The role of human decidualized endometrial stromal cells invasion induced by trophoblastic spheroids for predicting pregnancy outcomes of in vitro fertilization
Grant Data
Project Title
The role of human decidualized endometrial stromal cells invasion induced by trophoblastic spheroids for predicting pregnancy outcomes of in vitro fertilization
Principal Investigator
Dr Lee, Cherie Yin Lau
(Principal Investigator (PI))
Co-Investigator(s)
Dr Lam Ka Wai
(Co-Investigator)
Professor Li Raymond Hang Wun
(Co-principal investigator)
Professor Ng Ernest Hung Yu
(Co-principal investigator)
Professor Yeung William Shu Biu
(Co-principal investigator)
Dr Chen Chun Hang
(Co-principal investigator)
Duration
24
Start Date
2023-07-01
Amount
1109000
Conference Title
The role of human decidualized endometrial stromal cells invasion induced by trophoblastic spheroids for predicting pregnancy outcomes of in vitro fertilization
Keywords
repeated implantation failure, endometrial stromal cells, in vitro fertilization, trophoblastic spheriods, cell invasion
Discipline
Others - Medicine, Dentistry and Health
Panel
Biology and Medicine (M)
HKU Project Code
10212996
Grant Type
Health and Medical Research Fund 2021
Funding Year
2021
Status
On-going
Objectives
To delineate the molecular interaction between decidual human endometrial stromal cells (d-EnSC) and human embryonic stem cell derived trophoblastic spheroids (BAP-EB), and to evaluate the use of BAP-EB-induced d-EnSC invasion as a predictor for cumulative live birth rate in infertile women undergoing IVF