyclase: an enzyme that cyclizes NAD+ into a calcium-mobilizing metabolite71
Relationship of rostral ventrolateral medullary neurons and angiotensin in the central control of blood pressure171
CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5′-Diphosphate Ribose Template55
Requirement of Ras/MAPK pathway activation by transforming growth factor β for transforming growth factor β1 production in a Smad-dependent pathway56
Differential effects of central ghrelin on fatty acid metabolism in hypothalamic ventral medial and arcuate nuclei60
The presenilin-2 loop peptide perturbs intracellular Ca2+ homeostasis and accelerates apoptosis189
Effect of uvulonodular lesion on spontaneous discharge activities in the vestibular nucleus of rats32
Nitric oxide-induced mobilization of intracellular calcium via the cyclic ADP-ribose signaling pathway46
NAADP: a universal Ca2+ trigger.181
Melatonin and prostate cancer cell proliferation: Interplay with castration, epidermal growth factor, and androgen sensitivity167
Inhibition of carnitine palmitoyltransferase-1 activity alleviates insulin resistance in diet-induced obese mice55
Effects of opiates on the spinal trigeminal and cuneate nuclei of cats32
Transforming growth factor β signaling through Smad1 in human breast cancer cells45
Forskolin fails to activate L-type calcium current in hypertrophied cardiomyocytes of chronically hypoxic rats203
Structural basis of FliG-FliM interaction in Helicobacter pylori.27
Response characteristics of cerebellar dentate and lateral cortex neurons to sinusoidal stimulation of neck and labyrinth receptors49
Interstitial adenosine concentration in rat red or white skeletal muscle during systemic hypoxia or contractions177
Spontaneous activity of otolith neurons in the vestibular nucleus of rats after inferior olive lesion34
Modulation of blood glucose by melatonin: A direct action on melatonin receptors in mouse hepatocytes51
The effect of age on the response of the rat brains to continuous β-amyloid infusion52
Inhibition of androgen-sensitive LNCaP prostate cancer growth in vivo by melatonin: Association of antiproliferative action of the pineal hormone with mt1 receptor protein expression56
Studies on CD38 Inhibitors and Their Application to cADPR-Mediated Ca2+ Signaling38
Crystallographic phasing with NMR models: an envelope approach52
Calcium signaling by cyclic ADP-ribose, NAADP, and inositol trisphosphate are involved in distinct functions in Ascidian oocytes40
Expression of Eph receptors in skeletal muscle and their localization at the neuromuscular junction70
Towards rational and evidence-based use of melatonin in prostate cancer prevention and treatment163
Structure and promoter characterization of aldo-keto reductase family 1 B10 gene181
Increased prospective memory interference in normal and pathological aging: different roles of motor and verbal processing speed185
Corticofugal modulation of acoustically induced Fos expression in the rat auditory pathway193
Structural basis for discriminatory recognition of Plasmodium lactate dehydrogenase by a DNA aptamer82
Bone marrow-derived Schwann cells achieve fate commitment - a prerequisite for remyelination therapy216
Stimulus-specific adaptation at the synapse level in vitro61
Toward maturation of the vestibular system: Neural circuits and neuronal properties134
Breast reconstruction with transverse rectus abdominis musculocutaneous (TRAM) flap in young women with breast cancer130
Effects of H1 antihistamines on canine nasal vascular and airway resistances44
Erratum: "Modulatory effect of cortical activation on the lemniscal auditory thalamus of the guinea pig" (Journal of Neurophysiology (August 2002) 88 (1040-1050))39
Venous adenosine content and vascular responses in dog hind-limb skeletal muscles during twitch contraction.59
Regulation of nuclear Ca2+ signaling by translocation of the Ca2+ messenger synthesizing enzyme ADP-ribosyl cyclase during neuronal depolarization176
Expression of vesicular glutamate transporters in peripheral vestibular structures and vestibular nuclear complex of rat219
Radioimmunoassay for measuring endogenous levels of cyclic ADP-Ribose in tissues154
Constant light exposure increases 2-[125I]iodomelatonin binding sites in the guinea pig spleen64
Effects of lung inflation on nasal airway resistance in the anesthetized rat56
A novel fluorescent cell membrane-permeable caged cyclic ADP-ribose analogue97
Expression, purification, crystallization and preliminary X-ray analysis of full-length human RIG-I.62
Melatonin ameliorates calcium homeostasis in myocardial and ischemia-reperfusion injury in chronically hypoxic rats123
Structural basis for RNA binding and homo-oligomer formation by influenza B virus nucleoprotein208
Tetrandrine, a calcium antagonist of Chinese herbal origin, interacts with vascular muscle α1-adrenoceptor50
BKCa and hEag1 channels regulate cell proliferation and differentiation in human bone marrow-derived mesenchymal stem cells.54
Molecular and cellular analyses of melatonin receptor-mediated cAMP signaling in rat corpus epididymis161
Increase or decrease in nasal airway resistance induced by acetylcholine in anesthetized dogs: Vascular mechanisms47
Increased endogenous nitric oxide release by iron chelation and purinergic activation in the rat carotid body98
Changes of internal pH associated with initiation of motility and acrosome reaction of sea urchin sperm58
Purification, partial characterization, crystallization and preliminary X-ray diffraction of two cysteine-rich secretory proteins from Naja atra and Trimeresurus stejnegeri venoms191
Incidence and cluster occurrence of palatal fistula after furlow palatoplasty by a single surgeon196
Cardiac effects of the extract and active components of radix stephaniae tetrandrae: I. Electrically-induced intracellular calcium transient and protein release during the calcium paradox145
Characterization and application of photogeneration of calcium mobilizers cADP-ribose and nicotinic acid adenine dinucleotide phosphate from caged analogs45
Effects of alcohols on gastric and small intestinal apical membrane integrity and fluidity55
The influence of blood flow rate on adenosine release from contracting dog skeletal muscle58
Caged cyclic ADP-ribose. Synthesis and use36
Expression of Trk receptors in otolith-related neurons in the vestibular nucleus of rats195
Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption79
Deacylation Mechanism by SIRT2 Revealed in the 1′-SH-2′-O-Myristoyl Intermediate Structure218
Magnesium ions but not ATP inhibit cyclic ADP-ribose-induced calcium release158
Effect of guanosine 5'-0-(3-thiotriphosphate) (GTPyS) on the high affinity 2 125I iodomelatonin binding sites in the guinea pig spleen: evidence for a direct action of melatonin on the immune system94
Effects of cortical stimulation on auditory-responsive thalamic neurones in anaesthetized guinea pigs177
Influence of interleukin-2 on Ca2+ handling in rat ventricular myocytes131
Potential involvement of mt1 receptor and attenuated sex steroid-induced calcium influx in the direct anti-proliferative action of melatonin on androgen-responsive LNCaP human prostate cancer cells147
Identification of cyclic ADP-ribose-binding proteins by photoaffinity labeling41
Large-scale production of human CD38 in yeast by fermentation46
Unraveling regulatory programs for NF-kappaB, p53 and microRNAs in head and neck squamous cell carcinoma62
Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs37
Inhibition of [3H]-U69593 binding and the cardiac effects of U50,488H by calcium channel blockers in the rat heart187
Transgenic mice overexpressing aldose reductase in Schwann cells show more severe nerve conduction velocity deficit and oxidative stress under hyperglycemic stress184
Ion channels in mesenchymal stem cells from rat bone marrow167
Adrenomedullin and its receptor components in adipose tissues: Differences between white and brown fats and the effects of adrenergic stimulation54
Cholinergic neurons expressing substance P receptor (NK1) in the basal forebrain of the rat: A double immunocytochemical study90
Recent advances in understanding the roles of Cdk5 in synaptic plasticity69
Identification of brain-derived neurotrophic factor in nestin-expressing astroglial cells in the neostriatum of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-treated mice48
Regulation of cyclic GMP metabolism in toad photoreceptors. Definition of the metabolic events subserving photoexcited and attenuated states131
Direct-method structure determination of the native Azurin II protein using one-wavelength anomalous scattering data123
Isolating nuclei from cultured cells for patch-clamp electrophysiology of intracellular Ca(2+) channels52
Neuronal response sensitivity to bidirectional off-vertical axis rotations: A dimension of imbalance in the bilateral vestibular nuclei of cats after unilateral labyrinthectomy194
Up-regulation in expression of vesicular glutamate transporter 3 in substantia nigra but not in striatum of 6-hydroxydopamine-lesioned rats72
Novel role of the Ca2+-ATPase in NMDA-induced intracellular acidification83
Cortisol decreases 2[125I]iodomelatonin binding sites in the duck thymus183
High resolution pair-distance distribution function P (r) of protein solutions208
Solution of protein crystallographic structures by high-pressure cryocooling and noble-gas phasing171
Muscle-derived neurotrophin-3 increases the aggregation of acetylcholine receptors in neuron-muscle co-cultures68
Autoradiographic localization of 2[125I]iodomelatonin binding sites in the gastrointestinal tract of mammals including humans and birds221
The membrane-bound enzyme CD38 exists in two opposing orientations78
Synthesis and characterization of antagonists of cyclic-ADP-ribose-induced Ca2+ release41
Unit responses to bidirectional off-vertical axes rotations in central vestibular and cerebellar fastigial nuclei37
Antihypertensive and anti-arrhythmic effects of an extract of Radix Stephaniae Tetrandrae in the rat69
MicroRNA and messenger RNA profiling reveals new biomarkers and mechanisms for RDX induced neurotoxicity55
Ether stress increases adrenomedullin gene expression and levels in the rat adrenal165
Mechanism of action of prostaglandin E2 in the dog skeletal muscle circulation32
Neuronal plasticity of otolith-related vestibular system147
Ryanodine and the adrenergic, purinergic stimulation in the rat vas deferens smooth muscle: Functional and radioligand binding studies56
Crystallographic snapshots of Aspergillus fumigatus phytase, revealing its enzymatic dynamics109
Epigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways79
Effect of ryanodine on adrenergic stimulation in rat smooth muscle cells35
Cardiac hypertrophy in the newborn delays the maturation of fatty acid β-oxidation and compromises postischemic functional recovery65
Single surgeon's experience with Furlow palatoplasty and the fistula rate255
Influence of stimulation parameters on the release of adenosine, lactate and CO2 from contracting dog gracilis muscle67
Recent development of pineal melatonin and its receptors in humans203
Differential effects of guanosine 5'-O-(3-thiotriphosphate) (GTPγS) on the 2-[125I]iodomelatonin binding sites in the chicken bursa of Fabricius and spleen75
Aprikalim reduces the Na+-Ca2+ exchange outward current enhanced by hyperkalemia in rat ventricular myocytes129
Dedifferentiation of human epidermal keratinocytes induced by UV in vitro53
Effects of prostaglandin E1 on canine nasal vascular and airway resistances32
Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans229
Implementation of cluster analysis for ab initio phasing using the molecular envelope from solution X-ray scattering153
Small Interfering RNA Specific for N-Methyl-D-Aspartate Receptor 2B Offers Neuroprotection to Dopamine Neurons through Activation of MAP Kinase46
NAADP/TPC2/Ca(2+) Signaling Inhibits Autophagy57
Maturation of glutamatergic transmission in the vestibulo-olivary pathway impacts on the registration of head rotational signals in the brainstem of rats72
Erratum: The regional distribution of Thyrotropin releasing hormone, LEU-Enkephalin, MET-Enkephalin, substance P, somatostatin and cholecystokinin in the rat brain and pituitary (Neuropeptides (1991) 19 (287-292))27
Distinct pathways to refill ACh-sensitive internal Ca2+ stores in canine airway smooth muscle64
Inositol trisphosphate receptor Ca2+ release channels197
Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: Relationships to β-amyloid deposition and neurotransmitter abnormalities276
Two Pore Channel 2 (TPC2) Inhibits Autophagosomal-Lysosomal Fusion by Alkalinizing Lysosomal pH107
Acute effects of inhaled sulphur dioxide on pig nasal vascular and airway resistances58
Dedifferentiation of human epidermal keratinocytes induced by combined heat and basic fibroblast growth factor treatment39
Calcium signals and calpain-dependent necrosis are essential for release of coxsackievirus B from polarized intestinal epithelial cells163
Effects of superfusion of morphine and enkephalins on the activity of single units in the spinal trigeminal nucleus and cuneate nucleus of cat38
Neuronal morphology and connections of the gasping center in adult rats76
A transitional course from high school to medical school in a new medical curriculum in Asia: How do the students see it?148
