The effect of melatonin in the treatment of thrombocytopenia

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Grant Data
Project Title
The effect of melatonin in the treatment of thrombocytopenia
Principal Investigator
Dr Yang, Mo   (Principal Investigator (PI))
Duration
12
Start Date
2008-01-01
Completion Date
2008-12-31
Amount
25000
Conference Title
The effect of melatonin in the treatment of thrombocytopenia
Keywords
haematopoietic stem cells, megakaryocytes, Melatonin, Thrombocytopenia, thrombopoiesis
Discipline
Blood/HematologyPaediatrics
HKU Project Code
N/A
Grant Type
Queen Mary Hospital Charitable Trust - Training and Research Assistance Scheme
Funding Year
2007
Status
Completed
Objectives
To investigate the mitogenic effect of MLT on in-vitro megakaryocytopoiesis and proplatelet formation; to analyze the effect of MLT on thrombopoiesis in a thrombocytopenic model; to analyze the role of G-protein receptors on megakaryocytopoiesis and proplatelet formation in a G i2-deficient mice.