Transmission of antimicrobial resistance from hotspot sources to occupational populations and urban communities
Grant Data
Project Title
Transmission of antimicrobial resistance from hotspot sources to occupational populations and urban communities
Principal Investigator
Professor Cowling, Benjamin John
(Co-Principal Investigator (Co-PI) (for projects led by other university))
Co-Investigator(s)
Professor Li Xiangdong
(Principal investigator)
Duration
36
Start Date
2023-06-30
Amount
878768
Conference Title
Transmission of antimicrobial resistance from hotspot sources to occupational populations and urban communities
Keywords
Antimicrobial resistance, urban communities, occupational populations, hotspot sources, transmission
Discipline
Microbiology
HKU Project Code
C5063-22G
Grant Type
Collaborative Research Fund (CRF) - Group Research Project 2022/2023
Funding Year
2022
Status
On-going
Objectives
We will compare the prevalence and profiles of AMR between employees working in wastewater treatment plants and public hospitals in Hong Kong and non-working personnel (e.g., connected household members and urban residents) to examine the importance of different transmission routes leading to occupational acquisition of AMR, and probe the environmental remodeling mechanisms by which exogenous AMR colonize the occupational groups. We will then develop and evaluate a number of innovative and effective technologies ranging from spray control to antimicrobial surface coatings at the critical transmission step(s). The effectiveness of potential interventions in reducing occupational exposure and secondary transmission will be assessed within a dynamic model of AMR transmission pathways.