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Conference Paper: Executive disorders in patients with schizophrenia and its correlates with neurological signs

TitleExecutive disorders in patients with schizophrenia and its correlates with neurological signs
Authors
Issue Date2002
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schres
Citation
The 11th Biennial Winter Workshop on Schizophrenia, Davos, Switzerland, 24 February-1 March 2002. In Schizophrenia Research, 2002, v. 53 n. 3, suppl. 1, p. 137, abstract A297 How to Cite?
AbstractBoth neuropsychological impairments and neurological signs are often demonstrated in schizophrenia. However, very few studies have been conducted to investigate relationship between executive functions and sub-groups of neurological signs. This study was designed to address such issue. A total of 51 patients with chronic schizophrenia were recruited. The Sustained Attention Response to Task ŽSART., Six Elements Test ŽSET., and Hayling Sentence Completion Test ŽHSC. were used to assess executive functions. The Cambridge Neurological Inventory was used to assess the neurological signs. Three factors were identified within the executive function tests: Ž1. Semantic inhibition factor comprised the items in HSC, Ž2. Action rattention inhibition factor comprised the SART commission error and SET rule-breaking score, and Ž3. Output generation factor comprised the SET raw score and SART correct response. Significant and modest relationships were found between these derived factors and clinical symptoms after partial ling out the confounding effect of age, education and illness duration. However, such relationships were not so clear-cut between the derived factors and neurological signs. In conclusion, the three tests of executive function were shown to have good construct validity among a group of chronic schizophrenic patients. The derived factors seem to share common neural substrates with the general symptomatology of schizophrenia. However, there is not a simple relationship between neuropsychological impairments and neurological signs. The basis of this relationship has yet to be elucidated in future study.
DescriptionThis journal suppl. entitled: XIth Biennial Winter Workshop on Schizophrenia
Persistent Identifierhttp://hdl.handle.net/10722/105466
ISSN
2023 Impact Factor: 3.6
2023 SCImago Journal Rankings: 1.374

 

DC FieldValueLanguage
dc.contributor.authorChan, RCKen_HK
dc.contributor.authorChen, EYHen_HK
dc.contributor.authorChen, RYLen_HK
dc.contributor.authorCheung, HKen_HK
dc.date.accessioned2010-09-25T22:35:18Z-
dc.date.available2010-09-25T22:35:18Z-
dc.date.issued2002en_HK
dc.identifier.citationThe 11th Biennial Winter Workshop on Schizophrenia, Davos, Switzerland, 24 February-1 March 2002. In Schizophrenia Research, 2002, v. 53 n. 3, suppl. 1, p. 137, abstract A297en_HK
dc.identifier.issn0920-9964en_HK
dc.identifier.urihttp://hdl.handle.net/10722/105466-
dc.descriptionThis journal suppl. entitled: XIth Biennial Winter Workshop on Schizophrenia-
dc.description.abstractBoth neuropsychological impairments and neurological signs are often demonstrated in schizophrenia. However, very few studies have been conducted to investigate relationship between executive functions and sub-groups of neurological signs. This study was designed to address such issue. A total of 51 patients with chronic schizophrenia were recruited. The Sustained Attention Response to Task ŽSART., Six Elements Test ŽSET., and Hayling Sentence Completion Test ŽHSC. were used to assess executive functions. The Cambridge Neurological Inventory was used to assess the neurological signs. Three factors were identified within the executive function tests: Ž1. Semantic inhibition factor comprised the items in HSC, Ž2. Action rattention inhibition factor comprised the SART commission error and SET rule-breaking score, and Ž3. Output generation factor comprised the SET raw score and SART correct response. Significant and modest relationships were found between these derived factors and clinical symptoms after partial ling out the confounding effect of age, education and illness duration. However, such relationships were not so clear-cut between the derived factors and neurological signs. In conclusion, the three tests of executive function were shown to have good construct validity among a group of chronic schizophrenic patients. The derived factors seem to share common neural substrates with the general symptomatology of schizophrenia. However, there is not a simple relationship between neuropsychological impairments and neurological signs. The basis of this relationship has yet to be elucidated in future study.-
dc.languageengen_HK
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/schresen_HK
dc.relation.ispartofSchizophrenia Researchen_HK
dc.rightsSchizophrenia Research. Copyright © Elsevier BV.en_HK
dc.titleExecutive disorders in patients with schizophrenia and its correlates with neurological signsen_HK
dc.typeConference_Paperen_HK
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=0920-9964&volume=53&issue=3&spage=137&epage=&date=2002&atitle=Executive+disorders+in+patients+with+schizophrenia+and+its+correlates+with+neurological+signsen_HK
dc.identifier.emailChan, RCK: ckrchan@graduate.hku.hken_HK
dc.identifier.emailChen, EYH: eyhchen@hku.hken_HK
dc.identifier.emailChen, RYL: rylchen@hkucc.hku.hken_HK
dc.identifier.emailCheung, HK: cheung_hk@yahoo.comen_HK
dc.identifier.doi10.1016/S0920-9964(01)00381-4-
dc.identifier.scopuseid_2-s2.0-0037082185-
dc.identifier.hkuros73338en_HK
dc.identifier.volume53en_HK
dc.identifier.issue3 suppl. 1en_HK
dc.identifier.spage137, abstract A297en_HK
dc.identifier.epage137, abstract A297-
dc.identifier.issnl0920-9964-

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