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- Publisher Website: 10.1002/hon.885
- Scopus: eid_2-s2.0-66949156552
- PMID: 19248048
- WOS: WOS:000267352100006
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Article: Determinants of peripheral blood count value in long-term survivors of allogeneic hemopoietic stem cell transplantation
Title | Determinants of peripheral blood count value in long-term survivors of allogeneic hemopoietic stem cell transplantation |
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Authors | |
Keywords | CBP HSCT Long-term survivors |
Issue Date | 2009 |
Publisher | John Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/3182 |
Citation | Hematological Oncology, 2009, v. 27 n. 2, p. 98-101 How to Cite? |
Abstract | Hemopoeitic stem cell transplant (HSCT) recipients are monitored by regular complete blood picture (CBP). The reference ranges for acceptable values are undefined. We analysed the CBP in 228 stable HSCT survivors (median follow-up 103 months, range 60-212) without transplant-related medications and complications. Compared with donors, recipients had lower absolute neutrophil count (ANC) and platelet levels (Plt) and higher mean corpuscular volume (MCV), but comparable hemoglobin (Hb) and absolute lymphocyte count (ALC). There was significant donor-recipient correlation in all CBP parameters (Hb, ALC, ANC, MCV, Plt). Significant correlation was also found between levels of Hb, white cell and Plt among recipients. All counts were higher in patients with longer follow-up. Donor and recipient gender, age and underlying diagnosis can influence stable CBP values.We conclude that both host and marrow factors influence CBP values in stably engrafted recipients. 'Abnormal' CBP values deviating from that in normal populations may not have clinical significance. Copyright © 2009 John Wiley & Sons, Ltd. |
Persistent Identifier | http://hdl.handle.net/10722/125002 |
ISSN | 2023 Impact Factor: 3.3 2023 SCImago Journal Rankings: 0.820 |
ISI Accession Number ID | |
References |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Paul, KA | en_HK |
dc.contributor.author | Lie, AKW | en_HK |
dc.contributor.author | Liang, R | en_HK |
dc.contributor.author | Au, WY | en_HK |
dc.date.accessioned | 2010-10-31T11:06:01Z | - |
dc.date.available | 2010-10-31T11:06:01Z | - |
dc.date.issued | 2009 | en_HK |
dc.identifier.citation | Hematological Oncology, 2009, v. 27 n. 2, p. 98-101 | en_HK |
dc.identifier.issn | 0278-0232 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/125002 | - |
dc.description.abstract | Hemopoeitic stem cell transplant (HSCT) recipients are monitored by regular complete blood picture (CBP). The reference ranges for acceptable values are undefined. We analysed the CBP in 228 stable HSCT survivors (median follow-up 103 months, range 60-212) without transplant-related medications and complications. Compared with donors, recipients had lower absolute neutrophil count (ANC) and platelet levels (Plt) and higher mean corpuscular volume (MCV), but comparable hemoglobin (Hb) and absolute lymphocyte count (ALC). There was significant donor-recipient correlation in all CBP parameters (Hb, ALC, ANC, MCV, Plt). Significant correlation was also found between levels of Hb, white cell and Plt among recipients. All counts were higher in patients with longer follow-up. Donor and recipient gender, age and underlying diagnosis can influence stable CBP values.We conclude that both host and marrow factors influence CBP values in stably engrafted recipients. 'Abnormal' CBP values deviating from that in normal populations may not have clinical significance. Copyright © 2009 John Wiley & Sons, Ltd. | en_HK |
dc.language | eng | en_HK |
dc.publisher | John Wiley & Sons Ltd. The Journal's web site is located at http://www3.interscience.wiley.com/cgi-bin/jhome/3182 | en_HK |
dc.relation.ispartof | Hematological Oncology | en_HK |
dc.subject | CBP | - |
dc.subject | HSCT | - |
dc.subject | Long-term survivors | - |
dc.subject.mesh | Adolescent | en_HK |
dc.subject.mesh | Adult | en_HK |
dc.subject.mesh | Anemia, Aplastic - blood - surgery | en_HK |
dc.subject.mesh | Blood Cell Count | en_HK |
dc.subject.mesh | Female | en_HK |
dc.subject.mesh | Follow-Up Studies | en_HK |
dc.subject.mesh | Graft Survival | en_HK |
dc.subject.mesh | Hematopoietic Stem Cell Transplantation - statistics & numerical data | en_HK |
dc.subject.mesh | Hemoglobins - analysis | en_HK |
dc.subject.mesh | Humans | en_HK |
dc.subject.mesh | Leukemia - blood - surgery | en_HK |
dc.subject.mesh | Lymphoma - blood - surgery | en_HK |
dc.subject.mesh | Male | en_HK |
dc.subject.mesh | Middle Aged | en_HK |
dc.subject.mesh | Survivors | en_HK |
dc.subject.mesh | Transplantation, Homologous | en_HK |
dc.subject.mesh | Young Adult | en_HK |
dc.title | Determinants of peripheral blood count value in long-term survivors of allogeneic hemopoietic stem cell transplantation | en_HK |
dc.type | Article | en_HK |
dc.identifier.openurl | http://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0278-0232&volume=27&issue=2&spage=98–101&epage=&date=2009&atitle=Determinants+of+peripheral+blood+count+value+in+long-term+survivors+of+allogeneic+hemopoietic+stem+cell+transplantation | en_HK |
dc.identifier.email | Liang, R:rliang@hku.hk | en_HK |
dc.identifier.authority | Liang, R=rp00345 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1002/hon.885 | en_HK |
dc.identifier.pmid | 19248048 | - |
dc.identifier.scopus | eid_2-s2.0-66949156552 | en_HK |
dc.identifier.hkuros | 180720 | en_HK |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-66949156552&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 27 | en_HK |
dc.identifier.issue | 2 | en_HK |
dc.identifier.spage | 98 | en_HK |
dc.identifier.epage | 101 | en_HK |
dc.identifier.isi | WOS:000267352100006 | - |
dc.publisher.place | United Kingdom | en_HK |
dc.identifier.scopusauthorid | Paul, KA=26667228600 | en_HK |
dc.identifier.scopusauthorid | Lie, AKW=24284842400 | en_HK |
dc.identifier.scopusauthorid | Liang, R=26643224900 | en_HK |
dc.identifier.scopusauthorid | Au, WY=7202383089 | en_HK |
dc.identifier.issnl | 0278-0232 | - |