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Title	Author(s)	Issue Date	Views
7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease Journal:Neuropsychopharmacology	Zhang, Zhentao Liu, Xia Schroeder, Jason P.Chan, Chi Bun Song, Mingke Yu, Shan Ping Weinshenker, David Ye, Keqiang	2014	49
A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect Journal:Journal of Medicinal Chemistry	Liu, Xia Chan, Chi Bun Jang, Sung Wuk Pradoldej, Sompol Huang, Junjian He, Kunyan Phun, Lien H.France, Stefan Xiao, Ge Jia, Yonghui Luo, Hongbo R.Ye, Keqiang	2010	60
Acridine yellow G blocks glioblastoma growth via dual inhibition of epidermal growth factor receptor and protein kinase C kinases Journal:Journal of Biological Chemistry	Qi, Qi He, Kunyan Yoo, Min Heui Chan, Chi Bun Liu, Xia Zhang, Zhaobin Olson, Jeffrey J.Xiao, Ge Wang, Liya Mao, Hui Fu, Haian Tao, Hui Ramalingam, Suresh S.Sun, Shi Yong Mischel, Paul S.Ye, Keqiang	2012	44
Amitriptyline is a TrkA and TrkB Receptor Agonist that Promotes TrkA/TrkB Heterodimerization and Has Potent Neurotrophic Activity Journal:Chemistry and Biology	Jang, Sung Wuk Liu, Xia Chan, Chi Bun Weinshenker, David Hall, Randy A.Xiao, Ge Ye, Keqiang	2009	47
Biochemical and biophysical investigation of the brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone in the binding and activation of the trkb receptor Journal:Journal of Biological Chemistry	Liu, Xia Obiany, Obiamaka Chan, Chi Bun Huang, Junjian Xue, Shenghui Yang, Jenny J.Zeng, Fanxing Goodman, Mark Ye, Keqiang	2014	46
Blockade of glioma proliferation through allosteric inhibition of JAK2 Journal:Science Signaling	He, Kunyan Qi, Qi Chan, Chi Bun Xiao, Ge Liu, Xia Tucker-Burden, Carol Wang, Liya Mao, Hui Lu, Xiang McDonald, Frank E.Luo, Hongbo Fan, Qi Wen Weiss, William A.Sun, Shi Yong Brat, Daniel J.Ye, Keqiang	2013	44
Deficiency of phosphoinositide 3-kinase enhancer protects mice from diet-induced obesity and insulin resistance Journal:Diabetes	Chan, Chi Bun Liu, Xia Jung, Dae Young Jun, John Y.Luo, Hongbo R.Kim, Jason K.Ye, Keqiang	2010	43
Deoxygedunin, a natural product with potent neurotrophic activity in mice Journal:PLoS ONE	Jang, Sung Wuk Liu, Xia Chan, Chi Bun France, Stefan A.Sayeed, Iqbal Tang, Wenxue Lin, Xi Xiao, Ge Andero, Raul Chang, Qiang Ressler, Kerry J.Ye, Keqiang	2010	42
Essential role of PIKE GTPases in neuronal protection against excitotoxic insults Journal:Advances in Biological Regulation	Chan, Chi Bun Chen, Yongjun Liu, Xia Papale, Ligia Escayg, Andrew Mei, Lin Ye, Keqiang	2012	35
Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome Journal:Journal of Neuroscience	Gross, Christina Nakamoto, Mika Yao, Xiaodi Chan, Chi Bun Yim, So Y.Ye, Keqiang Warren, Stephen T.Bassell, Gary J.	2010	40
Fyn regulates adipogenesis by promoting PIKE-A/STAT5a interaction Journal:Molecular and Cellular Biology	Tse, Margaret Chui Ling Liu, Xia Yang, Seran Ye, Keqiang Chan, Chi Bun	2013	52
Identification of a molecular activator for insulin receptor with potent anti-diabetic effects Journal:Journal of Biological Chemistry	He, Kunyan Chan, Chi Bun Liu, Xia Jia, Yonghui Luo, Hongbo R.France, Stefan A.Liu, Yang Wilson, W. David Ye, Keqiang	2011	34
Identification of a molecular activator for insulin receptor with potent anti-diabetic effects (Journal of Biological Chemistry (2011) 286, (37379-37388)) Journal:Journal of Biological Chemistry	He, Kunyan Chan, Chi Bun Liu, Xia Jia, Yonghui Luo, Hongbo R.France, Stefan A.Liu, Yang Wilson, W. David Ye, Keqiang	2012	30
Identification of a small molecular insulin receptor agonist with potent antidiabetes activity Journal:Diabetes	Qiang, Guifen Xue, Shenghui Yang, Jenny J.Du, Guanhua Pang, Xiaobin Li, Xiaoting Goswami, Devrishi Griffin, Patrick R.Ortlund, Eric A.Chan, Chi Bun Ye, Keqiang	2014	46
Increased Expression of the PI3K Enhancer PIKE Mediates Deficits in Synaptic Plasticity and Behavior in Fragile X Syndrome Journal:Cell Reports	Gross, Christina Chang, Chia Wei Kelly, Seth M.Bhattacharya, Aditi McBride, Sean M J Danielson, Scott W.Jiang, Michael Q.Chan, Chi Bun Ye, Keqiang Gibson, Jay R.Klann, Eric Jongens, Thomas A.Moberg, Kenneth H.Huber, Kimberly M.Bassell, Gary J.	2015	37
Inhibition of mammalian target of rapamycin induces phosphatidylinositol 3-kinase-dependent and Mnk-mediated eukaryotic translation initiation factor 4E phosphorylation Journal:Molecular and Cellular Biology	Wang, Xuerong Yue, Ping Chan, Chi Bun Ye, Keqiang Ueda, Takeshi Watanabe-Fukunaga, Rie Fukunaga, Rikiro Fu, Haian Khuri, Fadlo R.Sun, Shi Yong	2007	33
Mice lacking asparaginyl endopeptidase develop disorders resembling hemophagocytic syndrome Journal:Proceedings of the National Academy of Sciences of the United States of America	Chan, Chi Bun Abe, Michiyo Hashimoto, Noriyoshi Hao, Chunhai Williams, Ifor R.Liu, Xia Nakao, Shinji Yamamoto, Akitsugu Li, Shi Yong Hara-Nishimura, Ikuko Asano, Masahide Ye, Keqiang	2009	39
Multiple functions of Phosphoinositide-3 Kinase Enhancer (PIKE) Journal:TheScientificWorldJournal	Chan, Chi Bun Ye, Keqiang	2010	40
Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B Journal:Nature Cell Biology	Tang, Xiaoling Jang, Sung Wuk Okada, Masashi Chan, Chi Bun Feng, Yue Liu, Yu Luo, Shi Wen Hong, Yan Rama, Nicolas Xiong, Wen Cheng Mehlen, Patrick Ye, Keqiang	2008	40
Optimization of a small tropomyosin-related kinase B (TrkB) agonist 7,8-dihydroxyflavone active in mouse models of depression Journal:Journal of Medicinal Chemistry	Liu, Xia Chan, Chi Bun Qi, Qi Xiao, Ge Luo, Hongbo R.He, Xiaolin Ye, Keqiang	2012	44

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