Sonodynamic-mediated microneedle array engineered with modified zinc-based metal-organic framework (MOF) antibacterial nano-particles enabling subcutaneous administration for wound infectio

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Grant Data
Project Title
Sonodynamic-mediated microneedle array engineered with modified zinc-based metal-organic framework (MOF) antibacterial nano-particles enabling subcutaneous administration for wound infectio
Principal Investigator
Professor Yeung, Kelvin Wai Kwok   (Principal Investigator (PI))
Co-Investigator(s)
Mr Mao Congyang   (Co-Investigator)
Mr. XIANG Yiming   (Co-Investigator)
Professor Kao Richard Yi Tsun   (Co-Investigator)
Duration
36
Start Date
2024-10-01
Amount
1365600
Conference Title
Sonodynamic-mediated microneedle array engineered with modified zinc-based metal-organic framework (MOF) antibacterial nano-particles enabling subcutaneous administration for wound infectio
Keywords
Wound infection, Antibacterial, Sonodynamic control, Ultra-responsive nano-, Reactive oxygen
Discipline
Orthopaedics/Traumatology
HKU Project Code
23220952
Grant Type
Health and Medical Research Fund 2022
Funding Year
2022
Status
On-going
Objectives
To investigate the ZnO-based (ZnTCPP@ZnO) antibacterial nanostructures of an embedded hydrogel, which can modulate ROS release through sonodynamic control.