Wearable closed-loop neural control ‘Remind-to-move’ treatment for hemiparetic upper extremity in people with hemiplegia after stroke

Professor Lou, Vivian Weiqun   (Co-Principal Investigator (Co-PI) (for projects led by other university))

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2021-05-01

280000

Wearable closed-loop neural control ‘Remind-to-move’ treatment for hemiparetic upper extremity in people with hemiplegia after stroke

stroke, upper extremity, remind-to-move, closed-loop, wearable device

Rehabilitative and Physical MedicinePsychosocial and Behavioural Research

R5028-20

Research Impact Fund (RIF) 2020/21

2020

On-going

(1) To develop a bilateral arm movement synchronized recording system to measure the bilateralmovements of both arms in everyday life for people with hemiplegia after stroke;(2) To examine the effects of closed-loop and open-loop ‘Remind-to-move’ (RTM) treatmentprotocols using sensory cueing wristwatch devices to promote upper extremity recovery in terms ofa proof-of-concept pilot randomized controlled trial;(3) To develop a novel closed-loop sensorimotor RTM protocol that reinforces neuromuscularelectrical stimulation (NMES) for wrist extension based on an individual movement pattern inducedby the actual non-use of the affected upper extremity after stroke;(4) To compare, using a randomized clinical trial, the effects that an open-loop RTM treatment and ahybrid closed-loop RTM treatment augmented with functional electrical stimulation (FES) in taskspecific training have on the recovery of a hemiparetic upper extremity after stroke; and(5) To examine the longitudinal relationship between event-related desynchronization (ERD) byscalp electroencephalography (EEG) in core and adjacent movement-related regions in the primarymotor cortex (M1) when used as a neurophysiological biomarker for the trajectory of patients’ motorrecovery of their upper extremity, at various time points after stroke.