STING agonist as a novel immunotherapy for liver cancers
Grant Data
Project Title
STING agonist as a novel immunotherapy for liver cancers
Principal Investigator
Dr Chan, Yuen Ki
(Principal Investigator (PI))
Duration
36
Start Date
2023-06-01
Amount
13130
Conference Title
STING agonist as a novel immunotherapy for liver cancers
Keywords
STING, agonist, novel, immunotherapy, liver
Discipline
CancerGastroenterology/Hepatobiliary
Panel
Biology and Medicine (M)
HKU Project Code
PDFS2324-7S04
Grant Type
RGC Postdoctoral Fellowship Scheme 2023/24
Funding Year
2023
Status
On-going
Objectives
Objective 1: To investigate the clinical relevance of STING expression in immune cellsand liver cancersObjective 2: To test the treatment efficacy and toxicity of STING agonist in liver cancersusing preclinical mouse modelsObjective 3: To examine the treatment efficacy of STING agonist in anti-PD-1 resistantliver cancers using preclinical mouse models