Development of Small-Molecule Modulators of the Secretin Receptor as Novel Anti-Hypertensive Agents

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Grant Data
Project Title
Development of Small-Molecule Modulators of the Secretin Receptor as Novel Anti-Hypertensive Agents
Principal Investigator
Professor Chow, Billy Kwok Chong   (Principal Investigator (PI))
Duration
12
Start Date
2022-10-06
Amount
389000
Conference Title
Development of Small-Molecule Modulators of the Secretin Receptor as Novel Anti-Hypertensive Agents
Keywords
Positive Allosteric Modulators (PAM), Resistant hypertension, Drug Discovery, Secretin receptor, Pre-clinical studies
Discipline
Drug Discovery and DeliveryDrug Pharmacokinetics and Pharmacodynamics
HKU Project Code
HLCA/M-703/22
Grant Type
Healthy Longevity Catalyst Awards (Hong Kong) 2022
Funding Year
2022
Status
On-going
Objectives
Our major goal in the development of this drug is to finish the preclinical studies for KSD179019 and analogues. Afterwards we will seek aid from big-pharma companies for clinical trials and commercialization.