ResearcherPage View Count

Geo Map
AS - Asia4888
EU - Europe3438
NA - North America2911
AF - Africa769
OC - Oceania281
HKU - The University of Hong Kong260
SA - South America10
UND - Undefined49
US - United States2896
CN - China2400
GB - United Kingdom1202
SG - Singapore1138
IE - Ireland1011
KR - Republic of Korea780
ZA - South Africa605
NL - Netherlands484
HK - Hong Kong480
FR - France442
OTH - Others1168
The University of Hong Kong260
Similarities and differences in apoptosis induced by staurosporine and wortmannin101
Interferon-γ increases intracellular calcium and inositol phosphates in primary human thyroid cell culture156
Adiponectin haploinsufficiency promotes mammary tumor development in MMTV-PyVT mice by modulation of phosphatase and tensin homolog activities214
The Kappa-opioid receptor specific agonist U50488H induces mitochondrial stress in cultured human cancer cells158
Reactive oxygen species (ROS) regulates the expression of the growth-arrest and DNA damage inducible gene-153 at the post-transcriptional level95
N-(4-hydrxophenyl)retinamide induces up-regulation of GADD153 in a nasopharyngeal carcinoma cell line139
Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation57
An Investigation of the Mutual Relationship between ER Stress and Oxidative Stress103
Evidence for direct and specific physical interaction between the stress-inducible CHOP mRNA and intracellular proteins100
EM23, a natural sesquiterpene lactone, targets thioredoxin reductase to activate JNK and cell death pathways in human cervical cancer cells166
Design, Development and Evaluation of Biochemistry Virtual Laboratory for Blended Learning158
The identification of sequence elements that mediate stabilization of the CHOP/Gadd153 mRNA by N-(4-hydroxyphenyl)retinamide (4HPR/fenretinide)101
The expression of P21/WAF1/CIP1 is not sufficient to mediate the anti-apoptotic action of Epidermal-Growth-Factor Receptor75
Lithium ion alters Ins (1,4,5) P3 production and mobilisation of intracellular free calcium in K-agoinst stimulated rat ventricular myocytes119
Virtually there: a journey to the HKU Medicine Island for teaching and learning45
Lithium ion alters Ins(1,4,5)P3 production and mobilisation of intracellular free calcium in k-agonist stimulated rat ventricular myocytes96
Further study on the mechanism responsible for inhibition of cAMP production in CNE-2 and H9c2 cells upon k-opioid receptor stimulation80
The role of reactive oxygen species in UPR-mediated cell death94
k-opioid receptor agonist inhibits the cholera toxin sensitive G-protein in the heart185
The antiproliferative effect of the kappa-specific opioid receptor agonist U50,488H does not correlate with the suppression of cyclic AMP and mobilisation of intracellular calcium126
The enzyme activity of a membrane-bound isoform of thioredoxin reductase is inhibited by adenine mononucleotide149
Upregulation of GADD153 expression in the apoptotic signaling of N-(4-hydroxyphenyl)retinamide (4HPR)97
The up-regulation of GADD153 expression in human epithelial tumor cells treated with N-(4-hydroxyphenyl)retinamide (4HPR)93
Virtually there: a journey to the HKU Medicine Island for teaching and learning39
ProteoMirExpress: inferring microRNA-centered regulatory networks from high-throughput proteomic and transcriptome data69
Stimulation of k-receptor in cultured heart myoblasts suppresses intracellular cAMP level and elevates intracellular Ca2+ through a pertussis-toxin-sensitive mechanism83
The potential role of Simian Virus 40 polyA sequence (SV40 polyA) to mediate stress-inducible mRNA translation98
κ-opioid receptor agonist inhibits the cholera toxin-sensitive G protein in the heart124
Latent membrane protein 1 interacts with the proliferation and apoptotic pathways in epithelial cells107
Reactive oxygen species (ROS) regulates the expression of the growth-arrest-and DNA-damage inducible gene at the post-transcriptional level93
Stimulation of the k-receptor in cultured cardiomyoblast produced different combinations of intracellular signals at low and high concentrations of specific k-agonists86
O-032. the relationship of p85 and the apoptotic signaling of N-(4-hydroxyphenyl)retinamide (4HPR)166
Reduction of Placental Thioredoxin Expression in Diabetic Pregnancies104
