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Showing results 1 to 6 of 6

	Title	Author(s)	Issue Date	Views
	Design and optimization of (3-aryl-1H-indazol-6-yl)spiro[cyclopropane-1,3′-indolin]-2′-ones as potent PLK4 inhibitors with oral antitumor efficacy Journal:Bioorganic and Medicinal Chemistry Letters	Li, Sze Wan Liu, Yong Sampson, Peter B.Patel, Narendra Kumar Forrest, Bryan T.Edwards, Louise Laufer, Radoslaw Feher, Miklos Ban, Fuqiang Awrey, Donald E.Hodgson, Richard Beletskaya, Irina Mao, Guodong Mason, Jacqueline M.Wei, Xin Luo, Xunyi Kiarash, Reza Green, Erin Mak, Tak W.Pan, Guohua Pauls, Henry W.	2016	3
	Discovery of inhibitors of the mitotic kinase TTK based on N-(3-(3-sulfamoylphenyl)-1H-indazol-5-yl)-acetamides and carboxamides Journal:Bioorganic and Medicinal Chemistry	Laufer, Radoslaw Ng, Grace Liu, Yong Patel, Narendra Kumar B.Edwards, Louise G.Lang, Yunhui Li, Sze Wan Feher, Miklos Awrey, Don E.Leung, Genie Beletskaya, Irina Plotnikova, Olga Mason, Jacqueline M.Hodgson, Richard Wei, Xin Mao, Guodong Luo, Xunyi Huang, Ping Green, Erin Kiarash, Reza Lin, Dan Chi Chia Harris-Brandts, Marees Ban, Fuqiang Nadeem, Vincent Mak, Tak W.Pan, Guohua J.Qiu, Wei Chirgadze, Nickolay Y.Pauls, Henry W.	2014	9
	The discovery of orally bioavailable tyrosine threonine kinase (TTK) inhibitors: 3-(4-(heterocyclyl)phenyl)-1H-indazole-5-carboxamides as anticancer agents Journal:Journal of Medicinal Chemistry	Liu, Yong Lang, Yunhui Patel, Narendra Kumar Ng, Grace Laufer, Radoslaw Li, Sze Wan Edwards, Louise Forrest, Bryan Sampson, Peter B.Feher, Miklos Ban, Fuqiang Awrey, Donald E.Beletskaya, Irina Mao, Guodong Hodgson, Richard Plotnikova, Olga Qiu, Wei Chirgadze, Nickolay Y.Mason, Jacqueline M.Wei, Xin Lin, Dan Chi Chia Che, Yi Kiarash, Reza Madeira, Brian Fletcher, Graham C.Mak, Tak W.Bray, Mark R.Pauls, Henry W.	2015	8
	The discovery of PLK4 inhibitors: (E)-3-((1H-indazol-6-yl)methylene) indolin-2-ones as novel antiproliferative agents Journal:Journal of Medicinal Chemistry	Laufer, Radoslaw Forrest, Bryan Li, Sze Wan Liu, Yong Sampson, Peter Edwards, Louise Lang, Yunhui Awrey, Donald E.Mao, Guodong Plotnikova, Olga Leung, Genie Hodgson, Richard Beletskaya, Irina Mason, Jacqueline M.Luo, Xunyi Wei, Xin Yao, Yi Feher, Miklos Ban, Fuqiang Kiarash, Reza Green, Erin Mak, Tak W.Pan, Guohua Pauls, Henry W.	2013
	The discovery of polo-like kinase 4 inhibitors: Design and optimization of spiro[cyclopropane-1,3′[3H]indol]-2′(1′H).ones as orally bioavailable antitumor agents Journal:Journal of Medicinal Chemistry	Sampson, Peter B.Liu, Yong Patel, Narendra Kumar Feher, Miklos Forrest, Bryan Li, Sze Wan Edwards, Louise Laufer, Radoslaw Lang, Yunhui Ban, Fuqiang Awrey, Donald E.Mao, Guodong Plotnikova, Olga Leung, Genie Hodgson, Richard Mason, Jacqueline Wei, Xin Kiarash, Reza Green, Erin Qiu, Wei Chirgadze, Nickolay Y.Mak, Tak W.Pan, Guohua Pauls, Henry W.	2015	8
	The discovery of polo-like kinase 4 inhibitors: Identification of (1 R,2 S)-2-(3-((E)-4-(((cis)-2,6-Dimethylmorpholino)methyl)styryl)-1 H -indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a potent, orally active antitumor agent Journal:Journal of Medicinal Chemistry	Sampson, Peter B.Liu, Yong Forrest, Bryan Cumming, Graham Li, Sze Wan Patel, Narendra Kumar Edwards, Louise Laufer, Radoslaw Feher, Miklos Ban, Fuqiang Awrey, Donald E.Mao, Guodong Plotnikova, Olga Hodgson, Richard Beletskaya, Irina Mason, Jacqueline M.Luo, Xunyi Nadeem, Vincent Wei, Xin Kiarash, Reza Madeira, Brian Huang, Ping Mak, Tak W.Pan, Guohua Pauls, Henry W.	2015	7

Showing results 1 to 6 of 6