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- Publisher Website: 10.1016/0016-6480(85)90367-3
- Scopus: eid_2-s2.0-0021839861
- PMID: 4018557
- WOS: WOS:A1985AMH7100001
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Article: The in vitro metabolism of radioactive progesterone and testosterone by the gonads of the protandrous Rhabdosargus sarba at various sexual phases
Title | The in vitro metabolism of radioactive progesterone and testosterone by the gonads of the protandrous Rhabdosargus sarba at various sexual phases |
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Authors | |
Issue Date | 1985 |
Publisher | Academic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygcen |
Citation | General And Comparative Endocrinology, 1985, v. 59 n. 2, p. 171-183 How to Cite? |
Abstract | The in vitro steroidogenic capacity of the gonadal tissue in the protandrous Rhabdosargus sarba was studied. Testicular and ovarian tissues from various sexual phases were used either separately or combined. With progesterone as precursor, high yield of 5β-reduced metabolites, and no 11-ketotestosterone or 11β-hydroxytestosterone were found. The production of 5β-pregnan-3α-ol-20-one and 5β-pregnane-3,20-dione was very high in incubations with testicular tissue from intersexes or males and was low in those with ovarian tissue only. The production of 17α-hydroxyprogesterone was high in the female but was low in other sexual phases. With testosterone as precursor, 11-ketotestosterone and 11β-hydroxytestosterone were identified. The latter was the most abundant and prominent polar steroid in all incubations. 5β-Reductase activity was high in the male and relatively low in the female. 5α-Reduced products, however, were absent. There was an increase in the production of androstenedione as the animal underwent sex reversal. The significance of this change in steroidogenesis in this protandrous fish is at present under investigation. Experimental results also indicated that in the intersexual gonad there may be interaction between the testicular component and the ovarian component in steroidgenesis. |
Persistent Identifier | http://hdl.handle.net/10722/173087 |
ISSN | 2023 Impact Factor: 2.1 2023 SCImago Journal Rankings: 0.616 |
ISI Accession Number ID |
DC Field | Value | Language |
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dc.contributor.author | Yeung, WSB | en_US |
dc.contributor.author | Chan, STH | en_US |
dc.date.accessioned | 2012-10-30T06:27:53Z | - |
dc.date.available | 2012-10-30T06:27:53Z | - |
dc.date.issued | 1985 | en_US |
dc.identifier.citation | General And Comparative Endocrinology, 1985, v. 59 n. 2, p. 171-183 | en_US |
dc.identifier.issn | 0016-6480 | en_US |
dc.identifier.uri | http://hdl.handle.net/10722/173087 | - |
dc.description.abstract | The in vitro steroidogenic capacity of the gonadal tissue in the protandrous Rhabdosargus sarba was studied. Testicular and ovarian tissues from various sexual phases were used either separately or combined. With progesterone as precursor, high yield of 5β-reduced metabolites, and no 11-ketotestosterone or 11β-hydroxytestosterone were found. The production of 5β-pregnan-3α-ol-20-one and 5β-pregnane-3,20-dione was very high in incubations with testicular tissue from intersexes or males and was low in those with ovarian tissue only. The production of 17α-hydroxyprogesterone was high in the female but was low in other sexual phases. With testosterone as precursor, 11-ketotestosterone and 11β-hydroxytestosterone were identified. The latter was the most abundant and prominent polar steroid in all incubations. 5β-Reductase activity was high in the male and relatively low in the female. 5α-Reduced products, however, were absent. There was an increase in the production of androstenedione as the animal underwent sex reversal. The significance of this change in steroidogenesis in this protandrous fish is at present under investigation. Experimental results also indicated that in the intersexual gonad there may be interaction between the testicular component and the ovarian component in steroidgenesis. | en_US |
dc.language | eng | en_US |
dc.publisher | Academic Press. The Journal's web site is located at http://www.elsevier.com/locate/ygcen | en_US |
dc.relation.ispartof | General and Comparative Endocrinology | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Carbon Radioisotopes | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Fishes - Growth & Development | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Oocytes - Metabolism | en_US |
dc.subject.mesh | Ovary - Growth & Development - Metabolism | en_US |
dc.subject.mesh | Progesterone - Metabolism | en_US |
dc.subject.mesh | Sex Factors | en_US |
dc.subject.mesh | Sexual Maturation | en_US |
dc.subject.mesh | Steroids - Biosynthesis | en_US |
dc.subject.mesh | Testis - Growth & Development - Metabolism | en_US |
dc.subject.mesh | Testosterone - Metabolism | en_US |
dc.title | The in vitro metabolism of radioactive progesterone and testosterone by the gonads of the protandrous Rhabdosargus sarba at various sexual phases | en_US |
dc.type | Article | en_US |
dc.identifier.email | Yeung, WSB:wsbyeung@hkucc.hku.hk | en_US |
dc.identifier.authority | Yeung, WSB=rp00331 | en_US |
dc.description.nature | link_to_subscribed_fulltext | en_US |
dc.identifier.doi | 10.1016/0016-6480(85)90367-3 | - |
dc.identifier.pmid | 4018557 | - |
dc.identifier.scopus | eid_2-s2.0-0021839861 | en_US |
dc.identifier.volume | 59 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.spage | 171 | en_US |
dc.identifier.epage | 183 | en_US |
dc.identifier.isi | WOS:A1985AMH7100001 | - |
dc.publisher.place | United States | en_US |
dc.identifier.scopusauthorid | Yeung, WSB=7102370745 | en_US |
dc.identifier.scopusauthorid | Chan, STH=24368283200 | en_US |
dc.identifier.issnl | 0016-6480 | - |