Molecular and cellular aspects of plasticity after neural injury146
The homo-dimeric form of ADP-ribosyl cyclase in solution51
Nitric oxide deficit in chronic intermittent hypoxia impairs large conductance calcium-activated potassium channel activity in rat hippocampal neurons187
Chronic haloperidol treatment decreases preproenkephalin mRNA in the anterior pituitary: A study by solution-hybridization-RNase protection assay55
Quantitative study of the coexpression of Fos and N-methyl-D aspartate (NMDA) receptor subunits in otolith-related vestibular nuclear neurons of rats181
Preventing And Treating Chronic Disorders Using The Modified Vaccination Technique.108
Chronic hypoxia induced down-regulation of angiotensinogen expression in rat epididymis178
Generation and characterization of sodium-dicarboxylate cotransporter-deficient mice120
A cocktail drug therapy for patients with cystic fibrosis?40
Adrenomedullin in the rat testis. II: Its production, actions on inhibin secretion, regulation by follicle-stimulating hormone, and its interaction with endothelin 1 in the Sertoli cell192
Lack of interaction between adenosine-induced vasodilatation and carotid baroreflex-induced changes in sympathetic activity in dog hindlimb artery40
Effect of SIN-1 in rat ventricular myocytes: Interference with β-adrenergic stimulation58
ELECTRON-DENSITY MAPS OF LYSOZYME CALCULATED USING SYNCHROTRON LAUE DATA COMPRISING SINGLES AND DECONVOLUTED MULTIPLES143
A cell permeable NPE caged ADP-ribose for studying TRPM270
The structural basis for activation of plant immunity by bacterial effector protein AvrPto169
Activation of protein kinase C as a modulator of potentiated UK-14304-induced contraction in dog mesentene artery and vein95
Graded recruitment and inactivation of single InsP3 receptor Ca2+-release channels: Implications for quartal Ca2+release216
Ca2+ Signaling Occurs via Second Messenger Release from Intraorganelle Synthesis Sites195
Metabolic syndrome in an Asian population and agents and targets for cardiovascular protection124
A procedure for ab initio phasing of one-wavelength anomalous scattering data from proteins - Combining direct methods with the solvent flattening technique185
Garlic-derived S-allylmercaptocysteine ameliorates nonalcoholic fatty liver disease in a rat model through inhibition of apoptosis and enhancing autophagy76
Postnatal hypoxemia increases angiotensin II sensitivity and up-regulates AT 1a angiotensin receptors in rat carotid body chemoreceptors43
Intracellular adenosine formation and release by freshly-isolated vascular endothelial cells from rat skeletal muscle: effects of hypoxia and/or acidosis64
Aldose reductase deficiency improves wallerian degeneration and nerve regeneration in diabetic thy1-YFP mice199
Measurement of neuropeptides in the brain and spinal cord of Wobbler mouse: A model for motoneuron disease122
The program SAPI and its applications. II. The combination of Patterson superposition and direct methods190
Why is the itchyness following mosquito bite?118
Laser-induced fusion of human embryonic stem cells with optical tweezers99
Dual effect of cobra cardiotoxin on vascular smooth muscle and endothelium121
DANGER, a novel regulatory protein of inositol 1,4,5-trisphosphate-receptor activity177
Two distinct pathways for refilling Ca2+ stores in permeabilized bovine trachealis muscle56
Reactive astrocytes as potential manipulation targets in novel cell replacement therapy of Parkinson's disease183
Postsynaptic signaling of new players at the neuromuscular junction43
Pineal melatonin-immune system interaction45
Effect of steroid hormones on the process of natural sex reversal in the rice-field eel, Monopterus albus (Zuiew)60
Inhibition of pH homeostasis stimulates adenosine output from dog skeletal muscle102
Acidosis antagonizes intracellular calcium response to κ-opioid receptor stimulation in the rat heart59
Melatonin MT 1 receptor-induced transcriptional up-regulation of p27 Kip1 in prostate cancer antiproliferation is mediated via inhibition of constitutively active nuclear factor kappa B (NF-κB): Potential implications on prostate cancer chemoprevention and therapy76
Structures of S. aureus thymidylate kinase reveal an atypical active site configuration and an intermediate conformational state upon substrate binding47
Interaction of caveolin-1, nitric oxide, and nitric oxide synthases in hypoxic human SK-N-MC neuroblastoma cells176
Crystal structures of Fms1 and its complex with spermine reveal substrate specificity177
Identification of the Jak/Stat Proteins as Novel Downstream Targets of EphA4 Signaling in Muscle: Implications in the regulation of acetylcholinesterase expression75
The mechanisms of enhancement and inhibition of field stimulation responses of guinea-pig vas deferens by prostacyclin analogues181
Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase245
The autocrine human secreted PDZ domain-containing protein 2 (sPDZD2) induces senescence or quiescence of prostate, breast and liver cancer cells via transcriptional activation of p53155
Effect of melatonin on salt gland and kidney function of gulls, Larus glaucescens67
Selective knockdown of gene expression of N-methyl-D-aspartate receptor one ameliorates parkinsonian motor symptom in 6-hydroxydopamine-lesioned rats94
Nitric oxide inhibits delayed rectifier potassium currents in cultured hippocampal neurons via S-nitrosylation203
Autonomic nervous control of myoepithelial cells and secretion in submandibular gland of anaesthetized dogs182
Protein-protein interaction of FHL2, a LIM domain protein preferentially expressed in human heart, with hCDC4766
颈动脉体的生理和病理功能73
Effects of parasympathetic nerve stimulation on intracapsular and intraductal pressures of the submandibular gland in anaesthetized dogs113
Thalamocortical and corticothalamic interaction in the auditory system152
Cold exposure or norepinephrine injections altered melatonin levels in the quail retina68
Adrenomedullin increases ciliary beat frequency and decreases muscular contraction in the rat oviduct193
New Perspectives in Vestibulo-Auditory Neurobiology.106
17D yellow fever vaccine virus envelope protein expressed by recombinant baculovirus is antigenically indistinguishable from authentic viral protein100
2[125I]Iodomelatonin binding and interaction with β-adrenergic signaling in chick heart/coronary artery physiology148
Studies on relationship between testicular capsule and sperm transport in rat testis30
Pre- and postnatal development of the vestibular system. In: W.Q. Cai (Ed), Chapter 11. Science Publisher, Beijing; pp90
ABS: A program to determine absolute configuration and evaluate anomalous scatterer substructure233
Redistribution of cytochrome C is not an essential requirement in C2-ceramide induced apoptosis in HL-60 cells107
Biopsy studies on the natural sex reversal in Monopterus albus (Pisces: Teleostei)114
Chloride and depolarization by acetylcholine in canine airway smooth muscle60
TNF-alpha promotes c-REL/DeltaNp63alpha interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck61
The effects of melatonin and Ginkgo biloba extract on memory loss and choline acetyltransferase activities in the brain of rats infused intracerebroventricularly with β-amyloid 1-4065
Inhibition of cardiomyocytes differentiation of mouse embryonic stem cells by CD38/cADPR/Ca2+ signaling pathway77
Differential expression of GABA receptor subunit messenger ribonucleic acids and immunoreactivity in the rat neostriatum during postnatal development233
Decreased affinity of k-receptor binding during reperfusion following ischaemic preconditioning in the rat heart56
Molecular Evolution of GPCRs: Secretin/secretin receptors51
Low-resolution molecular replacement using a six-dimensional search161
Transforming growth factor-β signal transduction in epithelial cells35
Corticofugal Gating of Auditory Information in the Thalamus: An In Vivo Intracellular Recording Study174
Responses of respiratory modulated and tonic units in the retrotrapezoid nucleus to CO 260
Computational interpretation of the stereoselectivity for a dirhodium tetracarboxylate-catalyzed amidation reaction78
High-pressure cryocooling for capillary sample cryoprotection and diffraction phasing at long wavelengths184
Chronic hypoxia upregulates the expression and function of AT1 receptor in rat carotid body28
The effect of streptozotocin-diabetes on β-endorphin level and proopiomelanocortin gene expression in the rat pituitary64
Corticothalamic synchronization leads to c-fos expression in the auditory thalamus92
ATP and adenosine in the regulation of skeletal muscle blood flow during exercise43
The first plant acyl-CoA-binding protein structures: the close homologues OsACBP1 and OsACBP2 from rice182
Solution structures, dynamics, and lipid-binding of the sterile α-motif domain of the deleted in liver cancer 2195
The effects of ageing on the responses in HIF-1 binding and adrenomedullin gene expression in the rat lung to acute hypoxia86
Amplification of alpha adrenergic vasoconstriction in canine isolated mesenteric artery and vein63
Two pore channel 2 differentially modulates neural differentiation of mouse embryonic stem cells54
Striatal neurons but not nigral dopaminergic neurons in neonatal primary cell culture express endogenous functional N-methyl-D-aspartate receptors88
Chronic hypoxia enhances endothelin-1-induced intracellular calcium elevation in rat carotid body chemoreceptors and up-regulates ETA receptor expression195
Crystal structure of mammalian cysteine dioxygenase: A novel mononuclear iron center for cysteine thiol oxidation179
Human cystic fibrosis airway epithelia have reduced Cl - conductance but not increased Na + conductance108
Modulation of 2[125I]iodomelatonin binding sites in the guinea pig spleen by melatonin injection is dependent on the dose and period but not the time174
Raloxifene relaxes rat pulmonary arteries and veins: Roles of gender, endothelium, and antagonism of Ca2+ influx124
Direct phasing of one-wavelength anomalous-scattering data194
Impaired G(s)α and adenylyl cyclase cause β-adrenoceptor desensitization in chronically hypoxic rat hearts139
Blockade of TCFβ3 up-regulation of p27(Kip1) and p21(Cip1) by expression of RasN17 in epithelial cells30
Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling50
Characterization of multiple ion channels in cultured human cardiac fibroblasts119
Mechanistic basis of excitation-contraction coupling in human pluripotent stem cell-derived ventricular cardiomyocytes revealed by Ca2+ spark characteristics: direct evidence of functional Ca2+-induced Ca2+ release107
Small molecule-mediated directed differentiation of human embryonic stem cells toward ventricular cardiomyocytes66
Intracellular recordings from Deiters' neurons in response to saccular and oculomotor nucleus stimulations68
Binding sites for 2-[125I]iodomelatonin in the adrenal gland58
Elevation of pineal melatonin secretion by electrical stimulation of the cervical sympathetic trunk in rabbits71
Maturation profile of inferior olivary neurons expressing ionotropic glutamate receptors in rats: role in coding linear accelerations203
Decrease of enkephalins in cerebellum during Wobbler mouse motoneuron disease60
Cardioprotective effects of melatonin against myocardial injuries induced by chronic intermittent hypoxia in rats82
Structural Basis for Human PECAM-1-Mediated Trans-homophilic Cell Adhesion131
Bilateral otolith contribution to spatial coding in the vestibular system.196
Induced pluripotent stem cells and neurological disease models30
Crystal structure of a heat-resilient phytase from Aspergillus fumigatus, carrying a phosphorylated histidine132
Enhanced ROS generation mediated by alzheimer's disease presenilin regulation of InsP 3R Ca 2+ signaling177
CD38 and ADP-ribosyl cyclase catalyze the synthesis of a dimeric ADP- ribose that potentiates the calcium-mobilizing activity of cyclic ADP-ribose80
Structure of human MRG15 chromo domain and its binding to Lys36-methylated histone H3188
c-fos expression in the auditory thalamus is triggered by corticofugal projections139
Cutting edge: Granulocyte-macrophage colony-stimulating factor is the major CD8 + T cell-derived licensing factor for dendritic cell activation56
Tonic influence of the caudal ventrolateal medulla on the rostral ventrolateral medulla in spontaneously hypertensive and normotensive Wistar Kyoto rats84
A derivative of NADP mobilizes calcium stores insensitive to inositol trisphosphate and cyclic ADP-ribose39
Impaired paracrine effect of endothelin-1 on vascular smooth muscle in streptozotocin-diabetic: Rats38
Isoproterenol stimulates 5′-AMP-activated protein kinase and fatty acid oxidation in neonatal hearts74
Role of the atypical protein kinase Cζ in regulation of 5′-AMP-activated protein kinase in cardiac and skeletal muscle36
Aldose reductase regulates hepatic peroxisome proliferator-activated receptor α phosphorylation and activity to impact lipid homeostasis220
A single protein immunologically identified as CD38 displays NAD+ glycohydrolase, ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activities at the outer surface of human erythrocytes56
SAD phasing by combination of direct methods with the Solve/Resolve procedure204
Effects of angiotensin II on the spontaneous activity of rostral ventrolateral medullary cardiovascular neurons and blood pressure in spontaneously hypertensive rats187
