Browsing by Author Patel, Narendra Kumar

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Showing results 1 to 5 of 5
TitleAuthor(s)Issue Date
 
Design and optimization of (3-aryl-1H-indazol-6-yl)spiro[cyclopropane-1,3′-indolin]-2′-ones as potent PLK4 inhibitors with oral antitumor efficacy
Journal:Bioorganic and Medicinal Chemistry Letters
Li, Sze WanLiu, YongSampson, Peter B.Patel, Narendra KumarForrest, Bryan T.Edwards, LouiseLaufer, RadoslawFeher, MiklosBan, FuqiangAwrey, Donald E.Hodgson, RichardBeletskaya, IrinaMao, GuodongMason, Jacqueline M.Wei, XinLuo, XunyiKiarash, RezaGreen, ErinMak, Tak W.Pan, GuohuaPauls, Henry W.
2016
 
Discovery of Pyrazolo[1,5-a]pyrimidine TTK Inhibitors: CFI-402257 is a Potent, Selective, Bioavailable Anticancer Agent
Journal:ACS Medicinal Chemistry Letters
Liu, YongLaufer, RadoslawPatel, Narendra KumarNg, GraceSampson, Peter B.Li, Sze WanLang, YunhuiFeher, MiklosBrokx, RichardBeletskaya, IrinaHodgson, RichardPlotnikova, OlgaAwrey, Donald E.Qiu, WeiChirgadze, Nickolay Y.Mason, Jacqueline M.Wei, XinLin, Dan Chi ChiaChe, YiKiarash, RezaFletcher, Graham C.Mak, Tak W.Bray, Mark R.Pauls, Henry W.
2016
 
The discovery of orally bioavailable tyrosine threonine kinase (TTK) inhibitors: 3-(4-(heterocyclyl)phenyl)-1H-indazole-5-carboxamides as anticancer agents
Journal:Journal of Medicinal Chemistry
Liu, YongLang, YunhuiPatel, Narendra KumarNg, GraceLaufer, RadoslawLi, Sze WanEdwards, LouiseForrest, BryanSampson, Peter B.Feher, MiklosBan, FuqiangAwrey, Donald E.Beletskaya, IrinaMao, GuodongHodgson, RichardPlotnikova, OlgaQiu, WeiChirgadze, Nickolay Y.Mason, Jacqueline M.Wei, XinLin, Dan Chi ChiaChe, YiKiarash, RezaMadeira, BrianFletcher, Graham C.Mak, Tak W.Bray, Mark R.Pauls, Henry W.
2015
 
The discovery of polo-like kinase 4 inhibitors: Design and optimization of spiro[cyclopropane-1,3′[3H]indol]-2′(1′H).ones as orally bioavailable antitumor agents
Journal:Journal of Medicinal Chemistry
Sampson, Peter B.Liu, YongPatel, Narendra KumarFeher, MiklosForrest, BryanLi, Sze WanEdwards, LouiseLaufer, RadoslawLang, YunhuiBan, FuqiangAwrey, Donald E.Mao, GuodongPlotnikova, OlgaLeung, GenieHodgson, RichardMason, JacquelineWei, XinKiarash, RezaGreen, ErinQiu, WeiChirgadze, Nickolay Y.Mak, Tak W.Pan, GuohuaPauls, Henry W.
2015
 
The discovery of polo-like kinase 4 inhibitors: Identification of (1 R,2 S)-2-(3-((E)-4-(((cis)-2,6-Dimethylmorpholino)methyl)styryl)-1 H -indazol-6-yl)-5′-methoxyspiro[cyclopropane-1,3′-indolin]-2′-one (CFI-400945) as a potent, orally active antitumor agent
Journal:Journal of Medicinal Chemistry
Sampson, Peter B.Liu, YongForrest, BryanCumming, GrahamLi, Sze WanPatel, Narendra KumarEdwards, LouiseLaufer, RadoslawFeher, MiklosBan, FuqiangAwrey, Donald E.Mao, GuodongPlotnikova, OlgaHodgson, RichardBeletskaya, IrinaMason, Jacqueline M.Luo, XunyiNadeem, VincentWei, XinKiarash, RezaMadeira, BrianHuang, PingMak, Tak W.Pan, GuohuaPauls, Henry W.
2015
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