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- Publisher Website: 10.1021/ja108673h
- Scopus: eid_2-s2.0-79953062762
- PMID: 21381735
- WOS: WOS:000291715300048
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Article: Dewetting-induced membrane formation by adhesion of amphiphile-laden interfaces
Title | Dewetting-induced membrane formation by adhesion of amphiphile-laden interfaces | ||||||||||
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Authors | |||||||||||
Issue Date | 2011 | ||||||||||
Publisher | American Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/jacsat/index.html | ||||||||||
Citation | Journal Of The American Chemical Society, 2011, v. 133 n. 12, p. 4420-4426 How to Cite? | ||||||||||
Abstract | We introduce an approach for forming bilayer polymer membranes by adhesion of amphiphile-laden interfaces. This adhesion is induced by a reduction of solvent quality for the amphiphilic diblock copolymers through selective evaporation of good solvent in the solvent mixture. By combining this membrane formation mechanism with a double-emulsion-templated approach for vesicle formation, we fabricate monodisperse polymersomes that exhibit excellent membrane uniformity, and structural stability, using a method that has high encapsulation efficiency. Moreover, we also show that the technique is versatile and can be applied to different block copolymers. The ability to direct the assembly of amphiphiles into a membrane creates new opportunities to engineer the structures of vesicles on the level of the individual bilayer leaflets. © 2011 American Chemical Society. | ||||||||||
Persistent Identifier | http://hdl.handle.net/10722/139371 | ||||||||||
ISSN | 2023 Impact Factor: 14.4 2023 SCImago Journal Rankings: 5.489 | ||||||||||
ISI Accession Number ID |
Funding Information: This work was supported by the NSF (No. DMR-10006546) and the Harvard MRSEC (No. DMR-0820484). H.C.S. and D.A.W. were supported in part by BASF Ludwigshafen in Germany. A.E. was supported by a National Institutes of Health Grant (No. HL007680). We thank Tom Kodger for help with DLS measurements, Debra Auguste for use of the freeze-dryer, as well as David Lange (Harvard CNS), Woods Hole Marine Biological Laboratory and Leica Microsystems, Inc. for the use and help with the cryo-SEM imaging. | ||||||||||
References |
DC Field | Value | Language |
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dc.contributor.author | Shum, HC | en_HK |
dc.contributor.author | SantanachCarreras, E | en_HK |
dc.contributor.author | Kim, JW | en_HK |
dc.contributor.author | Ehrlicher, A | en_HK |
dc.contributor.author | Bibette, J | en_HK |
dc.contributor.author | Weitz, DA | en_HK |
dc.date.accessioned | 2011-09-23T05:48:56Z | - |
dc.date.available | 2011-09-23T05:48:56Z | - |
dc.date.issued | 2011 | en_HK |
dc.identifier.citation | Journal Of The American Chemical Society, 2011, v. 133 n. 12, p. 4420-4426 | en_HK |
dc.identifier.issn | 0002-7863 | en_HK |
dc.identifier.uri | http://hdl.handle.net/10722/139371 | - |
dc.description.abstract | We introduce an approach for forming bilayer polymer membranes by adhesion of amphiphile-laden interfaces. This adhesion is induced by a reduction of solvent quality for the amphiphilic diblock copolymers through selective evaporation of good solvent in the solvent mixture. By combining this membrane formation mechanism with a double-emulsion-templated approach for vesicle formation, we fabricate monodisperse polymersomes that exhibit excellent membrane uniformity, and structural stability, using a method that has high encapsulation efficiency. Moreover, we also show that the technique is versatile and can be applied to different block copolymers. The ability to direct the assembly of amphiphiles into a membrane creates new opportunities to engineer the structures of vesicles on the level of the individual bilayer leaflets. © 2011 American Chemical Society. | en_HK |
dc.language | eng | en_US |
dc.publisher | American Chemical Society. The Journal's web site is located at http://pubs.acs.org/journals/jacsat/index.html | en_HK |
dc.relation.ispartof | Journal of the American Chemical Society | en_HK |
dc.subject.mesh | Membranes, Artificial | - |
dc.subject.mesh | Particle Size | - |
dc.subject.mesh | Polymers - chemistry | - |
dc.subject.mesh | Surface Properties | - |
dc.title | Dewetting-induced membrane formation by adhesion of amphiphile-laden interfaces | en_HK |
dc.type | Article | en_HK |
dc.identifier.email | Shum, HC:ashum@hku.hk | en_HK |
dc.identifier.authority | Shum, HC=rp01439 | en_HK |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1021/ja108673h | en_HK |
dc.identifier.pmid | 21381735 | - |
dc.identifier.scopus | eid_2-s2.0-79953062762 | en_HK |
dc.identifier.hkuros | 193598 | en_US |
dc.relation.references | http://www.scopus.com/mlt/select.url?eid=2-s2.0-79953062762&selection=ref&src=s&origin=recordpage | en_HK |
dc.identifier.volume | 133 | en_HK |
dc.identifier.issue | 12 | en_HK |
dc.identifier.spage | 4420 | en_HK |
dc.identifier.epage | 4426 | en_HK |
dc.identifier.eissn | 1520-5126 | - |
dc.identifier.isi | WOS:000291715300048 | - |
dc.publisher.place | United States | en_HK |
dc.identifier.scopusauthorid | Shum, HC=23976513800 | en_HK |
dc.identifier.scopusauthorid | SantanachCarreras, E=36654578200 | en_HK |
dc.identifier.scopusauthorid | Kim, JW=36012700600 | en_HK |
dc.identifier.scopusauthorid | Ehrlicher, A=36437057300 | en_HK |
dc.identifier.scopusauthorid | Bibette, J=7003384516 | en_HK |
dc.identifier.scopusauthorid | Weitz, DA=7006798731 | en_HK |
dc.identifier.issnl | 0002-7863 | - |