Receptor-mediated modulation of avian caecal muscle contraction by melatonin: Role of tyrosine protein kinase175
Cyclic ADP-ribose: A calcium mobilizing metabolite of NAD+91
Ceftriaxone ameliorates motor deficits and protects dopaminergic neurons in 6-hydroxydopamine-lesioned rats58
Possible role of cyclic nucleotides in the mechanism of the protective effect of methylprednisolone on the hypoxic heart113
Plant alkaloids, tetrandrine and hernandezine, inhibit calcium-depletion stimulated calcium entry in human and bovine endothelial cells51
Effect of testicular capsulotomy on fertility of rats168
Chinese herbs and herbal extracts for neuroprotection of dopaminergic neurons and potential therapeutic treatment of Parkinson's disease259
Acetylcholine induces contractile and relaxant effects in canine nasal venous systems167
α-Adrenoceptor subtypes of dog saphenous vein: Another unusual property58
Structure of the influenza virus A H5N1 nucleoprotein: Implications for RNA binding, oligomerization, and vaccine design93
mt1 receptor-mediated antiproliferative effects of melatonin on the rat uterine antimesometrial stromal cells186
Ontogeny of 2- 125I Iodomelatonin binding sites in the chicken (Gallus Domesticus) kidney and spleen.117
Coexpression of GABA BR1 and GABA BR2 receptor subunits in the rat vestibular nucleus140
Characterization of the human 36-kDa carboxyl terminal LIM domain protein (hCLIM1)76
Analysis of submicromolar concentrations of adenosine in plasma using reversed phase high-performance liquid chromatography55
Effect of aging on the expression of adrenomedullin and its receptor component proteins in the male reproductive system of the rat167
Prediction of Protein-Protein Interactions Based on Molecular Interface Features and the Support Vector Machine53
Remifentanil preconditioning protects against ischemic injury in the intact rat heart194
Modification of excitation-contraction coupling in cat ventricular myocardium following endocardial damage50
Combining solution wide-angle X-ray scattering and crystallography: Determination of molecular envelope and heavy-atom sites187
Proteomic Analysis of Human Pluripotent Stem Cell-Derived, Fetal and Adult Ventricular Cardiomyocytes Reveals Pathways Crucial for Cardiac Metabolism and Maturation105
Electrical stimulation of pneumotaxic center: Activation of fibers and neurons64
Uncoupling Protein-2 Mediates DPP-4 Inhibitor-Induced Restoration of Endothelial Function in Hypertension Through Reducing Oxidative Stress78
High-level expression of recombinant Aplysia ADP-ribosyl cyclase in Pichia pastoris by fermentation39
Expression of hypoxia-inducible factor-1α in human periodontal tissue201
Spontaneous activity of otolith-related vestibular nuclear neurons in the decerebrate rat45
Hypoxia-inducible factor-1: A molecular hint of physiological changes in the carotid body during long-term hypoxemia?122
Possible relationship between cyclic GMP (cGMP) and flavin mononucleotide (FMN) in the isolated perfused rat heart91
Activation of local renin-angiotensin system by chronic hypoxia in rat pancreas184
Protein kinase CK2, cystic fibrosis transmembrane conductance regulator, and the ΔF508 mutation. F508 deletion disrupts a kinase-binding site (Journal of Biological Chemistry (2007) 282, (10804-10813))31
The reaction mechanism for CD38. A single intermediate is responsible for cyclization, hydrolysis, and base-exchange chemistries55
The role of adrenomedullin in the cardiovascular system111
Effects of NO Donors SNP and DEA on L-type calcium currents in cultural hippocampal neurons112
Differential expression of Toll-like receptor 4 in healthy and diseased human gingiva77
Inhibition of protein kinase CK2 closes the CFTR Cl channel, but has no effect on the cystic fibrosis mutant Δf508-CFTR132
Adrenomedullin is a regulated modulator of neonatal cardiomyocyte hypertrophy in vitro174
Anti-arrhythmic Effect of κ -opioid Receptor Stimulation in the Perfused Rat Heart: Involvement of a cAMP-dependent Pathway36
Dynamics and directional sensitivity of neck muscle spindle responses to head rotation55
Envelope protein sequences of dengue virus isolates TH-36 and TH-Sman, and identification of a type-specific genetic marker for dengue and tick-borne flaviviruses53
Changes in met-enkephalin and β-endorphin contents in the hypothalamus and the pituitary in diabetic rats: Effects of insulin therapy28
Protective effect of polysaccharides-enriched fraction from Angelica sinensis on hepatic injury134
Chromosomal mapping of a skeletal muscle specific LIM-only protein FHL3 to the distal end of the short arm of human chromosome 179
Sodium/myo-inositol cotransporter-1 is essential for the development and function of the peripheral nerves156
Cobalt chloride pretreatment promotes cardiac differentiation of human embryonic stem cells under atmospheric oxygen level193
Role of nitric oxide in the regulation of fibrogenic factors in experimental liver fibrosis in mice141
Adrenomedullin peptide: Gene expression of adrenomedullin, its receptors and receptor activity modifying proteins, and receptor binding in rat testis - Actions on testosterone secretion124
B-Raf and C-Raf are required for Ras-stimulated p42 MAP kinase activation in Xenopus egg extracts76
Calpain-cleaved type 1 inositol 1,4,5-trisphosphate receptor (InsP3R1) has InsP3-independent gating and disrupts intracellular Ca2+ homeostasis52
Adrenomedullin is both proinflammatory and antiinflammatory: Its effects on gene expression and secretion of cytokines and macrophage migration inhibitory factor in NR8383 macrophage cell line133
Norepinephrine release in rat vas deferens. Effect of rauwolscine and BHT 92057
Sensitization of calcium-induced calcium release by cyclic ADP-ribose and calmodulin182
Nasal blood flow and airway resistance. Canine study85
Differential expression of NMDA and AMPA/KA receptor subunits in the inferior olive of postnatal rats205
Acidic residues at the active sites of CD38 and ADP-ribosylt cyclase determine nicotinic acid adenine dinucleotide phosphate (NAADP) synthesis and hydrolysis activities190
The morphology and connections of neurons in the gasping centre of adult rats38
Differential Expression of α-Amino-3-Hydroxy-5-Methyl-4-Isoxazole- Propionate Glutamate Receptors in the Rat Striatum during Postnatal Development57
The gastrointestinal system: A site of melatonin paracrine action163
Pyridine nucleotide metabolites stimulate calcium release from sea urchin egg microsomes desensitized to inositol trisphosphate47
Unusual α-adrenoceptor subtype in canine saphenous vein: comparison to mesenteric vein99
Structural basis for the mechanistic understanding of human CD38-controlled multiple catalysis209
Application of the Ps-function method to macromolecular structure determination99
Activation of mitochondrial ATP-sensitive potassium channels delays ischemia-induced cellular uncoupling in rat heart43
Cholinergic neurons expressing neuromedin K receptor (NK3) in the basal forebrain of the rat: A double immunofluorescence study79
Identification of BDNF in nestin-expressing astroglial cells in the neostriatum of MPTP-treated mice89
Role of STIM1 in survival and neural differentiation of mouse embryonic stem cells independent of Orai1-mediated Ca2 + entry63
Expression of HIF-1α, VEGF and VEGF receptors in the carotid body of chronically hypoxic rat125
Spontaneous discharge and response characteristics of central otolith neurons of rats during postnatal development182
Spontaneous activity and barosensitivity of the barosensitive neurons in the rostral ventrolateral medulla of hypertensive rats induced by transection of aortic depressor nerves150
Corticofugal projection inhibits the auditory thalamus through the thalamic reticular nucleus231
Vacuolin-1 potently and reversibly inhibits autophagosome-lysosome fusion by activating RAB5A74
Important role of ventromedial hypothalamic carnitine palmitoyltransferase-1a in the control of food intake56
Changes in adenosine release and blood flow in the contracting dog gracilis muscle80
The Inhibitory Effect of Adrenomedullin in the Rat Ileum: Cross-Talk with β3-Adrenoceptor in the Serotonin-Induced Muscle Contraction25
Signaling Networks of Activated Oncogenic and Altered Tumor Suppressor Genes in Head and Neck Cancer32
Synergistic effect of osmotic and oxidative stress in slow-developing cataract formation216
Calcium signaling: NAADP ascends as a new messenger51
Cholinergic lesions of the rat brain by ibotenic acid and 192 igG- saporin: Effects on somatostatin, substance P and neuropeptide Y levels in the cerebral cortex and the hippocampus68
Cross-talk between the Smad1 and Ras/MEK signaling pathways for TCFβ39
The first batch of graduates of a new medical curriculum in Asia: How their teachers see them207
Structure and enzymatic functions of human CD38164
A Single Residue at the Active Site of CD38 Determines Its NAD Cyclizing and Hydrolyzing Activities186
The functional role of K+-ATPase in proton transport by gastric microsomal vesicles.46
Importin-mediated retrograde transport of CREB2 from distal processes to the nucleus in neurons61
Effects of κ-opioid receptor stimulation in the heart and the involvement of protein kinase C160
The gene expression of adrenomedullin, calcitonin-receptor-like receptor and receptor activity modifying proteins (RAMPs) in CCl4-induced rat liver cirrhosis46
Calcium mobilization by dual receptors during fertilization of sea urchin eggs49
Cross talk between plasma membrane and sarcoplasmic reticulum in canine airway smooth muscle51
Protein kinase CK2, cystic fibrosis transmembrane conductance regulator, and the ΔF508 mutation: F508 deletion disrupts a kinase-binding site122
Phospholamban as a Crucial Determinant of the Inotropic Response of Human Pluripotent Stem Cell–Derived Ventricular Cardiomyocytes and Engineered 3-Dimensional Tissue Constructs80
Opposite effects of fear conditioning and extinction on dendritic spine remodelling113
Ventilatory response of hypercapnia in the unanesthetized, decerebrate, newborn rat110
Synthesis and biological evaluation of nicotinamide adenine dinucleotides analogues as inhibitors of CD3859
Similarities in amino acid sequences of Aplysia ADP-ribosyl cyclase and human lymphocyte antigen CD3838
Alterations in acetylcholinesterase and choline acetyltransferase activities and neuropeptide levels in the ventral spinal cord of the Wobbler mouse during inherited motoneuron disease212
Melatonin-induced inhibition of proliferation and G 1/S cell cycle transition delay of human choriocarcinoma JAr cells: Possible involvement of MT 2 (MEL(1B)) receptor47
Role of the endocardium in excitation - contraction coupling in isolated cat papillary muscle29
2[125I]Iodomelatonin binding sites in spleens of guinea pigs108
Autonomic nervous control of venous pressure and secretion in submandibular gland of anesthetized dogs145
Signaling mechanisms of melatonin in antiproliferation of hormone-refractory 22Rv1 human prostate cancer cells: Implications for prostate cancer chemoprevention263
Louping ill virus envelope protein expressed by recombinant baculovirus and vaccinia virus fails to stimulate protective immunity63
Systems-level quantification of division timing reveals a common genetic architecture controlling asynchrony and fate asymmetry71
Characterizations and comparisons of eupnoea and gasping in neonatal rats177
Macromolecular phasing119
Modulation of 2-[125I]iodomelatonin binding in the guinea pig spleen by guanine nucleotides and cations148
Widespread occurrence in animal tissues of an enzyme catalyzing the conversion of NAD+ into a cyclic metabolite with intracellular Ca2+-mobilizing activity35
Production and hydrolysis of cyclic ADP-ribose at the outer surface of human erythrocytes57
Hydrogen peroxide produced by two amino acid oxidases mediates antibacterial actions49
Alloxan-induced diabetes and the pineal gland: Differential effects on the levels of pineal N-acetylserotonin, pineal melatonin, and serum melatonin72
The bicyclic intermediate structure provides insights into the desuccinylation mechanism of human sirtuin 5 (SIRT5)95
Erratum: Translocation of a human focal adhesion LIM-only protein, FHL2, during myofibrillogenesis and identification of LIM2 as the principal determinant of FHL2 focal adhesion localization (Cell Motility and the Cytoskeleton (2001) 48 (11-23))26
Direct-method-aided phasing of MAD data196
The effect of systemic hypoxia on interstitial and blood adenosine, AMP, ADP and ATP in dog skeletal muscle204
Crystal structure of the FK506 binding domain of Plasmodium falciparum FKBP35 in complex with FK50674
A molecular perspective of the genetic relationships of G-protein coupled melatonin receptor subtypes202
Structure determination of a 16.8 kDa copper protein at 2.1 a resolution using anomalous scattering data with direct methods181
Intracellular alkalinization induces cytosolic Ca2+ increases by inhibiting sarco/endoplasmic reticulum Ca2+-ATPase (SERCA)83
Structural basis for formation and hydrolysis of the calcium messenger cyclic ADP-ribose by human CD38189
Activating PPAR  Prevents Post-Ischemic Contractile Dysfunction in Hypertrophied Neonatal Hearts84
Metabolic response to an acute jump in cardiac workload: Effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation61
