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Article: The association of early infections and atopic dermatitis. A retrospective case-control study in Chinese children in primary care in Hong Kong

TitleThe association of early infections and atopic dermatitis. A retrospective case-control study in Chinese children in primary care in Hong Kong
Authors
KeywordsAtopic dermatitis
Early infections
Hygiene hypothesis
Issue Date2006
Citation
European Journal Of Pediatric Dermatology, 2006, v. 16 n. 2, p. 101-104 How to Cite?
AbstractThe increasing prevalence of atopic dermatitis (AD) in developed countries has been postulated to be related to better hygiene leading to lack of exposure of infants to infections. The objective of this study is to investigate the association of early infections with AD in Chinese children in Hong Kong. Our setting were two primary care surgeries run by a family physician with training and qualifications in pediatrics and in dermatology. Most children were under our continuous care since early infancy. We searched our database and retrieved 132 medical records of infants and children (below eight) with AD fulfilling the United Kingdom Working Party diagnostic criteria of AD seen by us in 12 months. Children with a label of AD but not fulfilling the diagnostic criteria were excluded. Children who were not continuously cared by us since they were born were also excluded. For each child with AD, we retrieved the medical record of the next age-and-sex pair-matched child who did not have skin problems as controls. The number of children with infection before the age of six months, the number of infections, the number of hospitalizations, and the number of children having prescribed antibiotics before six months were insignificantly different in the study and control subjects. We conclude that there is no significant association between early infections and the risk of AD for Chinese children in Hong Kong.
Persistent Identifierhttp://hdl.handle.net/10722/132437
ISSN
2023 SCImago Journal Rankings: 0.116
References

 

DC FieldValueLanguage
dc.contributor.authorLee, Aen_HK
dc.contributor.authorChuh, Aen_HK
dc.contributor.authorWong, Wen_HK
dc.date.accessioned2011-03-28T09:24:36Z-
dc.date.available2011-03-28T09:24:36Z-
dc.date.issued2006en_HK
dc.identifier.citationEuropean Journal Of Pediatric Dermatology, 2006, v. 16 n. 2, p. 101-104en_HK
dc.identifier.issn1122-7672en_HK
dc.identifier.urihttp://hdl.handle.net/10722/132437-
dc.description.abstractThe increasing prevalence of atopic dermatitis (AD) in developed countries has been postulated to be related to better hygiene leading to lack of exposure of infants to infections. The objective of this study is to investigate the association of early infections with AD in Chinese children in Hong Kong. Our setting were two primary care surgeries run by a family physician with training and qualifications in pediatrics and in dermatology. Most children were under our continuous care since early infancy. We searched our database and retrieved 132 medical records of infants and children (below eight) with AD fulfilling the United Kingdom Working Party diagnostic criteria of AD seen by us in 12 months. Children with a label of AD but not fulfilling the diagnostic criteria were excluded. Children who were not continuously cared by us since they were born were also excluded. For each child with AD, we retrieved the medical record of the next age-and-sex pair-matched child who did not have skin problems as controls. The number of children with infection before the age of six months, the number of infections, the number of hospitalizations, and the number of children having prescribed antibiotics before six months were insignificantly different in the study and control subjects. We conclude that there is no significant association between early infections and the risk of AD for Chinese children in Hong Kong.en_HK
dc.languageengen_US
dc.relation.ispartofEuropean Journal of Pediatric Dermatologyen_HK
dc.subjectAtopic dermatitisen_HK
dc.subjectEarly infectionsen_HK
dc.subjectHygiene hypothesisen_HK
dc.titleThe association of early infections and atopic dermatitis. A retrospective case-control study in Chinese children in primary care in Hong Kongen_HK
dc.typeArticleen_HK
dc.identifier.emailWong, W:wongwcw@hku.hken_HK
dc.identifier.authorityWong, W=rp01457en_HK
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.scopuseid_2-s2.0-33749494375en_HK
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-33749494375&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume16en_HK
dc.identifier.issue2en_HK
dc.identifier.spage101en_HK
dc.identifier.epage104en_HK
dc.identifier.scopusauthoridLee, A=8305464500en_HK
dc.identifier.scopusauthoridChuh, A=7004650631en_HK
dc.identifier.scopusauthoridWong, W=25230779000en_HK
dc.identifier.issnl1122-7672-

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