HKU Scholars Hub: Project

Developmental genomics and skeletal research

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Grant Data

Project Title

Developmental genomics and skeletal research

Principal Investigator

Professor Cheah, Kathryn Song Eng (Principal Investigator (PI))

Co-Investigator(s)

Professor Sham Pak Chung (Co-principal investigator)

Professor Shum Daisy Kwok Yan (Co-principal investigator)

Professor Chan Danny (Co-principal investigator)

Professor Huang Jiandong (Co-principal investigator)

Dr Song You-qiang (Co-principal investigator)

Dr Smith David Keith (Co-principal investigator)

Professor Sham Mai Har (Co-principal investigator)

Professor Cheung Kenneth Man Chee (Co-principal investigator)

Professor Jin Dong-Yan (Co-principal investigator)

Emeritus Professor Luk Keith Dip Kei (Co-principal investigator)

Duration

120

Start Date

2004-04-01

Amount

80974000

Conference Title

Developmental genomics and skeletal research

Presentation Title

Keywords

genomics and skeletal research

Discipline

Others - Medicine, Dentistry and Health

HKU Project Code

AoE/M-04/04

Grant Type

Areas of Excellence Scheme

Funding Year

2003

Status

Completed

All Publications

Title	Author(s)	Issue Date
The use of a modified fulcrum for fulcrum bending radiographs: a technical note Journal:Journal of Orthopaedic Surgery	Cheung, KMC Lam, JWN Samartzis, D Lu, WW Luk, KDK	2014
A splice-site mutation leads to haploinsufficiency of EXT2 mRNA for a dominant trait in a large family with multiple osteochondromas. Journal:Journal of orthopaedic research : official publication of the Orthopaedic Research Society	Yang, L Hui, WS Chan, WC Ng, VC Yam, TH Leung, HC Huang, JD Shum, DK Jie, Q Cheung, KM Cheah, KS Luo, Z Chan, D	2010
SOX9 induces and maintains neural stem cells Journal:Nature Neuroscience	Scott, CE Wynn, SL Sesay, A Cruz, C Cheung, M Gaviro, MVG Booth, S Gao, B Cheah, KSE LovellBadge, R Briscoe, J	2010
SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression Journal:PLoS Genetics	Leung, VYL Gao, B Leung, KKH Melhado, IG Wynn, SL Au, TYK Dung, NWF Lau, JYB Mak, ACY Chan, D Cheah, KSE	2011
SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation Journal:Cancer Research	Thomsen, MK Ambroisine, L Wynn, S Cheah, KSE Foster, CS Fisher, G Berney, DM Møller, H Reuter, VE Scardino, P Cuzick, J Ragavan, N Singh, PB Martin, FL Butler, CM Cooper, CS Swain, A Transatlantic Prostate Group	2010
SNP rs11190870 near LBX1 is associated with adolescent idiopathic scoliosis in southern Chinese Journal:Journal of Human Genetics	Fan, YH Song, YQ Chan, D Takahashi, Y Ikegawa, S Matsumoto, M Kou, I Cheah, KSE Sham, P Cheung, KMC Luk, KDK	2012
Reducing radiation exposure in early-onset scoliosis surgery patients: novel use of ultrasonography to measure lengthening in magnetically-controlled growing rods Journal:The Spine journal	Stokes, OM O'Donovan, E Samartzis, D Bow, HYC Luk, KDK Cheung, KMC	2014
Prevalence, determinants, and association of schmorl nodes of the lumbar spine with disc degeneration: a population-based study of 2449 individuals Proceeding/Conference:Spine	Mok, FPS Samartzis, D Karppinen, J Luk, KDK Fong, DYT Cheung, KMC	2010
Predicting the spatiotemporal dynamics of hair follicle patterns in the developing mouse Journal:Proceedings of the National Academy of Sciences	Cheng, CCW Niu, B Warren, M Pevny, LH Lovell-Badge, RH Hwa, TT Cheah, KSE	2014
Phosphorylation of Sox9 is required for neural crest delamination and is regulated downstream of BMP and canonical Wnt signaling Journal:Proceedings of the National Academy of Sciences	Liu, AJ Wu, MH Yan, HC Chau, KHB So, H Ng, A Chan, A Cheah, KSE Briscoe, J Cheung, MCH	2013