The patch-clamp and planar lipid bilayer techniques: Powerful and versatile tools to investigate the CFTR Cl- channel154
Melatonin reduces hippocampal β-amyloid generation in rats exposed to chronic intermittent hypoxia135
The pattern of cortical dysfunction in a mouse model of a schizophrenia-related microdeletion79
Evidence for a causal role of CD38 expression in granulocytic differentiation of human HL-60 cells172
Myocardial recovery following hypoxia in isolated hearts perfused with various combinations of glucose (G), Insulin (I) and potassium (K)105
Alterations of mRNA levels of α1-adrenoceptor subtypes with maturation and ageing in different rat blood vessels31
The coding of head orientations in neurons of bilateral vestibular nuclei of cats after unilateral labyrinthectomy: Response to off-vertical axis rotation76
bcl-2 protects HL-60 cells from apoptosis by stabilizing their intracellular calcium pools48
Chronic central leptin decreases food intake and improves glucose tolerance in diet-induced obese mice independent of hypothalamic malonyl CoA levels and skeletal muscle insulin sensitivity66
Effect of tilt on the response of neuronal activity within the cat vestibular nuclei during slow and constant velocity rotation70
Effect of eccentric contraction-induced injury on force and intracellular pH in rat skeletal muscles40
Transgenic mouse and chemical lesion approaches to the study of Alzheimer's disease163
Effects of testosterone on 2[125I]iodemolatonin binding sites in the rat corpus epididymidis82
Electrophysiological properties of rostral ventrolateral medulla cardiovascular neurons in neurogenic hypertensive rats96
Possible functions of adrenomedullin from the seminal fluid in the female reproductive tract of the rat57
Editorial overview18
Structural determinants of nicotinic acid adenine dinucleotide phosphate important for its calcium-mobilizing activity39
Erratum: Structural basis for modulation of Kv4 K + channels by auxiliary KChIP subunits (Nature Neuroscience (2007) 10 (32-39))242
S-allylmercaptocysteine reduces carbon tetrachloride-induced hepatic oxidative stress and necroinflammation via nuclear factor kappa B-dependent pathways in mice240
TRPM7 channels regulate proliferation and adipogenesis in 3T3-L1 Preadipocytes47
Wide distribution of an enzyme that catalyzes the hydrolysis of cyclic ADP-ribose57
Calcium homeostasis in rat cardiomyocytes during chronic hypoxia: A time course study77
Differential expression of N-methyl-D-aspartate receptor subunit messenger ribonucleic acids and immunoreactivity in the rat neostriatum during postnatal development50
An in vivo intracellular study of auditory thalamic neurons113
Cardiovascular effects of Radix Stephaniae Tetrandreae - a comparison with its main component, tetrandrine144
Expression and functions of vasoactive substances regulated by hypoxia-inducible factor-1 in chronic hypoxemia128
The role of autoimmunologists in investigating and treating autoimmune disorders170
Polyol pathway mediates iron-induced oxidative injury in ischemic-reperfused rat heart195
Decreased large conductance Ca2+-activated K+ channel activity in dissociated CA1 hippocampal neurons in rats exposed to perinatal and postnatal hypoxia173
Determination of endogenous levels of cyclic ADP-ribose in rat tissues65
Differential expression of AMPA receptor subunits in substance P receptor-containing neurons of the caudate-putamen of rats55
'Biological Signals' to 'Biological Signals and Receptors'47
κ-Opioid receptor stimulation increases the expression of NA+-H+ exchange gene in the heart133
Crystal structure of a 1:1:1 molecular complex of (R)-(+)-2,2'-dihydroxy-1,1'-binaphthyl, N,N,N',N'-tetra(2-butyl)terephthalamide, and methanol193
Isoproterenol amplifies 17β-estradiol-mediated vasorelaxation: Role of endothelium/nitric oxide and cyclic AMP53
Comparative analysis of the NS 1 gene sequences of dengue-1 viruses prototype Hawaii strain and Thai isolate TH-Sman, and determination of the intratypic variation of NS 1 protein among dengue-1 viruses94
Crystal structure of Aplysia ADP ribosyl cyclase, a homologue of the bifunctional ectozyme CD3862
Modulatory effect of cortical activation on the lemniscal auditory thalamus of the guinea pig204
Multiple Ca2+ signaling pathways regulate intracellular Ca 2+ activity in human cardiac fibroblasts117
Inhibition of malonyl-CoA decarboxylase reduces the inflammatory response associated with insulin resistance66
Mode switching is the major mechanism of ligand regulation of InsP 3 receptor calcium release channels210
Tyrosine kinase receptor immunoreactivity in trigeminal mesencephalic and motor neurons following transection of masseteric nerve of the rat191
Preimplantation antagonism of adrenomedullin action compromises fetoplacental development and reduces litter size173
Epigenetic regulation of the electrophysiological phenotype of human embryonic stem cell-derived ventricular cardiomyocytes: Insights for driven maturation and hypertrophic growth70
Calcium signalling of human pluripotent stem cell-derived cardiomyocytes58
Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe54
Time course of cortically induced fos expression in auditory thalamus and midbrain after bilateral cochlear ablation212
Cyclic ADP ribose is a novel regulator of intracellular Ca 2+ oscillations in human bone marrow mesenchymal stem cells165
Transient activation of P38 MAP kinase and up-regulation of Pim-1 kinase in cardiac hypertrophy despite no activation of AMPK48
Differential expression of AMPA receptor subunits in dopamine neurons of the rat brain: A double immunocytochemical study190
Modulation of CD157 expression in multi-lineage myeloid differentiation of promyelocytic cell lines54
Flexibility between the protease and helicase domains of the dengue virus NS3 protein conferred by the linker region and its functional implications64
Voluntary oral feeding of rats not requiring a very high fat diet is a clinically relevant animal model of non-alcoholic fatty liver disease (NAFLD)117
Control of nasal vasculature and airflow resistance in the dog84
Age-related and diurnal changes in met5-enk-arg6-phe7 and met5-enkephalin contents of pituitary and rat brain structures68
Ephrin-B1 Reverse Signaling Activates JNK through a Novel Mechanism That Is Independent of Tyrosine Phosphorylation57
Effects of chronic captopril treatment on the electrical-microstimulation-induced blood pressure changes and electrophysiological properties of cardiovascular neurons in the rostral ventrolateral medulla of the spontaneously hypertensive rat41
Diversity of promoter elements in a Geobacter sulfurreducens mutant adapted to disruption in electron transfer49
Comparison of the gene expression profiles of human fetal cortical astrocytes with pluripotent stem cell derived neural stem cells identifies human astrocyte markers and signaling pathways and transcription factors active in human astrocytes155
Local hypoxia does not elevate adenosine output from isolated gracilis muscle in anaesthetised dogs80
Functional TRPV and TRPM channels in human preadipocytes53
Effect of photic manipulation on the level of melatonin in the retinas of frogs (Rana tigrina regulosa)67
Influences of sex and saline intake on diurnal changes in plasma melatonin and osmoregulatory hormones of Pekin ducks (Anas platyrhynchos)191
Intermedin attenuates LPS-induced inflammation in the rat testis62
Bronchial circulation: a constant flow autoperfusion method for assessing its vasomotor activity and the effect of epinephrine27
Co-expression of prepro-adrenomedullin with a putative adrenomedullin receptor gene in vascular smooth muscle49
Expression of TrkA, TrkB and TrkC receptors in the central pathway of trigeminal proprioception in the rat117
Spontaneous properties of otolith-related vestibular nuclear neurons in the decerebrate rats93
Effects of autonomic nerve stimulation on nasal venous resistance in anaesthetized dogs75
Structural studies of intermediates along the cyclization pathway of aplysia ADP-ribosyl cyclase209
The striatal GABA-ergic neurons expressing substance P receptors in the basal ganglia of mice87
Analysis of different strategies adapted by two cassava cultivars in response to drought stress: ensuring survival or continuing growth158
L-NAME inhibits Mg2+-induced rat aortic relaxation in the absence of endothelium174
Expression, purification and preliminary crystallographic analysis of recombinant human small glutamine-rich tetratricopeptide-repeat protein54
Evaluation of reflection intensities for the components of multiple Laue diffraction spots. II. Using the wavelength-normalization curve172
Translocation of a human focal adhesion LIM-only protein, FHL2, during myofibrillogenesis and identification of LIM2 as the principal determinants of FHL2 focal adhesion localization59
Melatonin: A chemical photoperiodic signal with clinical significance in humans182
Prejunctional α2-adrenergic properties of S-3341 (dicyclopropylmethyl)amino-2-Δ-2-oxazoline: A comparison with clonidine60
Improving the quality of cases for problem-based learning (PBL): experience and feedback from Year 1 medical students, University of Hong Kong112
Receptors of glutamate and neurotrophin in vestibular neuronal functions165
The effect of aging on the response of striatal preproenkephalin and preprotachykinin mRNA contents to chronic haloperidol treatment in rats: Measurement by solution-hybridization RNase protection assay154
Preparation of cyclic ADP-ribose antagonists and caged cyclic ADP- ribose53
Roles of KATP channels in delayed cardioprotection and intracellular Ca2+ in the rat heart as revealed by κ-opioid receptor stimulation with U50,488H140
Acute systemic hypoxia elevates venous but not interstitial potassium of dog skeletal muscle195
Postassium-stimulated ATPase activity and hydrogen transport in gastric microsomal vesicles44
Human pluripotent stem cell-derived cardiovascular progenitors for heart regeneration70
Fluorescent analogs of NAADP with calcium mobilizing activity41
Gastric adenosine triphosphatases: a review of their possible role in HCl secretion64
Intracerebroventricular leptin administration differentially alters cardiac energy metabolism in mice fed a low-fat and high-fat diet55
SNAP-25 is also an iron-sulfur protein172
Evidence for the existence of a constitutive nitric oxide synthase in vascular smooth muscle166
Role of voltage-gated Na+ channels in hypoxia-induced neuronal injuries153
The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs162
Catalysis-based inhibitors of the calcium signaling function of CD38233
Identification of the enzymatic active site of CD38 by site-directed mutagenesis170
Characterization of the active site of ADP-ribosyl cyclase44
Expressions of angiotensin and cytokine receptors in the paracrine signaling of the carotid body in hypoxia and sleep apnea36
Patch-clamp electrophysiology of intracellular Ca2+ channels75
Medullary neuronal activities in gasping induced by pharyngeal stimulation and hypoxia52
Human pluripotent stem cell-based approaches for myocardial repair: From the electrophysiological perspective119
Comparison of Ca2+ mobilizing activities of cyclic ADP-ribose and inositol trisphosphate46
STRUCTURE DETERMINATION WITH LAUE DIFFRACTION DATA - INCLUDING REFINEMENT WHEN ANOMALOUS SCATTERERS ARE PRESENT194
Power spectral analysis of respiratory responses to pharyngeal stimulation in cats: Comparisons with eupnoea and gasping67
Crystal structure of a new class of glutathione transferase from the model human hookworm nematode Heligmosomoides polygyrus162
Melatonin and melatonin receptors: Recent advances108
Role of dorsal motor nucleus of vagus in gastric function and mucosal damage induced by ethanol in rats160
A simple interspike interval analyzer for study of neuronal spike trains64
T3 reverses the changes in met-enkephalin and β-endorphin contents in the anterior lobe, but not the neuro-intermediate lobe of the pituitary of rats rendered hypothyroid by PTU-treatment74
Developmental expression of NMDA and AMPA receptor subunits in vestibular nuclear neurons that encode gravity-related horizontal orientations145
Reprint of "frequency tuning and firing pattern properties of auditory thalamic neurons: An in vivo intracellular recording from the guinea pig" [Neuroscience 151 (2008) 293-302]{star, open}123
Human pluripotent stem cell-derived cardiomyocytes for heart regeneration, drug discovery and disease modeling: From the genetic, epigenetic, and tissue modeling perspectives53
Determination of dmin and λmin from the intensity distributions of Laue Patterns133
Effects of melatonin in blood gluocose and melatonin receptors in mouse hepatocytes138
In vitro effects of S.3341 on the spontaneous contractile activity of the rat portal vein: Interference with the α-adrenergic stimulation49
Co-regulation of mucosal prostanoids and substance P by indomethacin in rat stomachs60
Structure of Crimean-Congo hemorrhagic fever virus nucleoprotein: superhelical homo-oligomers and the role of caspase-3 cleavage61
Endogenous repair by the activation of cell survival signalling cascades during the early stages of rat parkinsonism36
5-HT excites globus pallidus neurons by multiple receptor mechanisms220
Mechanistic studies of the mitotic activation of Mos39
