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Conference Paper: Human cytomegalovirus inhibited megakaryocytic differentiation, maturation and induced apoptosis in vitro
Title | Human cytomegalovirus inhibited megakaryocytic differentiation, maturation and induced apoptosis in vitro |
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Authors | |
Issue Date | 2009 |
Citation | The 51st ASH Annual Meeting And Exposition, New Orleans, LA., 5-8 December 2009. How to Cite? |
Abstract | Human cytomegalovirus (HCMV) can cause life-threatening infection in immunocomprimised individuals, such as patients undergoing intensive chemotherapy or bone marrow transplantation. Thrombocytopenia is one of the manifestations in active HCMV infection, which may be a consequence of viral suppression on megakaryopoiesis. The exact underline mechanisms remain uncertain. Our previous studies suggested that HCMV directly infects megakaryocytic progenitors and inhibits their proliferation. Colony-formation of HCMV-infected CFU-MK decreased in ... |
Description | Poster Session: Disorders of Platelet Number or Function Poster II: abstract no. 2413 |
Persistent Identifier | http://hdl.handle.net/10722/126853 |
DC Field | Value | Language |
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dc.contributor.author | Chen, JL | en_HK |
dc.contributor.author | Chan, GCF | en_HK |
dc.contributor.author | Ye, JY | en_HK |
dc.contributor.author | He, ZX | en_HK |
dc.contributor.author | Wang, QW | en_HK |
dc.contributor.author | Pan, SN | en_HK |
dc.contributor.author | Li, XF | en_HK |
dc.contributor.author | Deng, RX | en_HK |
dc.contributor.author | Yang, M | en_HK |
dc.date.accessioned | 2010-10-31T12:52:24Z | - |
dc.date.available | 2010-10-31T12:52:24Z | - |
dc.date.issued | 2009 | en_HK |
dc.identifier.citation | The 51st ASH Annual Meeting And Exposition, New Orleans, LA., 5-8 December 2009. | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/126853 | - |
dc.description | Poster Session: Disorders of Platelet Number or Function Poster II: abstract no. 2413 | - |
dc.description.abstract | Human cytomegalovirus (HCMV) can cause life-threatening infection in immunocomprimised individuals, such as patients undergoing intensive chemotherapy or bone marrow transplantation. Thrombocytopenia is one of the manifestations in active HCMV infection, which may be a consequence of viral suppression on megakaryopoiesis. The exact underline mechanisms remain uncertain. Our previous studies suggested that HCMV directly infects megakaryocytic progenitors and inhibits their proliferation. Colony-formation of HCMV-infected CFU-MK decreased in ... | - |
dc.language | eng | en_HK |
dc.relation.ispartof | ASH Annual Meeting And Exposition | - |
dc.title | Human cytomegalovirus inhibited megakaryocytic differentiation, maturation and induced apoptosis in vitro | en_HK |
dc.type | Conference_Paper | en_HK |
dc.identifier.email | Chen, JL: jnlncn2003@yahoo.com | en_HK |
dc.identifier.email | Chan, GCF: gcfchan@hkucc.hku.hk | en_HK |
dc.identifier.email | Ye, JY: jieyu.ye@gmail.com | en_HK |
dc.identifier.email | Yang, M: yangm1091@yahoo.com.hk | en_HK |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.hkuros | 170442 | en_HK |
dc.description.other | The 51st ASH Annual Meeting And Exposition, New Orleans, LA., 5-8 December 2009. | - |