Essential role of SMAD3 in cardiac repair and fibrosis

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Grant Data
Project Title
Essential role of SMAD3 in cardiac repair and fibrosis
Principal Investigator
Professor Lan, Hui Yao   (Principal Investigator (PI))
Duration
36
Start Date
2006-08-16
Completion Date
2009-08-31
Amount
342616
Conference Title
Essential role of SMAD3 in cardiac repair and fibrosis
Keywords
Cardiac fibrosis, hypertension, Smad3, TGF-beta
Discipline
Cardiovascular Research
HKU Project Code
N/A
Grant Type
Sun Chieh Yeh Heart Foundation - General Award
Funding Year
2006
Status
Completed
Objectives
To investigate the signaling mechansims of TGF-beta/Smad3 in cardiac fibrosis induced in Smad3 knockout mice by angiotensin II infusion or by cardiac ischemic injury.