Purification, partial characterization and crystallization of acucetin, a protein containing both disintegrin-like and cysteine-rich domains released by auto-proteolysis of a P-III-type metalloproteinase AaH-IV from Agkistrodon acutus venom168
The functional expression of a pontine pneumotaxic centre in neonatal rats63
Ab initio phasing using molecular envelope from solution X-ray scattering157
Crystal Structures of Human CD38 in Complex with NAADP and ADPRP53
Direct sensing of intracellular pH by the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel140
Pertussis toxin, but not tyrosine kinase inhibitors, abolishes effects of U-50488H on [Ca2+](i) in myocytes124
The relaxant effect of urocortin in rat pulmonary arteries141
The nasal vascular and airway responses to intracarotid injection of nicotine in the dog27
Induced-fit upon Ligand Binding Revealed by Crystal Structures of the Hot-dog Fold Thioesterase in Dynemicin Biosynthesis62
Intravenous Anesthetic Propofol Inhibits Multiple Human Cardiac Potassium Channels43
Development of neural correlates of linear motion in the rat vestibular nucleus44
Mechanisms of maladaptive responses of peripheral chemoreceptors to intermittent hypoxia in sleep-disordered breathing129
Multiple sites of melatonin action in the reproductive system104
The proNGF-p75NTR-sortilin signalling complex as new target for the therapeutic treatment of Parkinson's disease219
The application of one-wavelength anomalous scattering. I. Combining results of different methods183
The effect of aging on ANP levels in the plasma, heart, and brain of rats173
Elfin is expressed during early heart development132
Endothelial m, and m3 muscarinic receptor subtypes mediate acetylcholine - induced relaxation in rat tail artery25
Gene deletion and pharmacological inhibition of aldose reductase protect against retinal ischemic injury180
An updated phylogenetic analysis of vertebrate melatonin receptor sequences: Reflection on the melatonin receptor nomenclature by the nomenclature subcommittee of the International Union of Pharmacology193
Hepatic response to chronic hypoxia in experimental rat model through HIF-1 alpha, activator protein-1 and NF-kappa B33
Autoradiographic distribution and physiological regulation of 2-[125I]iodomelatonin binding in rat epididymis187
Structure and catalytic mechanism of the thioesterase CalE7 in enediyne biosynthesis69
Nuclear patch-clamp electrophysiology of Ca2+ channels46
Hyporesponsiveness to Ca 2+ of aortic smooth muscle in endotoxin- treated rats: No-dependent and -independent in vitro mechanisms34
Design, Synthesis And Biological Evaluation Of Noncovalent Inhibitors Of Human Cd38 Nadase99
Sodium and proton transport in flagella isolated from sea urchin spermatozoa80
Ablation of gene expression of N-methyl-D-aspartate receptor one by antisense oligonucleotides in striatal neurons in culture174
Morphometric study on Leydig cells in capsulotomized testis of rats189
The role of intracellular pH in the control of adenosine output from red skeletal muscle187
Mechanism-based small molecule probes for labeling CD38 on live cells212
Functional expression of secreted mouse BST-1 in yeast48
Human ether-à-go-go gene potassium channels are regulated by EGFR tyrosine kinase187
Differential effects of pinealectomy on the 2 125I iodomelatonin binding sites in the bursa and spleen of chicken (Gallus domesticus)87
Neuroprotective Mechanism of Lycium barbarum Polysaccharides against Hippocampal-Dependent Spatial Memory Deficits in a Rat Model of Obstructive Sleep Apnea74
Neurotrophin receptor immunostaining in the vestibular nuclei of rats192
Melatonin Attenuates Intermittent Hypoxia-Induced Lipid Peroxidation and Local Inflammation in Rat Adrenal Medulla39
Crystal structure of isoflurane bound to integrin LFA-1 supports a unified mechanism of volatile anesthetic action in the immune and central nervous systems140
Chronic exposure to hypergravity affects thyrotropin-releasing hormone levels in rat brainstem and cerebellum42
Regional and diurnal studies of melatonin and melatonin binding sites in the duck gastro-intestinal tract185
Reduction in somatostatin and substance P levels and choline acetyltransferase activity in the cortex and hippocampus of the rat after chronic intracerebroventricular infusion of β-amyloid (1-40)36
Cyclic ADP ribose activation of the ryanodine receptor is mediated by calmodulin182
Internal GTP stimulates the speract receptor mediated voltage changes in sea urchin spermatozoa membrane vesicles61
Intracellular lactate controls adenosine output from dog gracilis muscle during moderate systemic hypoxia69
Applications of direct methods with single isomorphous replacement or one-wavelength anomalous scattering data117
Effects of guanosine 5'-O-(3-thio-triphosphate) on 2-[125I]iodomelatonin binding in the chicken lung, brain and kidney: Hypothesis of different subtypes of high affinity melatonin receptors61
Response characteristics of neurons in the cat vestibular nuclei during slow and constant velocity off-vertical axes rotations in the clockwise and counterclockwise rotations114
NADPH-diaphorase histochemistry identifies isolated endothelial cells at sites of traumatic injury in the adult rat brain57
Essential Regulation of Cell Bioenergetics by Constitutive InsP 3 Receptor Ca 2+ Transfer to Mitochondria210
Real time analysis of fingerpulse plethysmographic signal and its application on pulse oximetry70
Effect of melatonin suppression on scoliosis development in chickens by either constant light or surgical pinealectomy177
Correction of human phospholamban R14del mutation associated with cardiomyopathy using targeted nucleases and combination therapy75
Cyclic ADP-ribose and its metabolic enzymes186
Cardiac effects of the extract and active components of radix stephaniae tetrandrae: II. Myocardial infarct, arrhythmias, coronary arterial flow and heart rate in the isolated perfused rat heart166
Genetic restoration of aldose reductase to the collecting tubules restores maturation of the urine concentrating mechanism182
The K(Ca) channel as a trigger for the cardioprotection induced by kappa-opioid receptor stimulation –- its relationship with protein kinase C166
Development of the vestibular system107
Co-expression of adrenomedullin and adrenomedullin receptors in rat epididymis: Distinct physiological actions on anion transport71
Effects of sulfhydryl reagents on [3H] inositol trisphosphate binding to dog cerebellar membranes54
Mos mediates the mitotic activation of p42 MAPK in Xenopus egg extracts56
Multilayer X-ray optics at CHESS171
The variable N-terminal region of DDX5 contains structural elements and auto-inhibits its interaction with NS5B of hepatitis C virus111
Characteristics of 2-[125I]iodomelatonin binding sites in the pigeon spleen and modulation of binding by guanine nucleotides70
Evaluation of reflection intensities for the components of multiple Laue diffraction spots by direct methods108
Involvement of pontile NMDA receptors in inspiratory termination in rat63
Evaluation of Reflection Intensities for the Components of Multiple Laue Diffraction Spots by the Maximum-Entropy Method179
Nuclear CD38 in retinoic acid-induced HL-60 cells160
Co-localization of NMDA receptors and AMPA receptors in neurons of the vestibular nuclei of rats175
The application of one-wavelength anomalous scattering. II. An analytical approach for phase determination195
Proton permeability and lipid dynamics of gastric and duodenal apical membrane vesicles57
Neuroprotective effects of neurokinin receptor one in dopaminergic neurons are mediated through Akt/PKB cell signaling pathway63
GTP cyclohydrolase II structure and mechanism53
Brain-derived neurotrophic factor rescues and prevents chronic intermittent hypoxia-induced impairment of hippocampal long-term synaptic plasticity159
Chemical modification of gastric microsomal potassium-stimulated ATPase54
Developmental maturation of ionotropic glutamate receptor subunits in rat vestibular nuclear neurons responsive to vertical linear acceleration148
Mechanisms of calcium signaling by cyclic ADP-ribose and NAADP51
Ionic mechanisms underlying cardiac toxicity of the organochloride solvent trichloromethane148
Brain cholecystokin octopeptide (CCK-8) concentrations: Effect of tryptophan and other serotonergic agents59
Adenosine output from dog gracilis muscle during systemic hypercapnia and/or amiloride-SITS infusion207
Hierarchical and helical self-assembly of ADP-ribosyl cyclase into large-scale protein microtubes161
Dual effects of tetrandrine on cytosolic calcium in human leukaemic HL-60 cells: intracellular calcium release and calcium entry blockade181
Arterial supply, venous drainage and collateral circulation in the nose of the anaesthetized dog67
GABA-B receptor activation in the rat globus pallidus potently suppresses pentylenetetrazol-induced tonic seizures180
Crystal structure of uroporphyrinogen decarboxylase from Bacillus subtilis194
Targeting fatty acid and carbohydrate oxidation - A novel therapeutic intervention in the ischemic and failing heart58
Lung reflexes and nasal vascular resistance in the anaesthetized dog63
Garlic-derived S-allylmercaptocysteine is a hepato-protective agent in non-alcoholic fatty liver disease in vivo animal model171
Evidence for control of adenosine metabolism in rat oxidative skeletal muscle by changes in pH221
Role of cyclooxygenase in ventricular effects of adrenomedullin: Is adrenomedullin a double-edged sword in sepsis?130
Adrenomedullin gene expression and peptide levels in the heart and blood vessels of streptozotocin-diabetic rats70
Response properties of Y group neurons to crossed otolith inputs in the cat117
Electrophysiological properties of neurons in the rostral ventrolateral medulla of normotensive and spontaneously hypertensive rats66
Efficient Demyristoylase Activity of SIRT2 Revealed by Kinetic and Structural Studies105
Capacitative Ca2+ entry in HL-60 cells: tetrandrine and SK & F 96365 as probes107
An Overview of Melatonin and Melatonin Receptors in Birds189
Transplantation of human bone marrow-derived mesenchymal stem cells transfected with ectodysplasin for regeneration of sweat glands156
Zeaxanthin Dipalmitate Therapeutically Improves Hepatic Functions in an Alcoholic Fatty Liver Disease Model through Modulating MAPK Pathway111
Chronic hypoxia modulates the function and expression of melatonin receptors in the rat carotid body226
Structures of R- and T-state Escherichia coli aspartokinase III: Mechanisms of the allosteric transition and inhibition by lysine34
Lycium barbarum polysaccharides therapeutically improve hepatic functions in non-alcoholic steatohepatitis rats and cellular steatosis model121
The C-terminal segment of the cysteine-rich interdomain of Plasmodium falciparum erythrocyte membrane protein 1 determines CD36 binding and elicits antibodies that inhibit adhesion of parasite-infected erythrocytes70
Melatonin as a negative mitogenic hormonal regulator of human prostate epithelial cell growth: Potential mechanisms and clinical significance137
The effect of pinealectomy on scoliosis development in young nonhuman primates70
Functional visualization of the separate but interacting calcium stores sensitive to NAADP and cyclic ADP-ribose21
Changes in melatonin receptors in relation to the development of scoliosis in pinealectomized chickens161
Characterization of a large conductance, cation-selective channel from sea urchin eggs that is sensitive to sulfhydryl reducing agents45
Augmentation of hypoxia-induced nitric oxide generation in the rat carotid body adapted to chronic hypoxia: An involvement of constitutive and inducible nitric oxide synthases204
A simple, cost-effective but highly efficient system for deriving ventricular cardiomyocytes from human pluripotent stem cells85
Probing flecainide block of INa using human pluripotent stem cell-derived ventricular cardiomyocytes adapted to automated patch-clamping and 2D monolayers154
Pontile regulation of ventilatory activity in the adult rat39
Neuroprotective effects of ginsenoside-Rg1 in primary nigral neurons against rotenone toxicity179
Accumulation of ceramide in slow-twitch muscle contributes to the development of insulin resistance in the obese JCR:LA-cp rat50
The effect of adrenomedullin on the L-type calcium current in myocytes from septic shock rats: Signaling pathway144
Chloroform extract of cigarette smoke induces proliferation of human esophageal squamous-cell carcinoma cells: Modulation by β-adrenoceptors213
Proteins and direct methods142
Gain-of-function enhancement of IP3 receptor modal gating by familial Alzheimer's disease-linked presenilin mutants in human cells and mouse neurons200
Inhibitory effect of tetrabutylammonium ions on endothelium/nitric oxide-mediated vasorelaxation60
Intermedin inhibits norepinephrine - induced contraction of rat seminal vesicle51
Adrenomedullin in the rat testis. I: Its production, actions on testosterone secretion, regulation by human chorionic gonadotropin, and its interaction with endothelin 1 in the Leydig cell202
Variations in blood flow on mandibular glandular secretion to autonomic nervous stimulations in anesthetized dogs38
Glucagon and a glucagon-GLP-1 dual-agonist increases cardiac performance with different metabolic effects in insulin-resistant hearts95
Metabolism of cyclic ADP-ribose in opossum kidney renal epithelial cells59
Separation of multiple functions in ventilatory control of pneumotaxic mechanisms48
