Myometrial cells modulate the activities of endometrial mesenchymal-like stem cells
Grant Data
Project Title
Myometrial cells modulate the activities of endometrial mesenchymal-like stem cells
Principal Investigator
Professor Ng, Ernest Hung Yu
(Principal Investigator (PI))
Co-Investigator(s)
Professor Yeung William Shu Biu
(Co-Investigator)
Dr Lee Calvin Kai Fai
(Co-Investigator)
Dr Chan Rachel Wah Shan
(Co-Investigator)
Duration
42
Start Date
2016-01-01
Amount
889107
Conference Title
Myometrial cells modulate the activities of endometrial mesenchymal-like stem cells
Presentation Title
Keywords
endometrial stem cells, matrix metalloproteinase 3, myometrial cells, Wnt signaling
Discipline
Reproduction
Panel
Biology and Medicine (M)
HKU Project Code
17125815
Grant Type
General Research Fund (GRF)
Funding Year
2015
Status
Completed
Objectives
1 To determine the role of myometrial cells on the clonogenicity and proliferation of endometrial mesenchymal-like stem cells. 2 To determine the role of Wnt signalling in the myometrial cells-induced increase in clonogenicity and proliferation of endometrial mesenchymal-like stem cells. 3 To study the actions of myometrial cell-derived matrix metalloproteinase-3 on clonogenicity and proliferation of the endometrial mesenchymal-like stem cells.