Identification of plasmin as the major contaminant in immunoglobulin preparations161
The Over-expression of Bcl-2 antagonizes the pro-apoptotic function of the Kappa-Opioid receptor129
The identification of enzyme activities that catalyse the reduction of immuoglobulin G interchain disulphides117
Functional significance of the 3’-UTR in the mRNA of the stress-inducible protein CHOP/Gadd15385
Studies of kappa opioid receptor in mediating stress response via the phospholipid C pathway80
Epidermal growth factor induced differential calcium signaling patterns in epidermoid cell lines121
The upregulation of GADD153 expression and N-(4-hydroxyphenyl)retinamide (4HPR)-induced apoptosis87
Erratum: PKCδ-dependent deubiquitination and stabilization of Gadd45 in A431 cells overexposed to EGF (Biochemical and Biophysical Research Communication (2001) 285:2 (283-288))127
Methylation and expression of human pepsinogen genes in normal tissues and their alteration in stomach cancer154
Regulation of GADD153 Expression at Post-transcriptional Level by ROS104
PKC(delta)-dependent de-ubiquination and stabilisation of Gadd45 in A431 cells over-exposed to EGF140
In vivo activation and nuclear translocation of phosphorylated glycogen synthase kinase-3β in neuronal apoptosis: Links to tau phosphorylation182
The role of the AU-rich element in the mRNA of the stress-inducible protein CHOP/Gadd153105
Establishment and characterization of a new xenograft-derived human esophageal squamous cell carcinoma cell line SLMT-1 of Chinese origin225
Specific inhibition of protein disulphide reductase activity of a 60kda rat liver protein by adenine nucleotides106
The use of cells doubly labelled with [ 14C]inositol and [ 3H]inositol to search for a hormone-sensitive inositol lipid pool with atypically rapid metabolic turnover137
B5, a thioredoxin reductase inhibitor, induces apoptosis in human cervical cancer cells by suppressing the thioredoxin system, disrupting mitochondrion-dependent pathways and triggering autophagy92
Demonstration of the presence of plasminogen activator in human small intestine164
Communication in medical education: harnessing the power of the Internet90
Pertussis toxin, but not tyrosine kinase inhibitors, abolishes effects of U-50488H on [Ca2+](i) in myocytes112
A study of tissue plasminogen activator forms from human small intestine131
The p21/WAF1/Cip1 mediates the anti-mitogenic but not the anti-apoptotic action of epidermal growth factor (EGF) in an epithelial tumor cell line140
The Overexpression of Bcl-2 Antagonizes the Proapoptotic Function of the Kappa-Opioid Receptor143
Epidermal-growth factor is not a mitogen for the nasopharyngeal carcinoma-derived cell line, CNE-2103
Isolation and characterization of an abortifacient protein, momorcochin, from root tubers of Momordica cochinchinensis (family cucurbitaceae).167
A characterisation of the cellular toxicity induced by manganese137
Epidermal growth factor induces Gadd45 (growth arrest and DNA damage inducible protein) expression in A431 cells200
Concept testing is used as an assessment method to evaluate effectiveness of instructional strategies58
Further evidence that the 3’Untranslated Region of the CHOP mRNA possesses mRNA destabilizing effect29
Activation of epidermal-growth factor receptor leads to growth inhibition and phosphorylation of the SHC-protein in a human nasopharyngeal cell line118
Synergistically interferon-g enhances paclitaxel-induced nitric oxide production in a murine alveolar macrophage cell line: roles of NF-kB, MEK and PKCd96
Development of a Prototype Biochemistry Virtual Laboratory: reflections on the Instructional Design135
κ-Opioid receptor potentiates apoptosis via a phospholipase C pathway in the CNE2 human epithelial tumor cell line164
Inositol lipids in cardiomyocytes: relationship to k-agonist signal transduction126
Functional significance of the 3'-UTR in the mRNA of the stress-inducible protein CHOP/Gadd153101
Implementation of an interprofessional team-based learning program involving seven undergraduate health and social care programs from two universities, and students' evaluation of their readiness for interprofessional learning189
A characterization of the in vitro effects of metal ions on thioredoxin reductase188
