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Conference Paper: Patterns of viral shedding in pandemic and seasonal influenza virus infections in a community setting
Title | Patterns of viral shedding in pandemic and seasonal influenza virus infections in a community setting |
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Authors | |
Keywords | Influenza Pandemic A ⁄ H1N1 Viral shedding |
Issue Date | 2011 |
Publisher | Blackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/subs.asp?ref=1750-2640&site=1 |
Citation | The 7th International Conference on Options for the Control of Influenza (Options-7), Hong Kong SAR, China, 3-7 September 2010. In Influenza and Other Respiratory Viruses, 2011, v. 5, suppl. 1, p. 301-303 How to Cite? |
Abstract | INTRODUCTION: The dynamics of pandemic influenza A⁄H1N1 compared to seasonal strains of influenza is not clearly understood. It is important to understand the patterns of viral shedding and symptoms over time in community-based infections. MATERIALS AND METHODS: Household infections were followed-up in two large community-based studies. Patterns of viral shedding, symptoms and signs, and tympanic temperature were plotted over time and grouped according to strain for analysis. RESULTS: The patterns of viral shedding, symptoms and signs, and tympanic temperature in three influenza A strains (pandemic A⁄ H1N1, seasonal A⁄ H1N1, and seasonal A⁄ H3N2) were comparable. Peak viral shedding occurred close to the onset of symptoms and resolved after 6–7 days. Patterns of viral shedding in influenza B virus infections differed. DISCUSSION: The patterns of viral shedding and clinical course of pandemic influenza A⁄H1N1 infections were broadly similar to seasonal influenza A⁄H1N1 and A⁄ H3N2. Only the clinical course of seasonal influenza B infections was similar to pandemic influenza A⁄ H1N1. The dynamics of pandemic influenza A⁄H1N1 were observed to be largely alike to the dynamics of seasonal influenza A⁄H1N1 and A⁄ H3N2. |
Description | This journal issue is the Special Issue: Options for the Control of Influenza VII ... 2010 |
Persistent Identifier | http://hdl.handle.net/10722/135658 |
ISSN | 2023 Impact Factor: 4.3 2023 SCImago Journal Rankings: 1.485 |
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lau, LLH | en_US |
dc.contributor.author | Fang, J | en_US |
dc.contributor.author | Chan, KH | en_US |
dc.contributor.author | Cheng, CKY | en_US |
dc.contributor.author | Peiris, JSM | en_US |
dc.contributor.author | Leung, GM | en_US |
dc.contributor.author | Cowling, BJ | en_US |
dc.date.accessioned | 2011-07-27T01:38:54Z | - |
dc.date.available | 2011-07-27T01:38:54Z | - |
dc.date.issued | 2011 | en_US |
dc.identifier.citation | The 7th International Conference on Options for the Control of Influenza (Options-7), Hong Kong SAR, China, 3-7 September 2010. In Influenza and Other Respiratory Viruses, 2011, v. 5, suppl. 1, p. 301-303 | en_US |
dc.identifier.issn | 1750-2640 | - |
dc.identifier.uri | http://hdl.handle.net/10722/135658 | - |
dc.description | This journal issue is the Special Issue: Options for the Control of Influenza VII ... 2010 | - |
dc.description.abstract | INTRODUCTION: The dynamics of pandemic influenza A⁄H1N1 compared to seasonal strains of influenza is not clearly understood. It is important to understand the patterns of viral shedding and symptoms over time in community-based infections. MATERIALS AND METHODS: Household infections were followed-up in two large community-based studies. Patterns of viral shedding, symptoms and signs, and tympanic temperature were plotted over time and grouped according to strain for analysis. RESULTS: The patterns of viral shedding, symptoms and signs, and tympanic temperature in three influenza A strains (pandemic A⁄ H1N1, seasonal A⁄ H1N1, and seasonal A⁄ H3N2) were comparable. Peak viral shedding occurred close to the onset of symptoms and resolved after 6–7 days. Patterns of viral shedding in influenza B virus infections differed. DISCUSSION: The patterns of viral shedding and clinical course of pandemic influenza A⁄H1N1 infections were broadly similar to seasonal influenza A⁄H1N1 and A⁄ H3N2. Only the clinical course of seasonal influenza B infections was similar to pandemic influenza A⁄ H1N1. The dynamics of pandemic influenza A⁄H1N1 were observed to be largely alike to the dynamics of seasonal influenza A⁄H1N1 and A⁄ H3N2. | - |
dc.language | eng | en_US |
dc.publisher | Blackwell Publishing Ltd. The Journal's web site is located at http://www.blackwellpublishing.com/subs.asp?ref=1750-2640&site=1 | - |
dc.relation.ispartof | Influenza and Other Respiratory Viruses | en_US |
dc.rights | The definitive version is available at www.blackwell-synergy.com | - |
dc.subject | Influenza | - |
dc.subject | Pandemic A ⁄ H1N1 | - |
dc.subject | Viral shedding | - |
dc.title | Patterns of viral shedding in pandemic and seasonal influenza virus infections in a community setting | en_US |
dc.type | Conference_Paper | en_US |
dc.identifier.email | Lau, LLH: lllau@HKUSUA.hku.hk | en_US |
dc.identifier.email | Fang, J: vickyf@hku.hk | en_US |
dc.identifier.email | Chan, KH: chankh2@HKUCC.hku.hk | en_US |
dc.identifier.email | Cheng, CKY: chengkyc@hkucc.hku.hk | en_US |
dc.identifier.email | Peiris, JSM: malik@hkucc.hku.hk | en_US |
dc.identifier.email | Leung, GM: gmleung@hku.hk | en_US |
dc.identifier.email | Cowling, BJ: bcowling@hku.hk | - |
dc.identifier.authority | Peiris, JSM=rp00410 | en_US |
dc.identifier.authority | Leung, GM=rp00460 | en_US |
dc.identifier.authority | Cowling, BJ=rp01326 | en_US |
dc.description.nature | link_to_OA_fulltext | - |
dc.identifier.doi | 10.1111/j.1750-2659.2011.00209.x | - |
dc.identifier.hkuros | 186241 | en_US |
dc.identifier.hkuros | 184231 | - |
dc.identifier.volume | 5 | en_US |
dc.identifier.issue | suppl. 1 | en_US |
dc.identifier.spage | 301 | en_US |
dc.identifier.epage | 303 | en_US |
dc.description.other | Options for the Control of Influenza VII, Hong Kong SAR, China, 3-7 September 2010. In Influenza and Other Respiratory Viruses, 2011, v. 5, suppl. 1, p. 301-303 | - |
dc.identifier.issnl | 1750-2640 | - |