Absence of MK801-induced inspiratory prolongation in chronically hypoxic rats86
More severe type 2 diabetes-associated ischemic stroke injury is alleviated in aldose reductase-deficient mice177
Why is the left handedness?80
Aging and diurnal rhythms of pineal serotonin, 5-hydroxyindoleacetic acid, norepinephrine, dopamine and serum melatonin in the male rat54
Neurokinin peptides and neurokinin receptors as potential therapeutic intervention targets of basal ganglia in the prevention and treatment of Parkinson's disease182
Tyk2/STAT3 signaling mediates β-amyloid-induced neuronal cell death: Implications in alzheimer's disease48
Modulation of m2 receptors and excitation-contraction coupling in bovine airway smooth muscle35
The influence of substance P and prostanoids in the pathogenesis and adaptive cytoprotection of ethanol in rat stomach88
Central synapse and neuromuscular junction: Same players, different roles71
Urgent search for safe and effective treatments of severe acute respiratory syndrome: Is melatonin a promising candidate drug?125
YAP dysregulation by phosphorylation or DeltaNp63-mediated gene repression promotes proliferation, survival and migration in head and neck cancer89
Adrenomedullin regulates sperm motility and oviductal ciliary beat via cyclic adenosine 5′-monophosphate/protein kinase A and nitric oxide173
Overexpression of Kir2.1 channel in embryonic stem cell-derived cardiomyocytes attenuates posttransplantation proarrhythmic risk in myocardial infarction42
Deletion of aldose reductase leads to protection against cerebral ischemic injury210
Correcting autoimmune anomalies in autoimmune disorders by immunological means, employing the modified vaccination technique188
Cyclic Adenosine 5′-Diphosphate Ribose Analogs without a “Southern” Ribose Inhibit ADP-ribosyl Cyclase–Hydrolase CD3882
Dopaminergic and GABAergic amacrine cells are direct targets of melatonin: Immunocytochemical study of mt1 melatonin receptor in guinea pig retina162
Increased adrenomedullin expression in lungs in endotoxaemia132
Non-cell autonomous cues for enhanced functionality of human embryonic stem cell-derived cardiomyocytes via maturation of sarcolemmal and mitochondrial KATP channels169
Induction of NG108-15 cells differrentiation by human bone marrow stromal cells74
Increased PKA activity and its influence on isoprenaline-stimulated L-type Ca2+ channels in the heart from ovariectomized rats152
Cloning and characterization of muscle-specific kinase in chicken79
Modulation of the voltage-sensitive Na+/H+ exchange in sea urchin spermatozoa through membrane potential changes induced by the egg peptide speract148
Neuropeptide Y suppressed the T3-induced rise in brown fat mitochondrial respiration in hypothyroid rats152
Adenosine and cholinergic-induced gastric contraction in rats90
Evaluation of reflection intensities for the components of multiple Laue diffraction spots. III. Using a real-space density modification method189
Localization of nerve growth factor, neurotrophin-3, and glial cell line-derived neurotrophic factor in nestin-expressing reactive astrocytes in the caudate-putamen of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated C57/B1 mice161
α-syntrophin regulates ARMS localization at the neuromuscular junction and enhances EphA4 signaling in an ARMS-dependent manner47
Melatonin-induced stimulation of rat corpus epididymal epithelial cell proliferation158
Powder to become crystal clear40
Design, synthesis and biological characterization of novel inhibitors of CD38183
Genistein and tyrphostin AG556 inhibit inwardly-rectifying Kir2.1 channels expressed in HEK 293 cells via protein tyrosine kinase inhibition174
Flourescent analogs of cyclic ADP-ribose: Synthesis, spectral characterization, and use125
Requirement of B-Raf, C-Raf, and A-Raf for the growth and survival of mouse embryonic stem cells49
Monitoring cyclic nucleotide metabolism in intact cells by 18O labeling162
Non-identity of cGMP as the guanine nucleotide stimulated to bind to ROS by light and ATP135
Inhibition of serine palmitoyl transferase I reduces cardiac ceramide levels and increases glycolysis rates following diet-induced insulin resistance45
Postnatal development of the spatial coding capacity of otolith neurons: Physiological properties and c-fos expression81
Differential regulation of adrenomedullin gene expression in the fundic and pyloric regions of the rat stomach during acute and chronic starvation199
Effect of N-acetylserotonin on the serum level of thyroid-stimulating hormone in the male rat64
Sleep promotes branch-specific formation of dendritic spines after learning186
Chronic hypoxia inhibits the antihypertensive effect of melatonin on pulmonary artery207
Erratum: Requirement of Ras/MAPK pathway activation by transforming growth factor β for transforming growth factor β1 production in a Smad-dependent pathway (Journal of Biological Chemistry (2000) 275 (30765-30773))26
Endothelium-dependent effect of bradykinin and ATP on rabbit ventricular myocytes151
Role of fatty acid uptake and fatty acid β-oxidation in mediating insulin resistance in heart and skeletal muscle53
Possible retrogenesis observed with fiber tracking: An anteroposterior pattern of white matter disintegrity in normal aging and alzheimer's disease152
Cyclic ADP-ribose is a second messenger in the lipopolysaccharide- stimulated proliferation of human peripheral blood mononuclear cells200
The role of secretin in the cerebellum145
Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake69
The atomic resolution crystal structure of atratoxin determined by single wavelength anomalous diffraction phasing160
Age-related changes in the contents of neuropeptides in the rat brain and pituitary57
Thapsigargin inhibits repletion of phenylephrine-sensitive intracellular Ca++ pool in vascular smooth muscles41
Utilization of neuron-cognitive science for the improvement of language education in Hong Kong117
Cycloxygenase-1 serves a vital hepato-protective function in chemically induced acute liver injury110
Crystal structure of human CD38 extracellular domain200
Mapping heparanase expression in the spinal cord of adult rats173
Cell-Cell Interaction Underlies Formation Of Fluid In The Male Reproductive Tract Of The Rat216
Crystallization and preliminary crystallographic analysis of a new class of glutathione transferase from nematodes165
Attenuated "cross talk" between κ-opioid receptors and β-adrenoceptors in the heart of chronically hypoxic rats90
Structural determination of a cyclic metabolite of NAD+ with intracellular Ca2+-mobilizing activity31
Pituitary contents of beta-endorphin, dynorphin, substance P, cholecystokinin and somatostatin in rats with streptozotocin-induced diabetes173
Effect of cage size on ultradian locomotor rhythms of laboratory mice192
Role of protein kinase C-epsilon in the development of κ-opioid receptor tolerance to U50,488H in rat ventricular myocytes142
Distribution and excitable effects of NOS in rat hippocampal neurons cultured in vitro111
Regulation of cell proliferation by intermediate-conductance Ca 2+-activated potassium and volume-sensitive chloride channels in mouse mesenchymal stem cells144
Negative correlation of age and the levels of pineal melatonin, pineal N-acetylserotonin, and serum melatonin in male rats.59
Exogenous expression of human apoA-I enhances cardiac differentiation of pluripotent stem cells137
Immunohistochemical observation on luteinizing hormone in rat testes before and after testicular capsulotomy167
Regulation of the coupling between activation of muscarinic receptor and calcium influx by calcium stores in bovine tracheal smooth muscle cells88
Mechanism of Ca 2+ Disruption in Alzheimer's Disease by Presenilin Regulation of InsP 3 Receptor Channel Gating188
Fos expression in otolith-related brainstem neurons of postnatal rats following off-vertical axis rotation147
Interaction of cold and starvation in the regulation of plasma corticosterone levels in the male rat62
Intravital imaging of dendritic spine plasticity57
Melatonin ameliorates hippocampal nitric oxide production and large conductance calcium-activated potassium channel activity in chronic intermittent hypoxia221
Sex differences in the serum concentrations of testosterone in mice and hamsters during their critical periods of neural sexual differentiation52
Protein-complex structure completion using IPCAS (Iterative Protein Crystal structure Automatic Solution)43
Expression, purification, crystallization and preliminary X-ray analysis of Plasmodium falciparum GTP:AMP phosphotransferase143
S-SWAT (softer single-wavelength anomalous technique): Potential in high-throughput protein crystallography212
An investigation of the possible site(s) of melatonin action on the brain-gonadal axis: 125I iodomelatonin binding sites in the quail brain and testis under long and short photoperiods41
Roles of calcium in the regulation of apoptosis in HL-60 promyelocytic leukemia cells42
Further study on the role of HSP70 on Ca2+ homeostasis in rat ventricular myocytes subjected to simulated ischemia211
Effect of melatonin on chloride secretion by human colonic T84 cells62
Effects of pharmacological preconditioning with U50488H on calcium homeostasis in rat ventricular myocytes subjected to metabolic inhibition and anoxia134
Recombinant vaccinia virus expressing PrM and E glycoproteins of louping ill virus: Induction of partial homologous and heterologous protection in mice221
Further studies on energized hog gastric microsomes using acridine orange28
Putative melatonin receptors in the male guinea pig kidney.68
Peripheral distribution and gene expression of adrenomedullin in the rat: Possible source of blood adrenomedullin153
A novel cycling assay for nicotinic acid-adenine dinucleotide phosphate with nanomolar sensitivity175
Loss of anion transport without increased sodium absorption characterizes newborn porcine cystic fibrosis airway epithelia160
Effect of sex and age on serum aldosterone and thyroid hormones in the laboratory rat55
The influence of dorsal raphe nucleus stimulation on epileptiform activity in hippocampal neurons during kainic acid induced epilepsy in the rat111
Procedures which acidify the cytoplasm stimulate adenosine release from isolated, perfused gracilis muscle in anaesthetized dogs170
Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38240
Coexpression of adrenomedullin and its receptors in the reproductive system of the rat: effects on steroid secretion in rat ovary174
Green tea polyphenols as an anti-oxidant and anti-inflammatory agent for cardiovascular protection165
Conformational closure of the catalytic site of human CD38 induced by calcium191
Development of T-tubular vacuoles in eccentrically damaged mouse muscle fibres143
Increased neuronal excitability after long-term O2 deprivation is mediated mainly by sodium channels166
Effects of cold exposure or TRH on the serum TSH levels in the iron-deficient rat54
Noninvasive monitoring of diabetes-induced cutaneous nerve fiber loss and hypoalgesia in thy1-YFP transgenic mice191
2-[125I]iodomelatonin-binding sites in the human kidney and the effect of guanosine 5'-0-(3-thiotriphosphate)143
General Anesthetic Isoflurane Modulates Inositol 1,4,5-Trisphosphate Receptor Calcium Channel Opening55
Autonomic nervous control of nasal vasculature and airflow resistance in the anaesthetized dog60
Erratum: Graded recruitment and inactivation of single InsP3 receptor Ca2+-release channels: Implications for quantal Ca2+ release (J Physiol (2006) vol. 573 (645-662))115
Expiratory neural activities in gasping induced by pharyngeal stimulation and hypoxia49
Engineered human pluripotent stem cell-derived cardiac cells and tissues for electrophysiological studies78
Exogenous expression of HIF-1α promotes cardiac differentiation of embryonic stem cells223
Chronic intracerebroventricular exposure to β-amyloid(1-40) impairs object recognition but does not affect spontaneous locomotor activity or sensorimotor gating in the rat45
Crystal structure of NDM-1 reveals a common β-lactam hydrolysis mechanism118
Vestibular function of saccule in cats as indicated by the response of Deiters' nucleus to static tilts49
Lipopolysaccharide and hypoxia-induced HIF-1 activation in human gingival fibroblasts181
TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory86
Secretin and body fluid homeostasis168
Effects of [Sar1, Ile8]-angiotensin II on rostral ventrolateral medulla neurons and blood pressure in spontaneously hypertensive rats179
Melatonin receptors and melatonin inhibition of duck salt gland secretion44
Bronchial circulation: an auto perfusion method for assessing its vasomotor activity and the study of alpha and beta adrenoreceptors in the bronchial artery60
Reflex recruitment of medullary gasping mechanisms in eupnoea by pharyngeal stimulation in cats81
cAMP/Protein Kinase A activates Cystic Fibrosis Transmembrane Conductance Regulator for ATP release from rat skeletal muscle during low pH or contractions76
Effect of testicular capsulotomy on lipid droplets in the seminiferous tubules of rats87
Pharmacology of Cardiac Potassium Channels134
Caged nicotinic acid adenine dinucleotide phosphate. Synthesis and use27
Retinal dopaminergic neurons (A17) expressing neuromedin K receptor (NK3): A double immunocytochemical study in the rat72