Reactive oxygen species stimulate phosphorylation of eIF2α independent of protein folding in ER-stressed cells87
Activation of translocation of CDC2 in dexamethasone-induced apoptotic human nasopharyngeal carcinoma CNE3 cells94
Kappa-opioid receptor potentiates apoptosis via a phospholipase-C pathway in the CNE2 human epithelial tumor cell line110
The induction of p21/WAF1/CIP1 expression by the specific kappa opioid receptor agonist is independent of MAPK and PKC81
Characteristics of phosphatidylinositol headgroup exchange in rat heart membranes107
A proposed model for UPR-mediated cellular survival and cell death102
The activity of N-(4-hydroxyphenyl) retinamide in nasopharyngeal carcinoma cells123
Implications of Virtual Lab Design and Development92
Lithium attenuates the effects of dynorphin A(1-13) on inositol 1,4,5-trisphosphate and intracellular Ca2+ in rat ventricular myocytes149
Expression of a kallikrein-like protein in prostatic intraepithelial neoplasia in ventral prostate of the noble rat188
The biological effect of fenretinide in nasopharyngeal carcinoma cells112
Interferon-genhances nitric oxide synthase expression induced by paclitaxel in alveolar macrophages: the roles of ras/mek/erk and NF-kB in signal transduction146
Overexpression of a kallikrein-like protein in ventral prostate secretion at early stage of carcinogenesis in the Noble rat103
Improving undergraduate learning experience of biochemical techniques by the flipped class approach100
Evidence for physical interaction between CHOP/Gadd153 mRNA and specific intracellular proteins92
The effect of pollutant-induced cellular stress on mRNA stability19
The epstein-Barr virus encoded latent membrane protein-1 protects cells against caspase-independent apoptosis90
Signal transduction in the cardiac k-receptor167
Impaired G(s)α and adenylyl cyclase cause β-adrenoceptor desensitization in chronically hypoxic rat hearts134
Expression of a kallikrein-like protein in prostatic intraepithelial neoplasia in ventral prostate of the Noble rat112
ROS mediates 4HPR-induced posttranscriptional expression of the Gadd153 gene182
The biochemical mechanism of hypoxia-induced mobilization of glycogen in cultured cancer cell73
Intracellular Reactive Oxygen Species enhances the survival of cells under the conditions of ER stress80
Meeting report: Second Singapore Biologics Manufacturing Conference131
Specific inhibition of protein disulphide reductase activity of a 60kda rat liver protein by adenine nucleotides78
Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation44
Defining the effects of hypoxia on glycogen metabolism in cancer cells30
Inositol 1:2(cyclic),4,5-trisphosphate is not a major product of inositol phospholipid metabolism in vasopressin-stimulated WRK1 cells.113
The Identification of Regulatory Element(s) in the Promoter of the Thioredoxin Reductase gene100
The enzymatic mechanism mediating the breakdown of glycogen in hypoxic tumor cells17
The expression of p21/WAF1/CIP1 is not sufficient to mediate the anti-apoptotic action of Epidermal-Growth-Factor Receptor78
N-methyl-D-Aspartate receptor blockade-mediated apoptosis induced GSK activation and increase of TAU phosphorylation in newborn rats139
The relationship of p85 and the apoptotic signalling of N-(4-hydroxyphenyl)retinamide (4HPR)82
Phosphatidylinositol 3-kinase and protein kinase C are required for the inhibition of caspase activity by epidermal growth factor166
Designing formative assessment for medium class-size teaching in an undergraduate biochemistry program49
ProteoMirExpress: inferring microRNA and protein-centered regulatory networks from high-throughput proteomic and mRNA expression data75
The PERK/eIF2α signaling pathway of Unfolded Protein Response is essential for N-(4-hydroxyphenyl)retinamide (4HPR)-induced cytotoxicity in cancer cells185
Functional significance of the AU-rich sequence element in the mRNA of the stress- inducible protein CHOP/Gadd15394
Effect of lithium and myo-inositol on the time courses of changes in inositol trisphosphate and free calcium concentrations in K opioid agonist-stimulated rat ventricular myocytes (Abstract)93
Inositol phosphates: the elucidation of forms and functions91
Blended assessment strategies for Blended Teaching and Learning79