A multicenter, open-label study to evaluate simvastatin 20, 40 and 80mg in patients with coronary heart disease


Grant Data
Project Title
A multicenter, open-label study to evaluate simvastatin 20, 40 and 80mg in patients with coronary heart disease
Principal Investigator
Dr Lee, Kathy Lai Fun   (Principal Investigator (PI))
Co-Investigator(s)
Professor Lau Chu Pak   (Co-Investigator)
Dr Lee   (Co-Investigator)
Duration
8
Start Date
1999-07-29
Amount
0
Conference Title
A multicenter, open-label study to evaluate simvastatin 20, 40 and 80mg in patients with coronary heart disease
Presentation Title
Keywords
null
Discipline
N/A
HKU Project Code
N/A
Grant Type
Other Funding Scheme
Funding Year
1999
Status
Completed
Objectives
Using a titrate-to-goal with simvastatin doses of 20, 40, and 80mg/day, to determine (a) the percent of patients attaining a LDL goal of <= 100mg/dl; (b) the percentchange from baseline for lipid parameters, achieved by this regime; to evaluate the tolerability of simvastatin 20, 40, 80mg in patients with coronary heart disease; to evaluate patient discontinuation rates and patient compliance to different doses.