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Conference Paper: A girl with atypical chronic inflammatory demyelinating polyneuropathy
Title | A girl with atypical chronic inflammatory demyelinating polyneuropathy |
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Authors | |
Keywords | Chronic Inflammatory Demyelinating Polyneuropathy Fibromyalgia |
Issue Date | 2010 |
Citation | XI International Child Neurology Congress, Cairo, Egypt, 2-7 May 2010. In International Journal of Child Neuropsychiatry, v. 7, Suppl., p. 90 How to Cite? |
Abstract | Purpose: Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a chronic,
acquired immune and inflammatory disorder that targets the peripheral nerves,
with a progressive or a relapsing-remitting course, presenting with predominant
weakness. Though pain is not a typical presentation in CIDP, it has been shown
that fibromyalgia patient can have CIDP and respond well to IVIG. Our patient
demonstrates a close relationship between CIDP and fibromyalgia.
Methods: Case report: A 17 year old girl was admitted with increase falling and
progressive difficulty in raising arms for six months. The weakness had a waxing
and waning course. Five months after onset of symptoms, she noticed shoulder
pain, tiredness and diurnal variation of weakness with severe weakness in the
morning. Examination showed multiple sites of tenderness, stiffness and
fatiguibility. She was initially suspected to have fibromyalgia with a slightly
elevated ESR and anti-dsDNA. Subsequent nerve conduction study confirmed
acquired demyelinating sensorimotor polyneuropathy with sural sparing. Lumbar
puncture showed protein-cytological dissociation. MRI spine demonstrated
gadolinium contrast enhancement of nerve roots at the cauda equina.
Result: CIDP was diagnosed and she was started on intravenous immunoglobulin
with rapid clinical improvement.
Conclusion: The presence of shoulder and neck pain, multiple sites of tenderness
and chronic fatigue symptom in our patient lead to the initial diagnosis of
fibromyalgia. The predominant fibromyalgia-like presentation of our patient
highlighting that neuropathic nature of pain and morning stiffness can be the
atypical presentation of CIDP at some stage. |
Description | Demyelinating diseases and Leukodystrophies Abstract Po- Demy/LK 7 |
Persistent Identifier | http://hdl.handle.net/10722/198797 |
ISSN |
DC Field | Value | Language |
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dc.contributor.author | Chan, SHS | - |
dc.contributor.author | Mak, W | - |
dc.contributor.author | Wong, VCN | - |
dc.date.accessioned | 2014-07-10T02:54:11Z | - |
dc.date.available | 2014-07-10T02:54:11Z | - |
dc.date.issued | 2010 | - |
dc.identifier.citation | XI International Child Neurology Congress, Cairo, Egypt, 2-7 May 2010. In International Journal of Child Neuropsychiatry, v. 7, Suppl., p. 90 | - |
dc.identifier.issn | 1687-3874 | - |
dc.identifier.uri | http://hdl.handle.net/10722/198797 | - |
dc.description | Demyelinating diseases and Leukodystrophies | - |
dc.description | Abstract Po- Demy/LK 7 | - |
dc.description.abstract | Purpose: Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is a chronic, acquired immune and inflammatory disorder that targets the peripheral nerves, with a progressive or a relapsing-remitting course, presenting with predominant weakness. Though pain is not a typical presentation in CIDP, it has been shown that fibromyalgia patient can have CIDP and respond well to IVIG. Our patient demonstrates a close relationship between CIDP and fibromyalgia. Methods: Case report: A 17 year old girl was admitted with increase falling and progressive difficulty in raising arms for six months. The weakness had a waxing and waning course. Five months after onset of symptoms, she noticed shoulder pain, tiredness and diurnal variation of weakness with severe weakness in the morning. Examination showed multiple sites of tenderness, stiffness and fatiguibility. She was initially suspected to have fibromyalgia with a slightly elevated ESR and anti-dsDNA. Subsequent nerve conduction study confirmed acquired demyelinating sensorimotor polyneuropathy with sural sparing. Lumbar puncture showed protein-cytological dissociation. MRI spine demonstrated gadolinium contrast enhancement of nerve roots at the cauda equina. Result: CIDP was diagnosed and she was started on intravenous immunoglobulin with rapid clinical improvement. Conclusion: The presence of shoulder and neck pain, multiple sites of tenderness and chronic fatigue symptom in our patient lead to the initial diagnosis of fibromyalgia. The predominant fibromyalgia-like presentation of our patient highlighting that neuropathic nature of pain and morning stiffness can be the atypical presentation of CIDP at some stage. | - |
dc.language | eng | - |
dc.relation.ispartof | International Journal of Child Neuropsychiatry. | - |
dc.subject | Chronic Inflammatory Demyelinating Polyneuropathy | - |
dc.subject | Fibromyalgia | - |
dc.title | A girl with atypical chronic inflammatory demyelinating polyneuropathy | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Chan, SHS: sophehs@HKUCC-COM.hku.hk | - |
dc.identifier.email | Wong, VCN: vcnwong@hku.hk | - |
dc.identifier.hkuros | 170398 | - |
dc.identifier.volume | 7 | - |
dc.identifier.issue | Suppl. | - |
dc.identifier.spage | 90 | - |
dc.identifier.epage | 90 | - |
dc.publisher.place | Egypt | - |
dc.customcontrol.immutable | yiu 140710 | - |
dc.identifier.issnl | 1687-3874 | - |