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- Publisher Website: 10.1586/eri.11.25
- Scopus: eid_2-s2.0-79955085527
- PMID: 21504401
- WOS: WOS:000290839700015
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Article: Production of influenza pseudotyped lentiviral particles and their use influenza research and diagnosis: an update
Title | Production of influenza pseudotyped lentiviral particles and their use influenza research and diagnosis: an update | ||||||||||
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Authors | |||||||||||
Keywords | characterization diagnostics influenza neutralization assay production pseudoparticles pseudotyped lentiviral particle | ||||||||||
Issue Date | 2011 | ||||||||||
Publisher | Expert Reviews Ltd. The Journal's web site is located at http://www.future-drugs.com/publication.asp?publicationid=7 | ||||||||||
Citation | Expert Review of Anti-Infective Therapy, 2011, v. 9 n. 4, p. 443-455 How to Cite? | ||||||||||
Abstract | Pseudotyped viral particles are being used as safe surrogates to mimic the structure and surface of many viruses, including highly pathogenic viruses such as avian influenza H5N1, to investigate biological functions mediated by the envelope proteins derived from these viruses. The first part of this article evaluates and discusses the differences in the production and characterization of influenza pseudoparticles. The second part focuses on the applications that such a flexible tool can provide in modern influenza research, in particular in the fields of drug discovery, molecular biology and diagnosis. | ||||||||||
Persistent Identifier | http://hdl.handle.net/10722/140759 | ||||||||||
ISSN | 2023 Impact Factor: 4.2 2023 SCImago Journal Rankings: 1.260 | ||||||||||
ISI Accession Number ID |
Funding Information: This work was supported by the University Grants Committee of the Hong Kong Special Administrative Region, China (Project No: AoE/M-12/06), the Research Grants Council of Hong Kong (HKU774109M), the French Ministry of Health, RESPARI Pasteur Network and the Li Ka Shing Foundation. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed. | ||||||||||
Grants |
DC Field | Value | Language |
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dc.contributor.author | Garcia, J | en_US |
dc.contributor.author | Lai, JCC | en_US |
dc.date.accessioned | 2011-09-23T06:18:26Z | - |
dc.date.available | 2011-09-23T06:18:26Z | - |
dc.date.issued | 2011 | en_US |
dc.identifier.citation | Expert Review of Anti-Infective Therapy, 2011, v. 9 n. 4, p. 443-455 | en_US |
dc.identifier.issn | 1478-7210 | - |
dc.identifier.uri | http://hdl.handle.net/10722/140759 | - |
dc.description.abstract | Pseudotyped viral particles are being used as safe surrogates to mimic the structure and surface of many viruses, including highly pathogenic viruses such as avian influenza H5N1, to investigate biological functions mediated by the envelope proteins derived from these viruses. The first part of this article evaluates and discusses the differences in the production and characterization of influenza pseudoparticles. The second part focuses on the applications that such a flexible tool can provide in modern influenza research, in particular in the fields of drug discovery, molecular biology and diagnosis. | - |
dc.language | eng | en_US |
dc.publisher | Expert Reviews Ltd. The Journal's web site is located at http://www.future-drugs.com/publication.asp?publicationid=7 | - |
dc.relation.ispartof | Expert Review of Anti-Infective Therapy | en_US |
dc.subject | characterization | - |
dc.subject | diagnostics | - |
dc.subject | influenza | - |
dc.subject | neutralization assay | - |
dc.subject | production | - |
dc.subject | pseudoparticles | - |
dc.subject | pseudotyped lentiviral particle | - |
dc.subject.mesh | Influenzavirus A - physiology | - |
dc.subject.mesh | Lentivirus - genetics - metabolism | - |
dc.subject.mesh | Membrane Glycoproteins - genetics - metabolism | - |
dc.subject.mesh | Orthomyxoviridae Infections - diagnosis - virology | - |
dc.subject.mesh | Viral Proteins - metabolism | - |
dc.title | Production of influenza pseudotyped lentiviral particles and their use influenza research and diagnosis: an update | en_US |
dc.type | Article | en_US |
dc.identifier.email | Garcia, J: jmgarcia@hku.hk | en_US |
dc.identifier.email | Lai, JCC: jimmylai@hkucc.hku.hk | en_US |
dc.description.nature | link_to_subscribed_fulltext | - |
dc.identifier.doi | 10.1586/eri.11.25 | - |
dc.identifier.pmid | 21504401 | - |
dc.identifier.scopus | eid_2-s2.0-79955085527 | - |
dc.identifier.hkuros | 194077 | en_US |
dc.identifier.volume | 9 | en_US |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 443 | en_US |
dc.identifier.epage | 455 | en_US |
dc.identifier.isi | WOS:000290839700015 | - |
dc.publisher.place | United Kingdom | - |
dc.relation.project | Control of Pandemic and Inter-pandemic Influenza | - |
dc.identifier.citeulike | 9196789 | - |
dc.identifier.issnl | 1478-7210 | - |