Effect of mammalian luteinizing hormone on the natural sex reversal of the rice-field eel, Monopterus albus (Zuiew)91
Effects of hypercapnia and hypoxia on nasal vasculature and airflow resistance in the anaesthetized dog64
Activation and inactivation of Ca 2+ release by NAADP +151
Dynamic conformations of the CD38-mediated NAD cyclization captured in a single crystal146
Cross-talk between the pineal gland and immune system38
Emerging role of cyclic ADP-ribose (cADPR) in smooth muscle48
Nonendothelial aortic source of nitric oxide in Wistar-Kyoto normotensive and spontaneous hypertensive rats.66
Melatonin and 2[125I]iodomelatonin binding sites in the human colon190
Nestin-containing cells express glial fibrillary acidic protein in the proliferative regions of central nervous system of postnatal developing and adult mice185
Attenuated transforming growth factor beta signaling promotes nuclear factor-kappaB activation in head and neck cancer108
Cloning and expression of a novel neurotrophin, NT-7, from carp57
The influence of lactic acid on adenosine release from skeletal muscle in anaesthetized dogs75
PTHGRN: unraveling post-translational hierarchical gene regulatory networks using PPI, ChIP-seq and gene expression data87
Functional interplay between melatonin receptor-mediated antiproliferative signaling and androgen receptor signaling in human prostate epithelial cells: Potential implications for therapeutic strategies against prostate cancer115
ADP-ribosyl cyclase and CD38 catalyze the synthesis of a calcium- mobilizing metabolite from NADP +171
Physiological functions of cyclic ADP-ribose and NAADP as calcium messengers46
Potentiation of calcium- and caffeine-induced calcium release by cyclic ADP-ribose35
Genomic sequence of the structural proteins of louping ill virus: Comparative analysis with tick-borne encephalitis virus72
Baroreflex responsiveness of rostral ventrolateral medullary cardiovascular neurons in neurogenic hypertensive rats87
Response of medial medullary reticular neurons to otolith stimulation during bidirectional off-vertical axis rotation of the cat164
Carotid body AT4 receptor expression and its upregulation in chronic hypoxia137
Some age-related changes in pituitary-adrenal function in the male laboratory rat63
The dynamics of cGMP metabolism in neuroblastoma N1E-115 cells determined by 18O labeling of guanine nucleotide α-phosphoryls144
Synapse development and plasticity: roles of ephrin/Eph receptor signaling56
An ontogenic study of adrenomedullin gene expression in the rat lung, adrenal, kidney, and heart126
Pontine cholinergic respiratory depression in neonatal and young rats170
Mechanism of cyclizing NAD to cyclic ADP-ribose by ADP-ribosyl cyclase and CD38134
Increased cAMP and cGMP hydrolytic flux with cholinergic and beta-adrenergic stimulation of rat parotid secretion88
CFTR-deficient pigs display peripheral nervous system defects at birth59
Blocking effect and crystal structure of natrin toxin, a cysteine-rich secretory protein from Naja atra venom that targets the BK Ca channel146
Editorial [Hot topic: Metabolic syndrome in an Asian Chinese population and agents and targets for cardiovascular protection]20
Properties of otolith-related vestibular nuclear neurons in response to bidirectional off-vertical axis rotation of the rat110
Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase213
A Ca2+-linked increase in coupled cAMP synthesis and hydrolysis is an early event in cholinergic and β-adrenergic stimulation of parotid secretion137
Structural Analysis of the Recognition of the Negative Regulator NmrA and DNA by the Zinc Finger from the GATA-Type Transcription Factor AreA52
Involvement of the cystic fibrosis transmembrane conductance regulator in the acidosis-induced efflux of ATP from rat skeletal muscle191
Differential expressions and roles of hypoxia-inducible factor-1α, -2α and -3α in the rat carotid body during chronic and intermittent hypoxia98
Identification of ‘erasers’ for lysine crotonylated histone marks using a chemical proteomics approach174
Plasmodium falciparum Sir2A preferentially hydrolyzes medium and long chain fatty acyl lysine119
Crystal structure of the cysteine-rich secretory protein stecrisp reveals that the cysteine-rich domain has a K + channel inhibitor-like fold232
Inhibition by multivalent cations of contraction induced by Chinese cobra venom cardiotoxin in gunea pig papillary muscle51
Regulation of cholesterol biosynthesis in sham operated and regenerated rat liver32
Internal calcium stores and norepinephrine overflow from isolated, field stimulated rat vas deferens58
Structural basis for modulation of Kv4 K + channels by auxiliary KChIP subunits194
The crystal structure of cyclic ADP-ribose.50
Structural plasticity of dendritic spines: The underlying mechanisms and its dysregulation in brain disorders69
Subcellular localization of cyclic ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activities in porcine airway smooth muscle182
Inhibition of catechol-O-methyltransferase by gossypol: The effect of plasma proteins32
Neurokinin receptor 3 peptide exacerbates 6-hydroxydopamine-induced dopaminergic degeneration in rats through JNK pathway53
Phrenic response to hypercapnia in the unanesthetized, decerebrate, newborn rat50
Excitatory effect of histamine on rat spinal motoneurons by activation of both H 1 and H 2 receptors in vitro73
Impaired [Ca2+](i) and pH(i) responses to κ-opioid receptor stimulation in the heart of chronically hypoxic rats61
Characterization of ventilatory responses to hypoxia in neonatal rats192
Regulation of vascular tone: cross-talk between sarcoplasmic reticulum and plasmalemma159
Nasal airway response to mucosal perfusion and outflow resistance in the dog and rat59
Revealing CD38 Cellular Localization Using a Cell Permeable, Mechanism-Based Fluorescent Small-Molecule Probe62
Effect of environmental and hypothalamic factors on thyrotropin secretion in the hypothyroid rat47
Trimetazidine Therapy Prevents Obesity-Induced Cardiomyopathy in Mice58
Antitumor effects of a refined polysaccharide peptide fraction isolated from Coriolus versicolor: in vitro and in vivo studies98
Macromolecular envelope determination and envelope-based phasing152
Inositol triphosphate induces calcium release from nonmitochondrial stores in sea urchin egg homogenates51
Synthesis and calcium mobilization activity of cADPR analogues which integrate nucleobase, northern and southern ribose modifications51
Hyper-expression of human apolipoprotein E4 in astroglia and neurons does not enhance amyloid deposition in transgenic mice83
Constitutive cAMP response element binding protein (CREB) activation by Alzheimer's disease presenilin-driven inositol trisphosphate receptor (InsP 3R) Ca 2+ signaling69
Responses of cardiovascular neurons in the rostral ventrolateral medulla of the normotensive Wistar Kyoto and spontaneously hypertensive rats to iontophoretic application of angiotensin II51
Neuroendocrinology of melatonin in reproduction: Recent developments184
Analysis of surface structures of hydrogen bonding in protein-ligand interactions using the alpha shape model74
A revisitation on the mechanism of action of KCl-induced vascular smooth muscle contraction: a key role of cation binding to the plasma membrane118
Catalysis-associated conformational changes revealed by human CD38 complexed with a non-hydrolyzable substrate analog208
CD38/cADPR/Ca 2+ pathway promotes cell proliferation and delays nerve growth factor-induced differentiation in PC12 cells198
Phosphorylation By Casein Kinase 1 Regulates Tonicity-induced Osmotic Response Element-binding Protein/tonicity Enhancer-binding Protein Nucleocytoplasmic Trafficking125
Secretin as a neurohypophysial factor regulating body water homeostasis222
The Physiology and Pharmacology of the CFTR Cl- Channel108
Elevated endogenous nitric oxide increases Ca 2+ flux via L-type Ca 2+ channels by S-nitrosylation in rat hippocampal neurons during severe hypoxia and in vitro ischemia63
Chronic intermittent hypoxia alters Ca2+ handling in rat cardiomyocytes by augmented Na+/Ca2+ exchange and ryanodine receptor activities in ischemia-reperfusion197
Upregulation of a local renin-angiotensin system in the rat carotid body during chronic intermittent hypoxia49
The relationship between intracellular pH and adenosine output from red muscle fibres of the rat103
Melatonin slowed the early biochemical progression of hormone-refractory prostate cancer in a patient whose prostate tumor tissue expressed MT 1 receptor subtype64
Lean body mass of well-nourished women is preserved during lactation156
Large-scale purification of Aplysia ADP-ribosylcyclase and measurement of its activity by fluorimetric assay164
Bioassay for determining endogenous levels of cyclic ADP-ribose114
Engineering of the immune system for human ESC- and iPSC-derived grafts58
A novel method for measurement of intravesicular pH using fluorescent probes50
Neuronal activities underlying inspiratory termination by pneumotaxic mechanisms50
Estimating unobserved reflection intensities in Laue diffraction by the maximum-entropy method197
Possible role of adrenomedullin in the pathogenesis of tubal ectopic pregnancy196
Novel mechanism of intracellular calcium release in pituitary cells44
Relationship between muscarinic receptor reserve and mode of excitation-contraction coupling in bovine tracheal smooth muscle80
Effect of engineered anisotropy on the susceptibility of human pluripotent stem cell-derived ventricular cardiomyocytes to arrhythmias72
Roles and mechanisms of the CD38/cyclic adenosine diphosphate ribose/Ca2+ signaling pathway48
Coexpression of adrenomedullin and its receptors in the reproductive system of the rat: effects on steroid secretion in rat ovary137
Crystallization of ADP-ribosyl cyclase from Aplysia californica52
Characterization of interleukin-1β in Helicobacter pylori-induced gastric inflammation and DNA methylation in interleukin-1 receptor type 1 knockout (IL-1R1-/-) mice72
Sodium homeostasis in rat hippocampal slices during oxygen and glucose deprivation: Role of voltage-sensitive sodium channels44
Signal transduction of receptor-mediated antiproliferative action of melatonin on human prostate epithelial cells involves dual activation of Gα s and Gα q proteins134
Mechanism of chronic intermittent hypoxia-induced impairment in synaptic plasticity and neurocognitive dysfunction58
Gene expression of glutamate receptors GluR1 and NR1 is differentially modulated in striatal neurons in rats after 6-hydroxydopamine lesion141
The effect of lactic acid on intracellular pH and adenosine output from superfused rat soleus muscle fibres69
A conserved hydrophobic patch on Vβ domains revealed by TCRβ chain crystal structures: implications for pre-TCR dimerization148
Migration of bone marrow-derived mesenchymal stem cells induced by tumor necrosis factor-alpha and its possible role in wound healing33
Cardiac and vascular effects of nitric oxide synthase inhibition in lipopolysaccharide-treated rats159
Combining direct methods with isomorphous replacement or anomalous scattering data. VII. Ab initio phasing of one-wavelength anomalous scattering data from a small protein175
Differential expression of AMPA receptor subunits GluR1, 2, 3, and 4 in substance P receptor-containing neurons of the neostriatal regions of rats107
Roles of cADPR and NAADP in pancreatic cells165
Dichlorodiphenyltrichloroethane specifically depletes dopaminergic neurons in primary cell culture113
Collaborative regulation of development but independent control of metabolism by two epidermis-specific transcription factors in Caenorhabditis elegans96
Behavioral and neurochemical characterization of transgenic mice carrying the human presenilin-1 gene with or without the leucine-to-proline mutation at codon 235154
Solving crystal structures from two-wavelength X-ray powder diffraction data - Breaking the phase ambiguity in the noncentrosymmetric case181
A comparison of (125I)iodomelatonin binding sites in testes and brains of heavy meat-type Japanese quail with a randombred strain127
Characterization of alpha 2 adrenoceptors and other adrenoceptors in membranes isolated from dog mesenteric nerve axons92
Feasibility of one-shot-per-crystal structure determination using Laue diffraction142
Requirement of TGF-β Receptor-Dependent Activation of c-Jun N-Terminal Kinases (JNKs)/Stress-Activated Protein Kinases (Sapks) for TGF-β Up-Regulation of the Urokinase-Type Plasminogen Activator Receptor28
Acute hypoxia elevates nitric oxide generation in rat carotid body in vitro59
Nestin small interfering RNA (siRNA) reduces cell growth in cultured astrocytoma cells190
Beneficial mechanisms of aerobic exercise on hepatic lipid metabolism in non-alcoholic fatty liver disease143
Serum potassium and aldosterone levels in gossypol-treated rats69
The functional role of a conserved loop in EAL domain-based cyclic di-GMP-specific phosphodiesterase72
Spatiotemporal characteristics of central otolith neurons151
Food properties that influence neuromuscular activity during human mastication162
Melatonin implant decreases the density of 2[125I]iodomelatonin binding sites in the chicken spleen201
Remifentanil mimics cardioprotective effect of ischemic preconditioning via protein kinase C activation in open chest of rats206
Measurements of accurate x-ray scattering data of protein solutions using small stationary sample cells136
