Regulation of non-canonical Wnt/PCP signaling by Vangl2 phosphorylation
Grant Data
Project Title
Regulation of non-canonical Wnt/PCP signaling by Vangl2 phosphorylation
Principal Investigator
Dr Gao, Bo
(Principal Investigator (PI))
Duration
36
Start Date
2017-07-01
Amount
1313444
Conference Title
Regulation of non-canonical Wnt/PCP signaling by Vangl2 phosphorylation
Presentation Title
Keywords
casein kinase 1 (CK1), non-canonical Wnt signaling, planar cell polarity (PCP), Vangl2, Wnt signaling
Discipline
Signal Transduction,Cell Biology
Panel
Biology and Medicine (M)
HKU Project Code
27115317
Grant Type
Early Career Scheme (ECS)
Funding Year
2017
Status
Completed
Objectives
1 Examining the dose-dependent effect of Vangl2 phosphorylation in mouse models 2 Defining the role of casein kinase-1 in the phosphorylation of Vangl2 3 Delineating the mechanism of Vangl2 phosphorylation in regulating Wnt/PCP
All Publications
| Title | Author(s) | Issue Date | |
|---|---|---|---|
| 2017 | |||
| 2021 | |||
Coordinated directional outgrowth and pattern formation by integration of Wnt5a and Fgf signaling in planar cell polarity Journal:Development (Cambridge) | 2018 |