Lithium ion alters Ins(1,4,5)P3 production and mobilisation of intracellular free calcium in k-agonist stimulated rat ventricular myocytes98
Effects of reserpine treatment on arrhythmogenesis during ischaemia and reperfusion in the isolated rat heart42
Cloning and expression of a rat Smad1: Regulation by TGFβ and modulation by the Ras/MEK pathway27
Structural Characterization of H1N1 Nucleoprotein-Nucleozin Binding Sites127
Adrenergic mechanisms in canine nasal venous systems194
Effects of L-NAME on nasal venoconstriction induced by acetylcholine in anaesthetized dogs87
Effect of glucose, insulin, and potassium on contractile force in the hypoxic isolated perfused rat heart150
Structure, function and regulation of BP-3, a member of the CD38/ADP-ribosyl cyclase family90
Lactation increases prolactin receptor expression in spleen and thymus of rats71
Localization and characterization of 2[125I]iodomelatonin binding sites in female rat uterus27
A unified mechanism of enzymatic synthesis of two calcium messengers: Cyclic ADP-ribose and NAADP38
DeltaNp63 versatilely regulates a Broad NF-kappaB gene program and promotes squamous epithelial proliferation, migration, and inflammation57
Intracellular sodium in mammalian muscle fibers after eccentric contractions59
Porcine CD38 exhibits prominent secondary NAD+ cyclase activity54
Combining direct methods with isomorphous replacement or anomalous scattering data. VI. Incorporation of heavy-atom information into Hauptman's distributions169
Application of the modified vaccination technique for the prevention and cure of chronic ailments124
Phasing from an envelope87
Nitric oxide modulation of voltage-gated calcium current by S-nitrosylation and cGMP pathway in cultured rat hippocampal neurons108
Is single-wavelength anomalous scattering sufficient for solving phases? A comparison of different methods for a 2.1 Å structure solution138
Elevated spontaneous activity of phenylephrine-excited neurons in the caudal ventrolateal medulla of spontaneously hypertensive rats102
α-Lipoic acid increases cardiac glucose oxidation independent of AMP-activated protein kinase in isolated working rat hearts58
Melatonin attenuates rat carotid chemoreceptor response to hypercapnic acidosis178
Melatonin enhances the hypoxic response of rat carotid body chemoreceptor164
Projections from facial nucleus interneurons to the respiratory groups of brainstem in the rat42
Stimulation of glucose oxidation protects against acute myocardial infarction and reperfusion injury62
Activation of the mitogen-activated protein kinase pathway by transforming growth factor-beta.29
Developmental cues for the maturation of metabolic, electrophysiological and calcium handling properties of human pluripotent stem cell-derived cardiomyocytes49
Modulator and messenger functions of cyclic ADP-ribose in calcium signaling35
Biology of G protein-coupled melatonin receptors in the epididymis and prostate of mammals178
Chronic hypoxia upregulates the expression and function of proinflammatory cytokines in the rat carotid body250
Structural determinants of Trk receptor specificities using BDNF-based neurotrophin chimeras28
Ontogeny of 2-[ 125I]iodomelatonin binding sites in the chicken (Gallus domesticus) kidney and spleen92
Effects of PGE2 on circulation and secretion of submandibular gland in anaesthetized dogs113
A novel cycling assay for cellular cADP-ribose with nanomolar sensitivity145
Interaction of angiotensin II and rostral ventrolateral medullary cardiovascular neurons in the genesis of hypertension87
Chondroitin sulfates in the developing rat hindbrain confine commissural projections of vestibular nuclear neurons210
Fusion with stem cell makes the hepatocellular carcinoma cells similar to liver tumor-initiating cells86
The current status and challenges in computational analysis of genomic big data58
Increase of proenkepahlin mRNA and enkephalin content of rat striatum after daily injection of haloperidol for 2 to 3 weeks188
Cyclic GMP-dependent and -independent effects on the synthesis of the calcium messengers cyclic ADP-ribose and nicotinic acid adenine dinucleotide phosphate167
Analysis of Differentially Expressed Genes in Hepatocellular Carcinoma with Hepatitis C Virus by Suppression Subtractive Hybridization41
Adrenomedullin: Exciting new horizons152
Mechanisms of sympathetic enhancement and inhibition of parasympathetically induced salivary secretion in anaesthetized dogs69
Effect of testicular capsulotomy on secretion of testosterone and gonadotrophins in rats98
Transfection of rat brain cells by electroporation158
Energized gastric microsomal membrane vesicles. An index using metachromatic dyes50
Preconditioning with Porphyromonas gingivalis lipopolysaccharide may confer cardioprotection and improve recovery of the electrically induced intracellular calcium transient during ischemia and reperfusion208
The role of the autonomic nerves in the control of nasal circulation216
Modulation of human cardiac transient outward potassium current by EGFR tyrosine kinase and Src-family kinases121
The role of local renin-angiotensin system in arterial chemoreceptors in sleep-breathing disorders35
Characterization of functional ion channels in human cardiac c-kit+ progenitor cells59
Streptozotocin-induced diabetes has differential effects on atrial natriuretic peptide synthesis in the rat atrium and ventricle: A study by solution-hybridization-RNase protection assay181
Peroxisome proliferator –activated receptor gamma ameliorates pulmonary arterial hypertension by inhibiting 5-hydroxytryptamine 2B receptor31
Cyclic ADP-ribose and calcium signaling in eggs55
Acute inhibition of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel by thyroid hormones involves multiple mechanisms82
ADP-ribosyl cyclase: Crystal structures reveal a covalent intermediate159
Changes in prejunctional potency of B-HT 933 during aging in the rat vas deferens56
Age attenuation in the rat of pituitary-thyroid response to cold51
Purification, partial characterization, crystallization and structural determination of AHP-LAAO, a novel L-amino-acid oxidase with cell apoptosis-inducing activity from Agkistrodon halys pallas venom191
Adrenomedullin inhibits norepinephrine-induced contraction of rat seminal vesicle99
Adrenomedullin in rat follicles and corpora lutea: Expression, functions and interaction with endothelin-1277
Immunoactive TSH in the amniotic fluid of the rat52
Patterns of pineal melatonin secretion in rabbits: Diurnal variation of basal and pulsatile release70
Analysis of banana transcriptome and global gene expression profiles in banana roots in response to infection by race 1 and tropical race 4 of Fusarium oxysporum f. sp. cubense192
Revisit of the Cardiac Inward Rectifier Potassium Current IK1146
Remifentanil preconditioning confers cardioprotection via cardiac κ- and δ-opioid receptors163
Calcium Signaling by Cyclic ADP-Ribose and NAADP: A Decade of Exploration18
2-[125I]Iodomelatonin binding sites in the quail heart: Characteristics, distribution and modulation by guanine nucleotides and cations62
Cardiac tissue engineering using human stem cell-derived cardiomyocytes for disease modeling and drug discovery126
An anatomical investigation of the nasal venous vascular bed in the dog31
Audit of basal cell carcinoma in Princess Margaret Hospital, Hong Kong: Usefulness of frozen section examination in surgical treatment75
In vivo intracellular responses of the medial geniculate neurones to acoustic stimuli in anaesthetized guinea pigs170
Studies of melatonin effects on epithelia using the human embryonic kidney-293 (HEK-293) cell line179
Abscisic acid signaling through cyclic ADP-ribose in plants193
Regulation of nucleocytoplasmic trafficking of transcription factor OREBP/TonEBP/NFAT5175
Mapping nanostructure: A systematic enumeration of nanomaterials by assembling nanobuilding blocks at crystallographic positions144
Crystal structure of 3-hydroxyanthranilic acid 3,4-dioxygenase from Saccharomyces cerevisiae: A special subgroup of the type III extradiol dioxygenases185
Evidence for a direct action of melatonin on the immune system86
2[125I]iodomelatonin binding sites in guinea pig platelets187
Excitatory effect of histamine on neuronal activity of rat globus pallidus by activation of H2 receptors in vitro175
Preparation, crystallization and X-ray diffraction analysis to 1.5 Å resolution of rat cysteine dioxygenase, a mononuclear iron enzyme responsible for cysteine thiol oxidation178
The regeneration of transected sciatic nerves of adult rats using chitosan nerve conduits seeded with bone marrow stromal cell-derived Schwann cells216
SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine224
Malonyl-CoA mediates leptin hypothalamic control of feeding independent of inhibition of CPT-1a41
Binding characteristics, regional distribution and diurnal variation of [125I]-iodomelatonin binding sites in the chicken brain58
Effects of kainic acid administered to the caudal ventrolateral medulla on arterial blood pressure in the spontaneously hypertensive and normotensive Wistar-Kyoto rats41
Lycium barbarum polysaccharides protect mice liver from carbon tetrachloride-induced oxidative stress and necroinflammation210
Maturation of otolith-related brainstem neurons in the detection of vertical linear acceleration in rats139
Inhibition of malignant trophoblastic cell proliferation in vitro and in vivo by melatonin201
Interaction between isoproterenol and acetylcholine on contractile force and cyclic nucleotide levels in the isolated perfused rat heart92
ADP-ribosyl cyclase and CD38: Multi-functional enzymes in Ca+2 signaling129
Ca2+-induced Ca2+ release in sea urchin egg homogenates: Modulation by cyclic ADP-ribose49
A novel system for simultaneous monitoring of locomotor and sound activities in animals202
The endocardium - Its possible role in myocardial function31
Effect of 1-phenylephrine on rat papillary muscle: influence of ageing28
The voltage-sensitive Na+/H+ exchange in sea urchin spermatozoa flagellar membrane vesicles studied with an entrapped pH probe26
An Unusual Allosteric Mobility of the C-Terminal Helix of a High-Affinity αL Integrin I Domain Variant Bound to ICAM-564
Enzymatic synthesis and characterizations of cyclic GDP-ribose. A procedure for distinguishing enzymes with ADP-ribosyl cyclase activity93
The distribution and gene expression of adrenomedullin in the rat brain: Peptide/mRNA and precursor/active peptide relationships170
The regional distribution of thyrotropin releasing hormone, LEU-enkephalin, MET-enkephalin, substance P, somatostatin and cholecystokinin in the rat brain and pituitary59
Identification and characterization of splice variants of ephrin-A3 and ephrin-A580
Functional expression of angiotensin II receptors in type-I cells of the rat carotid body207
Effects of Adrenomedullin on Tumour Necrosis Factor Alpha, Interleukins, Endothelin-1, Leptin, and Adiponectin in the Epididymal Fat and Soleus Muscle of the Rat61
Regulation of the angiotensin-converting enzyme activity by a time-course hypoxia in the carotid body155
Aldose Reductase Protects Against Early Atherosclerotic Lesion Formation In Apolipoprotein E-null Mice145
Hypothyroidism and pituitary contents of immunoactive met-enkephalin and β-endorphin in male rats of different ages39
Modified vaccination technique for prophylactic and therapeutic applications to combat endogenous antigen-induced disorders181
Efficacy of muscarinic stimulation and mode of excitation-contraction coupling in bovine trachealis muscle64
The influence of chronic hypoxia on the functional response to endothelin of the pulmonary artery from adult rats93
Accurate and highly complete synchrotron protein crystal Laue diffraction data using the ESRF CCD and the Daresbury Laue software225
Multiscale characterization of chronobiological signals based on the discrete wavelet transform130
Age-related differences in response regulation as revealed by functional MRI205
Disruption of MEF2C signaling and loss of sarcomeric and mitochondrial integrity in cancer-induced skeletal muscle wasting67
Melatonin ameliorates endothelial dysfunction, vascular inflammation, and systemic hypertension in rats with chronic intermittent hypoxia80
Structure of human upstream binding factor HMG box 5 and site for binding of the cell-cycle regulatory factor TAF1212
Selective over-expression of endothelin-1 in endothelial cells exacerbates inner retinal edema and neuronal death in ischemic retina110
Probing excitation-contraction coupling in trachealis smooth muscle with the mycotoxin cyclopiazonic acid125
Cardiovascular responses to electrical stimulation of the ventrolateral medulla of the spontaneously hypertensive rat89
The effect of haloperidol on met-enkaphalin, beta-endorphin, cholecystokinin and substance P in the pituitary, the hypothalamus and the striatum of rats during aging36
Endothelial nitric oxide synthase is a critical factor in experimental liver fibrosis171


TotJulAugSepOctNovDecJanFebMarAprMayJun
2017/201812718102910346581326936203532256318669721189788
2018/201924826173353564231617742248140819251269354458413591
2019/202017722337420155311505965163816942463708874991964
2020/2021500551151916798357714187399176575264175436174531362
2021/202215210212414852707595323429073634161309395107
2022/20234852961890000000000
Ever121016